Gut Microbiome May Shape Hormone-Dependent Cancers Laurence Salmon

https://www.medscape.com/viewarticle/gut-microbiome-may-shape-hormone-dependent-cancers-2026a1000zrw?ecd=wnl_tp10_daily_260926_MSCPEDIT_etid8728689&uac=148436CN&impID=8728689 Key Takeaways In hormone-dependent cancers, the role of the microbiome in estrogen metabolism (the estrobolome) extends to an endocrine-microbiota axis based on reciprocal interactions with the endocrine system. Several mechanisms, including dysbiosis and chronic inflammation, may promote carcinogenesis. Modulation of the microbiome represents a promising — though still experimental — therapeutic approach.