CLINICAL PERSPECTIVES ++++ ++++ ++++

CLINICAL PERSPECTIVES ORIGIN 3 Clinical Trial Evaluating Atacicept in Adults With IgA Nephropathy https://checkrare.com/origin-3-clinical-trial-evaluating-atacicept-in-adults-with-iga-nephropathy/ Richard Lafayette, MD, Professor of Medicine at Stanford University, discusses the ORIGIN clinical trial evaluating atacicept in adults with IgA nephropathy (IgAN). The Use of Nipocalimab in Adolescent Patients With Generalized Myasthenia Gravis https://checkrare.com/the-use-of-nipocalimab-in-adolescent-patients-with-generalized-myasthenia-gravis/ Jonathan Strober, MD, pediatric neurologist and neuromuscular specialist at the University of California at San Francisco, discusses the use of nipocalimab in adolescent patients with generalized myasthenia gravis (gMG). Positive Topline Results from the CALIBRATE Trial of Encaleret in Patients With Autosomal Dominant Hypocalcemia Type 1 https://checkrare.com/positive-topline-results-from-the-calibrate-trial-of-encaleret-in-patients-with-autosomal-dominant-hypocalcemia-type-1/ Michael A. Levine, MD, ML, Children’s Hospital of Philadelphia, discusses positive topline results from the CALIBRATE trial of encaleret in patients with autosomal dominant hypocalcemia type 1 (ADH1). EPIC Clinical Trial Design: Evaluating Nipocalimab Versus Efgartigimod in Patients With Myasthenia Gravis https://checkrare.com/epic-clinical-trial-design-evaluating-nipocalimab-versus-efgartigimod-in-patients-with-myasthenia-gravis/ Nolan Campbell, PhD, U.S. Medical Director at Johnson & Johnson, discusses the EPIC clinical trial design that will evaluate the efficacy of nipocalimab versus efgartigimod in patients with generalized myasthenia gravis (gMG). Efficacy of Nipocalimab in Generalized and Ocular gMG: Long-Term Outcomes and Phase 3 VIVACITY-MG3 Findings https://checkrare.com/efficacy-of-nipocalimab-in-generalized-and-ocular-gmg-long-term-outcomes-and-phase-3-vivacity-mg3-findings/ Sindhu Ramchandren, MD, Executive Medical Director of Neuroscience at Johnson & Johnson, discusses long-term efficacy of nipocalimab in patients with generalized myasthenia gravis (gMG). Ongoing Phase 3 Study of Paltusotine in Carcinoid Syndrome Due to Neuroendocrine Tumors https://checkrare.com/ongoing-phase-3-study-of-paltusotine-in-carcinoid-syndrome-due-to-neuroendocrine-tumors/ Aman Chauhan, MD, Oncologist at the University of Miami, discusses details of a phase 3 study testing paltusotine in patients with carcinoid syndrome due to neuroendocrine tumors (NETs). The Shift to Precision Medicine in Myasthenia Gravis https://checkrare.com/the-shift-to-precision-medicine-in-myasthenia-gravis/ Alexandra C. Bayer Wildberger, PhD, Post-Doctoral Associate at Yale School of Medicine, discusses the shift to precision medicine in myasthenia gravis (MG). Long-Term Data From the AQUARIUS Study of Avacopan in Patients With GPA and MPA https://checkrare.com/long-term-data-from-the-aquarius-study-of-avacopan-in-patients-with-gpa-and-mpa/ Naomi Patel, MD, MPH, Rheumatologist at Massachusetts General Hospital, discusses long-term data from the AQUARIUS study of avacopan in patients with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). Data on the RAISE Clinical Trial Program of Zilucoplan for the Treatment of Myasthenia Gravis https://checkrare.com/data-on-the-raise-clinical-trial-program-of-zilucoplan-for-the-treatment-of-myasthenia-gravis/ Michael Weiss, MD, Neurologist at the University of Washington, discusses data on the RAISE and RAISE-XT clinical trials of zilucoplan for the treatment of generalized myasthenia gravis (gMG). New Data on Vyvgart for Patients With AChR-Ab Seronegative Myasthenia Gravis https://checkrare.com/new-data-on-vygart-for-patients-with-achr-ab-seronegative-myasthenia-gravis/ James Howard, Jr., MD, Professor of Neurology at the University of North Carolina, discusses new data on the safety and efficacy of Vyvgart (efgartigimod alfa) for patients with AChR-Ab seronegative generalized myasthenia gravis (gMG). A Patient’s Diagnostic Journey With Systemic Mastocytosis https://checkrare.com/a-patients-diagnostic-journey-with-systemic-mastocytosis/ Joan Smith, patient with systemic mastocytosis, discusses her diagnostic journey with systemic mastocytosis (SM). Results From the DeFi Clinical Trial of Nirogacestat in Patients With Desmoid Tumors https://checkrare.com/results-from-the-defi-clinical-trial-of-nirogacestat-in-patients-with-desmoid-tumors/ Bernd Kasper, MD, PhD, University of Heidelberg Cancer Center, discusses results from the DeFi clinical trial of nirogacestat in patients with desmoid tumors.