US DRUG SPOTLIGHT +++

US DRUG SPOTLIGHT Enzalutamide enzalutamide (Rx) https://reference.medscape.com/drug/xtandi-enzalutamide-999769?ecd=mkm_ret_241231_mscpmrk_onc_top-content_etid7132666&uac=148436CN&impID=7132666 Ibrutinib ibrutinib (Rx)https://reference.medscape.com/drug/imbruvica-ibrutinib-999896?ecd=mkm_ret_241231_mscpmrk_onc_top-content_etid7132666&uac=148436CN&impID=7132666 Atezolizumab atezolizumab (Rx) https://reference.medscape.com/drug/tecentriq-atezolizumab-1000098?ecd=mkm_ret_241231_mscpmrk_onc_top-content_etid7132666&uac=148436CN&impID=7132666

Tattoos May Be Risk Factors for Malignant Lymphoma Miriam Davis | +++++

EMERGING RISK FACTORS Tattoos Linked to Malignant Lymphoma Tattoos May Be Risk Factors for Malignant Lymphoma Miriam Davis | https://www.medscape.co.uk/viewarticle/tattoos-may-be-risk-factors-malignant-lymphoma-2024a10009sf?ecd=mkm_ret_241231_mscpmrk_onc_top-content_etid7132666&uac=148436CN&impID=7132666&sso=true Eye Toxicities a Growing Concern With Certain ADCs Eye Toxicities Are a Growing Concern With Certain ADCs Liam Davenport https://www.medscape.com/viewarticle/eye-toxicities-are-growing-concern-certain-adcs-2024a1000mvw?ecd=mkm_ret_241231_mscpmrk_onc_top-content_etid7132666&uac=148436CN&impID=7132666 December 11, 2024 Does Quitting Alcohol Lower Cancer Risk? Does Eliminating Alcohol Intake Lower Cancer Risk? Sharon Worcester, MA https://www.medscape.com/viewarticle/does-eliminating-alcohol-intake-lower-cancer-risk-2024a10002kz?ecd=mkm_ret_241231_mscpmrk_onc_top-content_etid7132666&uac=148436CN&impID=7132666 What’s Driving Lung Cancer in Never-Smokers? Climate Change May Be Linked to Lung Cancer in Never-Smokers Sharon Worcester https://www.medscape.com/viewarticle/climate-change-may-be-linked-lung-cancer-never-smokers-2024a1000jif?ecd=mkm_ret_241231_mscpmrk_onc_top-content_etid7132666&uac=148436CN&impID=7132666 Silent Threat Steps Into the Limelight CHIP: The Silent Threat Steps Into the Limelight Liam Davenport https://www.medscape.com/viewarticle/chip-silent-threat-steps-limelight-2024a1000591?ecd=mkm_ret_241231_mscpmrk_onc_top-content_etid7132666&uac=148436CN&impID=7132666

Imperfect JOY: Capturing the Lives of Patients With Rare Diseases By: Madaline Spencer| // Addressing Mental Health in Patients with Rare Diseases By: Madaline Spencer| // Addressing Unmet Needs in Rare Diseases By: Madaline Spencer| // Undiagnosed Diseases Network Foundation: Providing Resources and Support for Undiagnosed Community By: Madaline Spencer| // ++++

Imperfect JOY: Capturing the Lives of Patients With Rare Diseases https://checkrare.com/imperfect-joy-capturing-the-lives-of-patients-with-rare-diseases/ Melody Joy Paine, founder of Imperfect JOY, discusses how she captures the lies of patients with rare diseases through photography and filmmaking. Addressing Mental Health in Patients with Rare Diseases https://checkrare.com/addressing-mental-health-in-patients-with-rare-diseases/ David Gusick, Founder of Somebody To Talk To, discusses mental health in patients with rare diseases. Addressing Unmet Needs in Rare Diseases https://checkrare.com/addressing-unmet-needs-in-rare-diseases/ Cathleen Lutz, PhD, Vice President of the Rare Disease Translational Center at The Jackson Laboratory (JAX), discusses how the laboratory is addressing unmet needs in rare diseases. Undiagnosed Diseases Network Foundation: Providing Resources and Support for Undiagnosed Community https://checkrare.com/undiagnosed-diseases-network-foundation-providing-resources-and-support-for-undiagnosed-community/ Amy Gray, Chief Executive Officer of the Undiagnosed Diseases Network Foundation (UDNF), discusses the organization and what they do for patients of undiagnosed rare diseases.

Expert Tips for Managing GLP-1 Medication Side Effects Sara Novak December 27, 2024 +++++

Latest Stories Managing GLP-1 Side Effects: Expert Tips Expert Tips for Managing GLP-1 Medication Side Effects Sara Novak https://www.medscape.com/viewarticle/expert-tips-managing-glp-1-medication-side-effects-2024a1000p8l?ecd=mkm_ret_241228_mscpmrk_MOB_e10_etid7124123&uac=148436CN&impID=7124123 December 27, 2024 Is Oral XEN-D0501 the Next Obesity Drug Hype? Is Oral XEN-D0501 the Next Obesity Drug Hype? Manuela Callari https://www.medscape.com/viewarticle/oral-xen-d0501-next-obesity-drug-hype-2024a1000osr?ecd=mkm_ret_241228_mscpmrk_MOB_e10_etid7124123&uac=148436CN&impID=7124123 December 20, 2024 Six Substudies From the Semaglutide Trials Six Substudies From the Semaglutide Trials: Identifying Mechanisms of Benefit and Whom to Treat Identifying Mechanisms of Benefit and Whom to Treat Neha J. Pagidipati, MD, MPH https://www.medscape.com/s/viewarticle/1001953?ecd=mkm_ret_241228_mscpmrk_MOB_e10_etid7124123&uac=148436CN&impID=7124123 Weight Loss Drugs Could Help End Obesity - but Risks Remain Weight Loss Drugs Could Help End Obesity - but Risks Remain, WHO Says Jennifer Rigby https://www.medscape.com/s/viewarticle/weight-loss-drugs-could-help-end-obesity-risks-remain-who-2024a1000nrn?ecd=mkm_ret_241228_mscpmrk_MOB_e10_etid7124123&uac=148436CN&impID=7124123 December 18, 2024 Injectable Weight Loss Drugs: Lifestyle Change for the Environment? Injectable Weight Loss Drugs: Lifestyle Change for the Environment? Arthur L. Caplan, PhD https://www.medscape.com/viewarticle/injectable-weight-loss-drugs-lifestyle-change-environment-2024a1000msg?ecd=mkm_ret_241228_mscpmrk_MOB_e10_etid7124123&uac=148436CN&impID=7124123

HELPING HUTT LIVE HIS BEST LIFE

Helping Hutt Live His Best Life with TAR Syndrome By Ivanhoe Broadcast News on December 31, 2024 https://www.ivanhoe.com/?p=34810&preview=1&_ppp=3b85ef908b

NEW OPTIONS TO DETECT AND TREAT OVARIAN CANCER

New Options to Detect and Treat Ovarian Cancer By Ivanhoe Broadcast News on December 30, 2024 https://www.ivanhoe.com/?p=34807&preview=1&_ppp=a8493f5c3c

The year in cancer: Advances made in 2024, predictions for 2025 4 cancer experts reveal important progress and look ahead to future developments Melissa Rudy By Melissa Rudy Fox News Published December 23, 2024 4:30am EST | Updated December 23, 2024 6:31am EST

The year in cancer: Advances made in 2024, predictions for 2025 4 cancer experts reveal important progress and look ahead to future developments Melissa Rudy By Melissa Rudy Fox News Published December 23, 2024 4:30am EST | Updated December 23, 2024 6:31am EST https://www.foxnews.com/health/year-cancer-advances-made-2024-predictions-2025

FDA approves first medication for obstructive sleep apnea, which also promotes weight loss Eli Lilly's Zepbound treats moderate to severe cases of the sleep disorder in adults with obesity: 'Promising advancement' Angelica Stabile By Angelica Stabile Fox News Published December 24, 2024 10:55am EST

FDA approves first medication for obstructive sleep apnea, which also promotes weight loss Eli Lilly's Zepbound treats moderate to severe cases of the sleep disorder in adults with obesity: 'Promising advancement' Angelica Stabile By Angelica Stabile Fox News Published December 24, 2024 10:55am EST https://www.foxnews.com/health/fda-approves-first-medication-obstructive-sleep-apnea-also-promotes-weight-loss

Pregnant woman and baby saved after doctors find grapefruit-sized tumor: 'Extremely rare' Young Chicago mother says she's ‘still healing,’ thanks medical team for ‘wonderful care’ Melissa Rudy By Melissa Rudy Fox News Published December 25, 2024 4:30am EST

Pregnant woman and baby saved after doctors find grapefruit-sized tumor: 'Extremely rare' Young Chicago mother says she's ‘still healing,’ thanks medical team for ‘wonderful care’ Melissa Rudy By Melissa Rudy Fox News Published December 25, 2024 4:30am EST https://www.foxnews.com/health/pregnant-woman-baby-saved-doctors-find-grapefruit-sized-tumor-rare

Restless Legs Syndrome: What to Know in Primary Care Kevin Fernando, MBChB ++++++ Most Listened of 2024

https://www.medscape.com/viewarticle/1000614?ecd=mkm_ret_241226_mscpmrk-OUS_InFocus_etid7100602&uac=148436CN&impID=7100602 Food Is Not Medicine but Maybe It's Healthcare Food Is Not Medicine but Maybe It's Healthcare Robert A. Harrington, MD; Mitchell S.V. Elkind, MD, MS, MPhil https://www.medscape.com/viewarticle/1000199?ecd=mkm_ret_241226_mscpmrk-OUS_InFocus_etid7100602&uac=148436CN&impID=7100602 Coronary Artery Disease: The New Big C Coronary Artery Disease: The New Big C Robert A. Harrington, MD; Michael V. McConnell, MD, MSEE https://www.medscape.com/viewarticle/999964?ecd=mkm_ret_241226_mscpmrk-OUS_InFocus_etid7100602&uac=148436CN&impID=7100602 Understanding, Detecting, and Treating GEJ Adenocarcinoma Understanding, Detecting, and Treating Gastroesophageal Junction Adenocarcinoma Samuel J. Klempner, MD; Yelena Y. Janjigian, MD https://www.medscape.com/viewarticle/999882?ecd=mkm_ret_241226_mscpmrk-OUS_InFocus_etid7100602&uac=148436CN&impID=7100602 COPD Case Study: Pearls for Diagnosis & Initial Management COPD Case Study: Pearls for Diagnosis and Initial Management Leah J. Witt, MD; Stephanie A. Christenson, MD, MAS https://www.medscape.com/viewarticle/999789?ecd=mkm_ret_241226_mscpmrk-OUS_InFocus_etid7100602&uac=148436CN&impID=7100602 This Week in Cardiology: Plastics & Heart Disease Mar 08, 2024 This Week in Cardiology Podcast John M. Mandrola, MD https://www.medscape.com/viewarticle/1000359?ecd=mkm_ret_241226_mscpmrk-OUS_InFocus_etid7100602&uac=148436CN&impID=7100602

Division of Discovery Science and Technology (Bioengineering)

Division of Discovery Science and Technology (Bioengineering): This program supports cross-cutting discovery engineering and applied science projects that advance the science and engineering related to the development of broadly applicable biomedical technologies

Biomaterial Technologies

Biomaterial Technologies: In medical devices as simplistic as dental fillings to as complex as spinal cord stimulators, biomaterials interact with the human body to fulfill medical needs

Engineering a smile

Engineering a smile: With the help of some of nature’s best engineers, NIBIB-funded researchers have developed technology to regrow damaged facial nerves.

Building a multilayered drug delivery system that’s activated by ultrasound

Building a multilayered drug delivery system that’s activated by ultrasound: Releasing a drug selectively in specific locations in the body, including the brain, has been challenging. Researchers at the University of Utah have tackled the problem by designing ultrasound-sensitive nanoparticles that release a drug at the targeted site when activated by focused ultrasound.

OH MY ACHING HEAD! RELIEVING PATRICE’S PAIN

Oh My Aching Head! Relieving Patrice’s Pain By Ivanhoe Broadcast News on December 25, 2024 https://www.ivanhoe.com/?p=34780&preview=1&_ppp=f544377cd3

SWEET DREAMS: MEETING THE NEEDS OF HISPANIC COMMUNITY

Sweet Dreams: Meeting the Needs of Hispanic Community By Ivanhoe Broadcast News on December 26, 2024 https://www.ivanhoe.com/?p=34783&preview=1&_ppp=c34382ee4b

THE CLIMATE CONVERSATION: A DIFFICULT DISCUSSION WITH TEENS

The Climate Conversation: A Difficult Discussion with Teens By Ivanhoe Broadcast News on December 28, 2024 https://www.ivanhoe.com/?p=34761&preview=1&_ppp=62f0437366

AIR POLLUTION & CHILDREN’S HEALTH: LITTLE LUNGS, BIG PROBLEM

Air Pollution & Children’s Health: Little Lungs, Big Problem By Ivanhoe Broadcast News on December 28, 2024 https://www.ivanhoe.com/?p=34764&preview=1&_ppp=175a295890

Study shows beef can be part of a heart-healthy diet

https://www.news-medical.net/news/20241220/Study-shows-beef-can-be-part-of-a-heart-healthy-diet.aspx

FDA adds warning about rare occurrence of serious liver injury with use of Veozah (fezolinetant) for hot flashes due to menopause Stop medicine if signs and symptoms of liver injury occur

FDA adds warning about rare occurrence of serious liver injury with use of Veozah (fezolinetant) for hot flashes due to menopause Stop medicine if signs and symptoms of liver injury occur https://www.fda.gov/drugs/drug-safety-and-availability/fda-adds-warning-about-rare-occurrence-serious-liver-injury-use-veozah-fezolinetant-hot-flashes-due?utm_medium=email&utm_source=govdelivery HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use VEOZAH safely and effectively. See full prescribing information for VEOZAH. VEOZAH® (fezolinetant) tablets, for oral use Initial U.S. Approval: 2023 https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/216578s004lbl.pdf?utm_medium=email&utm_source=govdelivery

viernes, 20 de diciembre de 2024

NIH announces awards to advance tech for HIV viral load detection

NIH announces awards to advance tech for HIV viral load detection: NIH has awarded more than $4 million in funds and support services to three diagnostic technology developers as part of RADx ® Tech’s Advanced Platforms for HIV Viral Load Monitoring program.

Calling for Reinforcements: A New Way to Recruit Immune System Helpers Could Lead to Better Flu Vaccines

Calling for Reinforcements: A New Way to Recruit Immune System Helpers Could Lead to Better Flu Vaccines https://www.niaid.nih.gov/news-events/helper-t-cells-better-flu-vaccines?utm_campaign=+63468942&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term= Each year, flu causes hundreds of thousands of deaths and millions of hospitalizations worldwide. Although the best way to protect against serious illness is annual vaccination, the influenza vaccine’s effectiveness is not perfect. Now, NIH-funded researchers at the Stanford University School of Medicine have taken a new approach to crafting flu vaccines that resulted, both in mice and human tonsil tissue, in a more broadly protective immune response compared to currently available flu vaccines.

What effects does first exposure to social media have on former haredi Jews? The study aimed to look at ex-ultra-Orthodox Jews' use of social media after their first encounter with it to see what effect it had on them. By JERUSALEM POST STAFF DECEMBER 19, 2024 05:46 Updated: DECEMBER 19, 2024 11:25

What effects does first exposure to social media have on former haredi Jews? The study aimed to look at ex-ultra-Orthodox Jews' use of social media after their first encounter with it to see what effect it had on them. By JERUSALEM POST STAFF DECEMBER 19, 2024 05:46 Updated: DECEMBER 19, 2024 11:25 https://www.jpost.com/science/article-834063

Israeli breakthrough: Freeze-dried COVID vaccine needs no refrigeration TAU’s groundbreaking project has received competitive research grants from the Israel Innovation Authority and Merck under the Nofar program. By JUDY SIEGEL-ITZKOVICH DECEMBER 8, 2024 00:04 Updated: DECEMBER 9, 2024 07:32

Israeli breakthrough: Freeze-dried COVID vaccine needs no refrigeration TAU’s groundbreaking project has received competitive research grants from the Israel Innovation Authority and Merck under the Nofar program. By JUDY SIEGEL-ITZKOVICH DECEMBER 8, 2024 00:04 Updated: DECEMBER 9, 2024 07:32 https://www.jpost.com/health-and-wellness/coronavirus/article-832389

The hidden risks of medical cannabis: What to watch for Medical cannabis use in Israel surging, with over 140,000 licenses issued; while offering therapeutic benefits, new study warns of risks like anxiety, reduced quality of life and problematic use, underscoring need for early detection of adverse effects Dr. Daniel Feingold, Or Gliksberg|12.18.24 | 17:43

The hidden risks of medical cannabis: What to watch for Medical cannabis use in Israel surging, with over 140,000 licenses issued; while offering therapeutic benefits, new study warns of risks like anxiety, reduced quality of life and problematic use, underscoring need for early detection of adverse effects Dr. Daniel Feingold, Or Gliksberg|12.18.24 | 17:43 https://www.ynetnews.com/health_science/article/skssfqxrkg

Rediscovering an Extinct Biochemical Reaction A new study has identified an inorganic molecule that likely played a significant role in many of the processes that shaped life as we know it today. Jonathan Berkheim, Davidson Institute of Science|06:01

Rediscovering an Extinct Biochemical Reaction A new study has identified an inorganic molecule that likely played a significant role in many of the processes that shaped life as we know it today. Jonathan Berkheim, Davidson Institute of Science|06:01 https://www.ynetnews.com/health_science/article/byt6nsmrkx

Israeli tech firm helps cut US health-insurance red tape Nym’s AI-powered platform automatically translates notes from patient charts into diagnostic and billing charge codes, without human intervention.

Israeli tech firm helps cut US health-insurance red tape By Yulia Karra Nym’s AI-powered platform automatically translates notes from patient charts into diagnostic and billing charge codes, without human intervention. https://www.israel21c.org/israeli-tech-firm-helps-cut-us-health-insurance-red-tape/

Converge Bio brings GenAI to drug discovery New company in Tel Aviv builds large language models that accelerate research and remove guesswork for biotech and pharma businesses.

Converge Bio brings GenAI to drug discovery By John Jeffay New company in Tel Aviv builds large language models that accelerate research and remove guesswork for biotech and pharma businesses. https://www.israel21c.org/converge-bio-brings-genai-to-drug-discovery/

Biotech startup aims to tackle chronic back pain With new funding 0f $16m, Israeli startup Discure aims to transform degenerative disc disease treatment using innovative implant technology.

Biotech startup aims to tackle chronic back pain By Zachy Hennessey With new funding 0f $16m, Israeli startup Discure aims to transform degenerative disc disease treatment using innovative implant technology. https://www.israel21c.org/biotech-startup-aims-to-tackle-chronic-back-pain/

Israeli hospital rewards innovations from Druze sector Sheba Medical Center’s unique initiative invited budding Druze entrepreneurs to submit their ideas for a chance to secure funding and mentorship.

Israeli hospital rewards innovations from Druze sector By Yulia Karra Sheba Medical Center’s unique initiative invited budding Druze entrepreneurs to submit their ideas for a chance to secure funding and mentorship. https://www.israel21c.org/israeli-hospital-rewards-innovations-from-druze-sector/

The top 12 most amazing Israeli medical advances Israel is a powerhouse in medical innovation. We’ve chosen a dozen standouts from a field with many game-changing candidates.

The top 12 most amazing Israeli medical advances By Abigail Klein Leichman Israel is a powerhouse in medical innovation. We’ve chosen a dozen standouts from a field with many game-changing candidates. https://www.israel21c.org/the-top-12-most-amazing-israeli-medical-advances/

jueves, 19 de diciembre de 2024

Cancer Genetics Risk Assessment and Counseling (PDQ®)–Health Professional Version +++

Cancer Genetics Risk Assessment and Counseling We updated information on Genetic Testing https://www.cancer.gov/publications/pdq/information-summaries/genetics/risk-assessment-hp-pdq?cid=eb_govdel#top Genetics of Endocrine and Neuroendocrine Neoplasias Genetics of Endocrine and Neuroendocrine Neoplasias (PDQ®)–Health Professional Version We updated information on Multiple Endocrine Neoplasia Type 2 https://www.cancer.gov/types/thyroid/hp/medullary-thyroid-genetics-pdq?cid=eb_govdel#top Multiple Endocrine Neoplasia Type 2 (MEN2) (PDQ®)–Health Professional Version Multiple Endocrine Neoplasia Type 2 (MEN2) https://www.cancer.gov/publications/pdq/information-summaries/genetics/men2-hp-pdq?cid=eb_govdel#top This is a new summary.

Are Endocrine Disruptors Really a Threat to Health? Serge Cannasse December 05, 2024 +++++ +++

Latest Stories Are Endocrine Disruptors Really a Threat? Are Endocrine Disruptors Really a Threat to Health? Serge Cannasse https://www.medscape.com/viewarticle/are-endocrine-disruptors-really-threat-health-2024a1000mf4?ecd=mkm_ret_241218_mscpmrk_endo_hormone_etid7096480&uac=148436CN&impID=7096480 December 05, 2024 Do This to Cut Hypothyroidism Rates Adjusting Thyroid Ranges for Age Cuts Hypothyroidism Rates Nancy A. Melville https://www.medscape.com/viewarticle/adjusting-thyroid-ranges-age-cuts-hypothyroidism-rates-2024a1000kzi?ecd=mkm_ret_241218_mscpmrk_endo_hormone_etid7096480&uac=148436CN&impID=7096480 PFAS Exposure Can Impair Thyroid Homeostasis PFAS Exposure Can Impair Thyroid Homeostasis in Adults Edited by Manasi Talwadekar https://www.medscape.com/viewarticle/pfas-exposure-can-impair-thyroid-homeostasis-adults-2024a1000m10?ecd=mkm_ret_241218_mscpmrk_endo_hormone_etid7096480&uac=148436CN&impID=7096480 Hypothyroidism: Examining T4/T3 Combo Therapy Examining T4/T3 Combination Therapy in Hypothyroidism Darcy Lewis https://www.medscape.com/viewarticle/examining-t4-t3-combination-therapy-hypothyroidism-2024a1000l8b?ecd=mkm_ret_241218_mscpmrk_endo_hormone_etid7096480&uac=148436CN&impID=7096480 Transdermal Beats Oral Estrogen for CVD Safety of Hormone Therapy Transdermal Beats Oral Estrogen for CVD Safety of Hormone Therapy JoAnn E. Manson, MD, DrPH https://www.medscape.com/viewarticle/transdermal-beats-oral-estrogen-cvd-safety-hormone-therapy-2024a1000mny?ecd=mkm_ret_241218_mscpmrk_endo_hormone_etid7096480&uac=148436CN&impID=7096480 ICYMI Hyperthyroidism: Evolving Tx Strategies Changing Concepts in Hyperthyroidism Management Darcy Lewis https://www.medscape.com/viewarticle/changing-concepts-hyperthyroidism-management-2024a1000kcl?ecd=mkm_ret_241218_mscpmrk_endo_hormone_etid7096480&uac=148436CN&impID=7096480 Update Coming for Thyroid Disease in Pregnancy Guidelines Update Coming for Thyroid Disease in Pregnancy Guidelines Nancy A. Melville https://www.medscape.com/viewarticle/update-coming-thyroid-disease-pregnancy-guidelines-2024a1000kfm?ecd=mkm_ret_241218_mscpmrk_endo_hormone_etid7096480&uac=148436CN&impID=7096480 Updates on Risk, Diagnosis, & Tx of Thyroid Cancer ATA: Updates on Risk, Diagnosis, and Treatment of Thyroid Cancer Edited by Darcy Lewis https://www.medscape.com/viewarticle/ata-updates-risk-diagnosis-and-treatment-thyroid-cancer-2024a1000k1c?ecd=mkm_ret_241218_mscpmrk_endo_hormone_etid7096480&uac=148436CN&impID=7096480