DKK1 identified as key driver of immune resistance in bone metastases +++

DKK1 identified as key driver of immune resistance in bone metastases https://www.news-medical.net/news/20250807/DKK1-identified-as-key-driver-of-immune-resistance-in-bone-metastases.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_13_august_2025 Many major cancers, including those of the lung, breast and prostate gland, spread to the bones as they progress. Tokyo researchers reveal key role of Fen1 in resisting antiviral and anticancer drug effects https://www.news-medical.net/news/20250810/Tokyo-researchers-reveal-key-role-of-Fen1-in-resisting-antiviral-and-anticancer-drug-effects.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_13_august_2025 Researchers from Tokyo Metropolitan University have discovered a new pathway by which cells counteract the action of alovudine, an important antiviral and anticancer drug. Study links baseline fatigue with higher inflammation in breast cancer survivors https://www.news-medical.net/news/20250812/Study-links-baseline-fatigue-with-higher-inflammation-in-breast-cancer-survivors.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_13_august_2025 For many breast cancer survivors, fatigue may linger long after treatment ends, which can have a significant impact on cognitive function, ability to work, and overall quality of life.