Targeted next-generation sequencing (NGS) to diagnose drug-resistant tuberculosis: a systematic review and meta-analysis (Posted May 26, 2024 11AM)

https://phgkb.cdc.gov/PHGKB/specificPHGKB.action?topic=Infectious%20diseases&query=home From the abstract: "Targeted NGS is highly sensitive and specific for detecting drug resistance across panels of tuberculosis drugs and can be performed directly on clinical samples. There is a paucity of data on performance for some currently recommended drugs. The barriers preventing the use of targeted NGS to diagnose drug-resistant tuberculosis in high-burden countries need to be addressed. "