RARE DISEASE LEARNING CENTERS ++++ +++++++++

RARE DISEASE LEARNING CENTERS Neuroblastoma https://checkrare.com/neuroblastoma/ Neuroblastoma is a rare childhood cancer, but it is the most common extracranial solid tumor in children. It is a neuroendocrine tumor that originates in neuroblasts or neural crest progenitor cells. Rett Syndrome https://checkrare.com/rett-syndrome/ Rett syndrome is a multisystem disorder that primarily affects girls. Only in rare cases are boys affected (who may experience more severe symptoms). Multiple loss-of-function mutations to the MECP2 gene are the cause of Rett syndrome. Cutaneous T-Cell Lymphoma (CTCL) https://checkrare.com/cutaneous-t-cell-lymphoma-2/ Cutaneous T-cell lymphoma (CTCL) belongs to the non-Hodgkin lymphoma class of hematologic T-cell lymphoproliferative disorders. Tenosynovial Giant Cell Tumor (TGCT) https://checkrare.com/tenosynovial-giant-cell-tumor-tgct/ Tenosynovial giant cell tumor (TGCT) is a non-malignant tumor involving the joint synovium, bursae, and tendon sheath. These rare tumors are sometimes referred to as giant cell tumor of the tendon sheath (GCT-TS) and/or pigmented villonodular synovitis (PVNS). CME PROGRAMS Case Studies in Diagnosing and Managing FOP Christiaan Scott, MD, Professor of Pediatric Rheumatology at the University of Ottawa and Raphaella Stander, MBCHB, Pediatrician at Atlantic Children’s Practice, focused on three case studies to provide physicians with education on best practices to: 1) suspect and diagnose FOP, 2) monitor and manage younger children with FOP, and 3) monitor and manage older children and adults with FOP. https://checkrare.com/learning/p-case-studies-in-diagnosing-and-managing-fop/ CREDITS: 1.0 CME | DURATION: 1.0 hours EXPIRES: 10/1/2026 | FEE: $0 ITP Clinical Research Highlights: ISTH 2025 Shruti Chaturvedi, MD, Assistant Professor of Medicine at Johns Hopkins, describes the latest research being presented to better manage individuals with ITP and its clinical relevance. https://checkrare.com/learning/p-isth2025-module2-immune-thrombocytopenia-clinical-research-highlights/ CREDITS: 0.50 CME | DURATION: 0.50 hours EXPIRES: 9/15/2026 | FEE: $0 Hemophilia Clinical Research Highlights: ISTH 2025 Steven Pipe, MD, Professor of Medicine at the University of Michigan describes the latest research being presented to better manage individuals with hemophilia and its clinical relevance. https://checkrare.com/learning/p-isth2025-module1-hemophilia-clinical-research-highlights/ CREDITS: 0.75 CME | DURATION: 0.75 hours EXPIRES: 9/15/2026 | FEE: $0 iTTP Clinical Research Highlights: ISTH 2025 Shruti Chaturvedi, MD, Assistant Professor of Medicine at Johns Hopkins, describes the latest research being presented to better manage individuals with iTTP and its clinical relevance. https://checkrare.com/learning/p-isth2025-module3-immune-thrombotic-thrombocytopenic-purpura-ittp-clinical-research-highlights/ CREDITS: 0.50 CME | DURATION: 0.50 hours EXPIRES: 9/15/2026 | FEE: $0 Myasthenia Gravis Clinical Research Highlights: AAN 2025 James F. Howard Jr, MD, provides a summary of clinically relevant data presented at AAN 2025 that can enhance the care of patients with myasthenia gravis. https://checkrare.com/learning/p-myasthenia-gravis-clinical-research-highlights-aan-2025/ CREDITS: 0.75 CME | DURATION: 0.75 hours EXPIRES: 8/31/2026 | FEE: $0 Skeletal Involvement in Lysosomal Disorders https://checkrare.com/learning/p-skeletal-involvement-in-lysosomal-disorders/ Ozlem Goker-Alpan, MD, Founder and President, Lysosomal & Rare Disorders Research & Treatment Center (LDRTC) and Ravi Kamath, MD, PhD, of Fairfax Radiological Consultants & Inova Health System and University of Virginia School of Medicine Fairfax, Virginia, USA discuss best practices to identify and treat bone problems associated with lysosomal disorders. CREDITS: 1.0 CME | DURATION: 1.0 hours EXPIRES: 6/30/2026 | FEE: $0 Fabry Disease Research Highlights Eric Wallace, MD, provides a summary of clinically relevant data presented at WORLDSymposium 2025 that can enhance the care of patients with Fabry disease. https://checkrare.com/learning/p-fabry-disease-research-highlights-2025/ CREDITS: 0.5 CME | DURATION: 0.5 hours EXPIRES: 5/15/2026 | FEE: $0 Transforming Clinical Outcomes with Early Treatment of Lysosomal Disorders Ozlem Goker-Alpan MD, David F. Kronn, MD, Uma Ramaswami FRCPCH, MD, Liz Jalazo, MD, and Lindsay Torrice MSN, CPNP-PC, examine the evidence available to address how to monitor, and possibly treat, children with lysosomal diseases that were diagnosed by newborn screening or soon after birth. https://checkrare.com/learning/p-transforming-clinical-outcomes-with-early-treatment-of-lysosomal-disorders/ CREDITS: 1.00 CME | DURATION: 1 hour EXPIRES: 4/03/2026 | FEE: $0 Consider Rare: Suspecting and Diagnosing Hereditary Angioedema Jonathan A Bernstein, MD, describes the early symptoms of HAE and its clinical relevance, and discusses best practices to diagnose HAE more efficiently to reduce diagnostic delays. https://checkrare.com/learning/p-consider-rare-suspecting-and-diagnosing-hereditary-angioedema/ CREDITS: 0.50 CME | DURATION: 30 minutes EXPIRES: 3/15/2026 | FEE: $0