LYNCH SYNDROME AND PUBLIC HEALTH ► Public Health Genomics Knowledge Base (v1.0)

Public Health Genomics Knowledge Base (v1.0)

LYNCH SYNDROME AND PUBLIC HEALTH

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Last Updated: Feb 26, 2016

• Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort.
  Rosty Christophe, et al. BMJ open 2016 0 (2) e010293 (From HuGE Literature Finder)
• Finding the needle in a haystack: identification of cases of Lynch syndrome with MLH1 epimutation.
  Hitchins Megan P et al. Familial cancer 2016 Feb (From Genomics & Health Impact Scan Database)
• Kintalk Instructional Video
  Disease: Lynch syndrome|Breast Cancer|Ovarian Cancer; Type: Tools; State: Multiple States (FromImplementation Database)
• Kintalk
  Disease: Lynch syndrome|Breast Cancer|Ovarian Cancer; Type: Education|Tools; State: Multiple States (From Implementation Database)
• Update on Lynch syndrome genomics.
  Peltomäki Päivi et al. Familial cancer 2016 Feb (From Discoveries and Insights Database)
• Mismatch Repair Deficiency Testing in Clinical Practice.
  Hui Pei et al. Expert review of molecular diagnostics 2016 Feb (From Discoveries and Insights Database)
• Most patients at risk for Lynch syndrome not advised to undergo genetic testing, appropriate colonoscopy screening
  Patel SG et al, Am J Gastroenterology, February 17, 2016 (From Discoveries and Insights Database)
• Patients with colorectal cancer associated with Lynch syndrome and MLH1 promoter hypermethylation have similar prognoses.
  Haraldsdottir Sigurdis et al. Genetics in medicine : official journal of the American College of Medical Genetics 2016 Feb (From Genomics & Health Impact Scan Database)
• Lynch Syndrome Screening in the Gynecologic Tract: Current State of the Art.
  Mills Anne M et al. The American journal of surgical pathology 2016 Feb (From Genomics & Health Impact Scan Database)
• Patients with colorectal cancer associated with Lynch syndrome and MLH1 promoter hypermethylation have similar prognoses
  Sigurdis Haraldsdottir et al, Genetics in Medicine, February 11, 2016 (From Discoveries and Insights Database)
• AliveAndKickn, a hereditary cancer foundation, announces the launch of The HEROIC Registry for Lynch Syndrome genetic mutations, 
  PR Newswire, February 9, 2016 (From Genomics & Health Impact Scan Database)
• Knowledge and Uptake of Genetic Counseling and Colonoscopic Screening Among Individuals at Increased Risk for Lynch Syndrome and their Endoscopists from the Family Health Promotion Project.
  Patel Swati G et al. The American journal of gastroenterology 2016 Feb (From Genomics & Health Impact Scan Database)
• Targeted Screening With Combined Age- and Morphology-Based Criteria Enriches Detection of Lynch Syndrome in Endometrial Cancer.
  Lin Douglas I et al. International journal of surgical pathology 2016 Feb (From Genomics & Health Impact Scan Database)
• HSP110 T17 simplifies and improves the microsatellite instability testing in patients with colorectal cancer.
  Buhard Olivier, et al. Journal of medical genetics 2016 2 (From HuGE Literature Finder)
• Tools for Bidirectional Cancer Registry Reporting to Identify Individuals at Risk for Lynch syndrome
  Disease: Lynch syndrome; Type: Tools; State: Multiple States (From Implementation Database)
• Mismatch repair deficiency in Lynch syndrome-associated colorectal adenomas is more prevalent in older patients.
  Tanaka Masahiro et al. Histopathology 2016 Jan (From Genomics & Health Impact Scan Database)
• All Colon Colorectal Cancer Patients to be Screened for Lynch Syndrome, 
  Stop Colon Cancer Now, January 25, 2016 (From Genomics & Health Impact Scan Database)