Medical News | Medical Articles: Translational Challenges Preventing Clinically Effective Neurodegenerative Drug Development

Medical News | Medical Articles

April 30, 2019     Neurology / Neuroscience     The latest neurology news from News Medical

Translational ChallengesPreventing Clinically Effective Neurodegenerative Drug Development NDD Europe (21st – 23rd May, Paris, France) will overcome the translational challenges facing neurodegenerative drug developers by exploring the future biomarkers of neurodegeneration, improving preclinical modelling to increase clinical predictability and encouraging precompetitive strategies and collaboration amongst drug developers. With 70+ thought-leaders converging at NDD Europe, this will be an unrivalled opportunity for you to gain the latest scientific insights, have your peers review your research and grow your collaborator network. Find Out More

Two studies uncover brain mechanisms underlying decision making process   New research conducted in the Cognitive Neuroscience group of SISSA shows that a perceptual decision - recognizing an object and taking the appropriate action - is triggered as soon as the brain's processing networks accumulate the exact right quantity of sensory information.         New chemical synthesis strategy leads to identification of novel, simpler derivatives   A new chemical synthesis strategy to harvest the rich information found in natural products -- organic compounds isolated from natural sources -- has led to the identification of novel, simpler derivatives with potential to selectively protect neurons, important for neurodegenerative diseases like Alzheimer's disease, or to prevent the immune system from rejecting organ transplants, according to a Baylor University-led study.

Advances in deep brain stimulation for Parkinson’s could lead to treatments for other disorders   A new paper published in Nature Reviews Neurology suggests that recent advances in deep brain stimulation for Parkinson disease could lead to treatments for conditions such as obsessive-compulsive disorder, Gilles de la Tourette syndrome and depression.       Electrostimulation can improve working memory of people in their 70s, study shows   In a groundbreaking study published in Nature Neuroscience, Rob Reinhart, an assistant professor of psychological and brain sciences at Boston University and BU doctoral researcher John Nguyen, demonstrate that electrostimulation can improve the working memory of people in their 70s so that their performance on memory tasks is indistinguishable from that of 20-year-olds.       Neuroscientists identify factors for maintaining healthy memory at any age   University of Alberta neuroscientists have identified different factors for maintaining healthy memory and for avoiding memory decline in those over age 55, according to a new study. The results have implications for the prevention of Alzheimer's disease through targeted early intervention efforts.       Brain zaps at 60 could make the brain younger finds study   A new study has shown that zapping the brains of people over the age of 60 can help improve their memory and cognitive functions to function as if they were in their 20s. Researcher Robert Reinhart of Boston University says that this study could pave the way for research in age related dementias such as Alzheimer’s disease. The results of the study titled, “Working memory revived in older adults by synchronizing rhythmic brain circuits,” were published this week in the latest issue of the journal Nature Neuroscience.       Early nutritional intervention can help fight dementia   Trials have revealed significant advantages for patients who are treated with daily medical nutrient drinks, with 45 % less deterioration in the Clinical Dementia Rating Sum of Boxes.       Studies provide new view on the mechanisms of how the brain works   After a series of studies, researchers at Lund University in Sweden, together with colleagues in Italy, have shown that not only one part, but most parts of the brain can be involved in processing the signals that arise from touch.

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