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Featured article: Fighting cancer with the immune system

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Studies have shown the immune system has the potential to remove tumor cells in a patient’s body. This article describes a method for generating antitumor  cytotoxic T lymphocytes (CTLs)  specific for the epitopes of the HER2/neu tumor-associated antigen. These CTLs are then shown to have a pronounced cytotoxic effect on tumor cells expressing the HER2/neu marker.

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1. Content Type:Research Article

     |  16 April 2018

   Therapeutic cancer vaccine: phase I clinical tolerance study of Hu-rhEGF-rP64k/Mont in patients with newly diagnosed advanced non-small cell lung cancer

   Authors:Puyuan Xing, Hongyu Wang, Sheng Yang, Xiaohong Han, Yan Sun and Yuankai Shi
2. Content Type:Research Article

     |  16 April 2018

   Neutrophils in primary gastric tumors are correlated with neutrophil infiltration in tumor-draining lymph nodes and the systemic inflammatory response

   Authors:Soichiro Hiramatsu, Hiroaki Tanaka, Junya Nishimura, Chie Sakimura, Tatsuro Tamura, Takahiro Toyokawa, Kazuya Muguruma, Masakazu Yashiro, Kosei Hirakawa and Masaichi Ohira
3. Content Type:Research Article

     |  21 March 2018

   Low HLA binding of diabetes-associated CD8+ T-cell epitopes is increased by post translational modifications

   Authors:John Sidney, Jose Luis Vela, Dave Friedrich, Ravi Kolla, Matthias von Herrath, Johnna D. Wesley and Alessandro Sette
4. Content Type:Review

     |  15 March 2018

   In silico prediction of cancer immunogens: current state of the art

   Authors:Irini A. Doytchinova and Darren R. Flower
5. Content Type:Research Article

     |  1 March 2018

   Utility of dominant epitopes derived from cell-wall protein LppZ for immunodiagnostic of pulmonary tuberculosis

   Authors:Jinjing Tan, Xiaoguang Wu, Suting Chen, Meng Gu, Hairong Huang and Wentao Yue

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