Concordance of a High Lipoprotein(a) Concentration Among Relatives. Laurens F Reeskamp et al. JAMA Cardiol 2023 10

From the abstract: "What is the prevalence of high lipoprotein(a) concentrations (=125 nmol/L) in first- and second-degree relatives of individuals with high lipoprotein(a) levels? In this cross-sectional study, 1607 of 3420 (47.0%) first-degree relatives of UK Biobank participants with a lipoprotein(a) concentration at least 125 nmol/L were similarly affected, compared with 4974 of 30 258 (16.4%) unrelated individuals. Cascade screening of first-degree relatives of individuals with high lipoprotein(a) levels, if implemented at scale, is likely to identify a substantial number of additional high-risk individuals. " https://phgkb.cdc.gov/PHGKB/phgHome.action?query=Lipoprotein%20a&action=search&Mysubmit=Search