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Cancer & Metabolism

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1. Content Type:Research

     |  17 April 2018

   Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities

   Authors:Matthew Garrett, Jantzen Sperry, Daniel Braas, Weihong Yan, Thuc M. Le, Jack Mottahedeh, Kirsten Ludwig, Ascia Eskin, Yue Qin, Rachelle Levy, Joshua J. Breunig, Frank Pajonk, Thomas G. Graeber, Caius G. Radu, Heather Christofk, Robert M. Prins…
2. Content Type:Research

     |  3 April 2018

   Metabolomics of oncogene-specific metabolic reprogramming during breast cancer

   Authors:Chen Dai, Jennifer Arceo, James Arnold, Arun Sreekumar, Norman J. Dovichi, Jun Li and Laurie E. Littlepage
3. Content Type:Research

     |  3 April 2018

   Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner

   Authors:Pavithra Viswanath, Marina Radoul, Jose Luis Izquierdo-Garcia, Hema Artee Luchman, J. Gregory Cairncross, Russell O. Pieper, Joanna J. Phillips and Sabrina M. Ronen
4. Content Type:Rapid Communication

     |  20 March 2018

   Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state

   Authors:Parmanand Malvi, Balkrishna Chaube, Shivendra Vikram Singh, Naoshad Mohammad, Maleppillil Vavachan Vijayakumar, Snahlata Singh, Surbhi Chouhan and Manoj Kumar Bhat
5. Content Type:Research

     |  8 March 2018

   Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA

   Authors:Natthakan Thongon, Chiara Zucal, Vito Giuseppe D’Agostino, Toma Tebaldi, Silvia Ravera, Federica Zamporlini, Francesco Piacente, Ruxanda Moschoi, Nadia Raffaelli, Alessandro Quattrone, Alessio Nencioni, Jean-Francois Peyron and Alessandro Provenzani

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