https://www.medscape.com/viewarticle/diclofenac-did-not-reduce-chemo-induced-hand-foot-syndrome-2026a1000w53?src=
Prophylactic topical diclofenac does not reduce clinically significant hand-foot syndrome (HFS) in patients receiving capecitabine-based therapy, a new real-world observational study found. Grade ≥ 2 HFS occurred in approximately 17% vs 14% of patients using diclofenac gel vs those under active monitoring, with no difference in time to onset.
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