A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open-label randomised controlled trial

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00034-7/fulltext?dgcid=hubspot_update_feature_updatealerts_langas&utm_campaign=update-langas&utm_medium=email&_hsenc=p2ANqtz-8DwYFr3b-vp3I0SbYRKbE1O8JjS4M_1Mxr7B_WUFDguSa0yGI2cD5hV0ss1nHfFoW9bxQ2lrhI5o7onYOwAhq1_VW6rg&_hsmi=303970374&utm_content=303954476&utm_source=hs_email