Young-Onset Dementia Among Individuals With History of Preeclampsia

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2819207?resultClick=3&utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8wdlDo3PCnmaXw2FvvSkY66bGgq0yfMJlu1nNyTAWWdAJfnG30SWffK78IAIrL_-9Tp4hJPHKjAMuYi9KWWu-h3dX6_w&_hsmi=309503763&utm_content=309503763&utm_source=hs_email Preeclampsia is associated with increased risk of young-onset dementia A large study published on Thursday in JAMA Network Open analyzed all the nearly 2 million patients who delivered children in France between 2010 and 2018, finding that pregnant people who developed preeclampsia, a disorder that manifests as high blood pressure during pregnancy, were more likely to develop young-onset dementia. Earlier studies have linked cognitive function impairments with preeclampsia, but this is the first time researchers found an association specifically with early-onset dementia. Patients who developed early dementia tended to be older (delivering at 36.4 years on average, compared to 34.6 for the larger group). Social deprivation, smoking, and diabetes were also associated with increased risk. And risk was higher in pregnant people who developed preeclampsia before 34 weeks of gestation, or already had other forms of hypertension.