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Translational Neurodegeneration

Featured article: Current understanding of the molecular mechanisms in Parkinson's disease

This review provides basic conceptual information on the molecular mechanisms underlying Parkinson’s Disease, which may assist in the design of more effective drugs or other treatment strategies.

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1. CONTENT TYPE:REVIEW

     |  27 November 2017

   RNAi mechanisms in Huntington’s disease therapy: siRNA versus shRNA

   Authors:Sebastian Aguiar, Bram van der Gaag and Francesco Albert Bosco Cortese
2. CONTENT TYPE:RESEARCH

     |  24 November 2017

   Specific serum antibody binding to phosphorylated and non-phosphorylated tau in non-cognitively impaired, mildly cognitively impaired, and Alzheimer’s disease subjects: an exploratory study

   Authors:Andrea C. Klaver, Mary P. Coffey, David A. Bennett and David A. Loeffler
3. CONTENT TYPE:RESEARCH

     |  21 November 2017

   Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism

   Authors:Rafael Lazo-Gomez and Ricardo Tapia
4. CONTENT TYPE:RESEARCH

     |  30 October 2017

   Nicorandil potentiates sodium butyrate induced preconditioning of neurons and enhances their survival upon subsequent treatment with H2O2

   Authors:Parisa Tabeshmehr, Haider Kh Husnain, Mahin Salmannejad, Mahsa Sani, Seyed Mojtaba Hosseini and Mohammad Hossein Khorraminejad Shirazi
5. CONTENT TYPE:REVIEW

     |  25 October 2017

   Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

   Authors:Panchanan Maiti, Jayeeta Manna and Gary L. Dunbar

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