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What is Time-Resolved Fluorescence Spectroscopy?

Time-resolved fluorescence spectroscopy is a spectroscopy technique used to monitor interactions between molecules and motions that occur in the short periods. The ability to measure changes in the picosecond or nanosecond time range makes it a useful technique in biomolecular structure analysis and dynamics.

			What is Fluorescence Force Microscopy? Fluorescence force microscopy is a combination of atomic force microscopy and fluorescence microscopy, which allows molecular dynamics to be studied. The technique can be applied to single molecules, allowing a more in-depth study of protein folding, for example in cellular dynamics and cell movement.

			Single-Molecule Fluorescence for the Study of GPCRs – Conformational Dynamics A review has addressed GPCR structural dynamics and the role of SMF methods in their interrogation.The team focuses on single-molecule Förster resonance energy transfer (smFRET) in particular, which enables distances and, therefore, conformational changes to be measured across the timescales over which protein conformational movements occur.

	What is Multicolor Flow Cytometry? Scientists use multicolor flow cytometry to identify and characterize targeted cellular subpopulations.

	Quantum Dot for Nano Fluorescent Semiconductors Quantum dots have become a principal topic in nanotechnology, finding applications in varying fields, from renewable energy to medical imaging.

	What is Point Accumulation for Imaging in Nanoscale Topography (PAINT)? Biological systems are incredibly complex, with numerous types of cells working together in tissues and organs, performing processes necessary to sustain life.

	Studying Organelle Diversity using Immunofluorescent Array Tomography Immunofluorescent Array Tomography microscopy allows insight into organelle activity roles in pathologies and diseases.

	Using FMR and TFR-FLIM to Image Matrix Viscosity and Membrane Fluidity A team has pioneered the first combined framework for imaging matrix viscosity and membrane fluidity using FMR and TFR-FLIM.