Stem Cell Changes Rejuvenate Immune System in Aged Mice

https://www.niaid.nih.gov/news-events/immune-system?utm_campaign=+59960585&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term= Stem Cell Changes Rejuvenate Immune System in Aged Mice NIAID, Stanford Exploring Potential for Revitalizing Human Immunity Aging is associated with a reduced ability to generate immune responses against novel infections, as was recently illustrated by the high mortality among older people during the COVID-19 pandemic. Using a mouse model of human aging and disease, NIAID scientists and Stanford University colleagues have shown that immune systems of aged laboratory mice can be made more youthful and effective at fighting disease by depleting a subset of haematopoietic stem cells (HSCs). The researchers think the method they developed may have potential for rejuvenating immunity in elderly people and are pursuing further study. Their findings are published in Nature.