Tumor-intrinsic kinome landscape of pancreatic cancer reveals new therapeutic approaches. +++++++++

https://read.qxmd.com/read/39632628/tumor-intrinsic-kinome-landscape-of-pancreatic-cancer-reveals-new-therapeutic-approaches?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug Tumor-intrinsic kinome landscape of pancreatic cancer reveals new therapeutic approaches. Effective therapies for pancreatic ductal adenocarcinoma (PDAC) have been largely elusive. Here, we perform Multiplexed kinase Inhibitor Bead Mass Spectrometry .. Dec 5, 2024: Cancer Discovery Head-to-head comparison of palbociclib and ribociclib in first-line treatment of HR-positive/HER2-negative metastatic breast cancer with real-world data from the OPAL registry. Marc Thill, Mark-Oliver Zahn, Anja Welt, Arnd Nusch, Matthias Zaiss, Kathrin Engelken, Gabriele Kaltenecker, Kai Ringwald, Katja Gratzke, Stephanie Dille, Lisa Kruggel, Martina Jänicke, Holger Schulz, Volker Hagen, Roland Fricker, Elmar Stickeler, Nadia Harbeck, Achim Wöckel, Thomas Decker International Journal of Cancer. Journal International du Cancer 2024 December 20 https://read.qxmd.com/read/39707595/head-to-head-comparison-of-palbociclib-and-ribociclib-in-first-line-treatment-of-hr-positive-her2-negative-metastatic-breast-cancer-with-real-world-data-from-the-opal-registry?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug Breaking the mold: Unconventional T cells in cancer therapy. Yan-Ruide Li, Kuangyi Zhou, Yichen Zhu, Tyler Halladay, Lili Yang Cancer Cell 2024 December 6 https://read.qxmd.com/read/39672171/breaking-the-mold-unconventional-t-cells-in-cancer-therapy?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug Angioedema. Gina Lacuesta, Stephen D Betschel, Ellie Tsai, Harold Kim Allergy, Asthma, and Clinical Immunology 2024 December 9 https://read.qxmd.com/read/39654054/angioedema?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug The effects of low-dose morphine on sleep and breathlessness in COPD: A randomized trial. Thomas James Altree, Alison Pinczel, Barbara Toson, Kelly Loffler, Anna Hudson, Jim Zeng, Simon Proctor, Ganesh Naik, Sutapa Mukherjee, Peter Catcheside, Andrew Somogyi, David Currow, Danny Eckert Chest 2024 December 13 https://read.qxmd.com/read/39675518/the-effects-of-low-dose-morphine-on-sleep-and-breathlessness-in-copd-a-randomized-trial?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug Potential of Sodium-Glucose Cotransporter-2 Inhibitors in the Management of Heart Failure With Preserved Ejection Fraction: A Narrative Review. Abdulaziz F Alsuwayh, Mohammed Altawili, Marwan Fahad Alhazmi, Dhuha Faisal M Alotaibi, Alghamdi Omar Rashed, Alharbi Hussam Obaid Abdullah, Ahad Ahmad N Alkenani, Rudayna Adel S Almohammdi, Hamad Fahad M Alotaibi, Fatima Essamaldin Altahir Mohamed Alsharif Curēus 2024 November https://read.qxmd.com/read/39697908/potential-of-sodium-glucose-cotransporter-2-inhibitors-in-the-management-of-heart-failure-with-preserved-ejection-fraction-a-narrative-review?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug CAR T-cells in autoimmunity: game changer or stepping stone? Dimitrios Mougiakakos, Everett Meyer, Georg Schett Blood 2024 December 19 https://read.qxmd.com/read/39700499/car-t-cells-in-autoimmunity-game-changer-or-stepping-stone?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug Antibiotic Treatment of Infections Caused by AmpC-Producing Enterobacterales. Gianpiero Tebano, Irene Zaghi, Monica Cricca, Francesco Cristini Pharmacy (Basel, Switzerland) 2024 September 21 https://read.qxmd.com/read/39311133/antibiotic-treatment-of-infections-caused-by-ampc-producing-enterobacterales?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug Exploiting bacteria for cancer immunotherapy. Seong-Young Kwon, Hien Thi-Thu Ngo, Jinbae Son, Yeongjin Hong, Jung-Joon Min Nature Reviews. Clinical Oncology 2024 August https://read.qxmd.com/read/38840029/exploiting-bacteria-for-cancer-immunotherapy?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug

No, Diet and Exercise Are Not Better Than Drugs for Obesity Yoni Freedhoff, MD ++++++

No, Diet & Exercise Are Not Better Than Obesity Drugs No, Diet and Exercise Are Not Better Than Drugs for Obesity Yoni Freedhoff, MD https://www.medscape.com/viewarticle/no-diet-and-exercise-are-not-better-than-drugs-obesity-2024a1000mgl?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891 Injectable Weight Loss Drugs & Environmental Issues Injectable Weight Loss Drugs: Lifestyle Change for the Environment? Arthur L. Caplan, PhD https://www.medscape.com/viewarticle/injectable-weight-loss-drugs-lifestyle-change-environment-2024a1000msg?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891 The Easiest Diet Ever The Easiest Diet Ever Tamaan K. Osbourne-Roberts, MD, MBA https://www.medscape.com/viewarticle/easiest-diet-ever-2024a1000lau?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891 Focus on Nutrient Density, Not Limiting Foods Focus on Nutrient Density Instead of Limiting Certain Foods Brandy Winfree Root, RDN https://www.medscape.com/viewarticle/focus-nutrient-density-instead-limiting-certain-foods-2024a1000lob?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891 Secret to Maintaining Weight Loss With GLP-1s Maintaining Weight Loss With GLP-1s Needs Lifestyle Changes Anne L. Peters, MD https://www.medscape.com/viewarticle/maintaining-weight-loss-glp-1s-needs-lifestyle-changes-2024a1000ld0?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891 Time-Restricted Eating May Improve Metabolic Syndrome Time-Restricted Eating May Help Adults With Metabolic Syndrome Improve Several Health Markers Lisa M. Basile https://www.medscape.com/viewarticle/time-restricted-eating-may-help-adults-metabolic-syndrome-2024a1000hy7?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891

RARE REV-inar episode 015: Complexities of genetic diagnosis of mitochondrial diseases 16 ene 2025 12:00 p. m.

https://us02web.zoom.us/webinar/register/WN_X5Dwp1NYR6idBch3K5yLtw#/registration What role have international organizations played in advancing mitochondrial disease advocacy? How has the collaboration between patient advocacy groups and researchers impacted the field? Join our next RARE Rev-inar on January 26th 2025

How Many Young Breast Cancer Survivors Struggle Financially? Edited by Gargi Mukherjee ++++

PATIENT OUTCOMES Preventive Surgeries Help Young BRCA Patients: New Data Do Risk-Reducing Surgeries Benefit BRCA Carriers With Early-Onset Breast Cancer History? Megan Brooks https://www.medscape.com/viewarticle/do-risk-reducing-surgeries-benefit-brca-carriers-early-onset-2024a1000myt?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120 Unique Challenges, Top Concerns of Young Patients With CRC Identified What Matters Most for Young Patients With CRC: Survey Highlights Top Concerns Megan Brooks https://www.medscape.com/viewarticle/what-matters-most-young-patients-crc-survey-highlights-top-2024a1000ki2?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120 CAR T for B-ALL: Game Changer for Young Patients? CAR T for B-ALL: Game Changer for Young Patients? Randy Dotinga https://www.medscape.com/s/viewarticle/car-t-b-all-game-changer-young-patients-2024a1000aq2?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120 Financial Struggles of Young Breast Cancer Survivors How Many Young Breast Cancer Survivors Struggle Financially? Edited by Gargi Mukherjee https://www.medscape.com/viewarticle/how-many-young-breast-cancer-survivors-struggle-financially-2024a1000mg4?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120

Babies born in 2025 will begin Gen Beta, a brand-new generation Gen Beta, born between 2025 and 2039, will be 'shaped by an entirely different world,' experts predict Angelica Stabile By Angelica Stabile Fox News Published January 1, 2025 10:00am EST

Babies born in 2025 will begin Gen Beta, a brand-new generation Gen Beta, born between 2025 and 2039, will be 'shaped by an entirely different world,' experts predict Angelica Stabile By Angelica Stabile Fox News Published January 1, 2025 10:00am EST https://www.foxnews.com/health/babies-born-2025-begin-gen-beta-brand-new-generation

miércoles, 1 de enero de 2025

Stress

https://www.nccih.nih.gov/health/stress?nav=govd Stress is a physical and emotional reaction that people experience as they encounter challenges in life. When you’re under stress, your body reacts by releasing hormones that produce the “fight-or-flight” response. Your heart rate, breathing rate, and blood pressure go up, your muscles tense, and you sweat more. Occasional stress is a normal coping mechanism. However, long-term stress (also called chronic stress) may contribute to or worsen a range of health problems including digestive disorders, headaches, sleep disorders, and other symptoms. Stress may worsen asthma and has been linked to depression, anxiety, and other mental illnesses. https://files.nccih.nih.gov/press-reset-on-stress-flyer.pdf