Network Formed to Discover New Cancer OncoArraySusceptibility Variants

archive.constantcontact.com/fs170/1109148816547/archive/1115953717099.html

Network Formed to Discover New Cancer Susceptibility Variants

OncoArray Network Accepting New Members The OncoArray Network encompasses a group of disease-based consortia interested in gaining new insights into the genetic architecture and mechanisms underlying breast, ovarian, prostate, colorectal, and lung cancers.   To pursue this goal, they have partnered with Illumina in designing a new chip, the OncoArray, which includes approximately 570,000 single nucleotide polymorphism markers (SNPs); a backbone of approximately 260,000 SNPs providing genome-wide coverage of most common variants; fine-mapping markers for loci of interest identified for breast, ovarian, prostate, colorectal, lung, and other cancers; fine mapping of known susceptibility regions; and loci of interest to multiple cancer types (including loci associated with cancer- related phenotypes, drug metabolism, and radiation response).   Additionally, SNPs relating to quantitative phenotypes such as body mass index (BMI), height, and breast density that correlate with common cancer risks are also included. The OncoArray Network will process more than 400,000 samples of cancer cases and controls. Because of its high-density genotyping and fine mapping, this project offers an unprecedented opportunity to determine causal variants in known loci and to identify new and rarer variants. The OncoArray Network welcomes additional members, including investigators studying other diseases. Members can gain access to the SNP-limited annotation list and must agree to abide by the Network's internal data-sharing policies and publication guidelines.View the membership application form here. The OncoArray Network is funded in part by grants from the National Cancer Institute (NCI), Genome Canada, Cancer U.K., the European Union; and others. Features Network Formed to Discover New Cancer Susceptibility Variants   Two Biospecimen Resources are Now Accepting Proposals for Collaboration   The Breast Cancer and the Environment Research Program's 10th Anniversary and Annual Meeting    Meeting of NCI Cohort Consortium Members Focuses on Leveraging Existing Resources to Accelerate Discovery    Announcements  Funding Opportunity Announcements  Grants Policy Announcements  Job Opportunities  Upcoming Seminars & Workshops    Blog Post About Us  About EGRP Send Us Your Ideas  Contact Us  Funding Opportunity Announcements RFA-CA-13-015 Cancer Detection, Diagnosis, and Treatment Technologies for Global Health (UH2/UH3) Application due date: January 6, 2014 Expires: January 7, 2014 NCI Provocative Questions RFAs Application due dates: January 15, 2014; June 20, 2014 Expires: June 21, 2014 RFA-CA-13-010 Sub-Saharan African Collaborative HIV and Cancer Consortia (U54) Application due date:  January 17, 2014 Expires: January 18, 2014    RFA-HG-13-013 Interpreting Variation in Human Non-Coding Genomic Regions Using Computational Approaches and Experimental Assessment (R01) Application due dates: January 21, 2014; January 21, 2015 Expires: January 22, 2015 PAR-13-382 Analysis of Genome-Wide Gene-Environment (GxE) Interactions (R21) Application due date:  February 14, 2014 Expires: February 15, 2014 PA-14-003 Collaborative Activities to Promote Metabolomics Research (Admin. Supp.) Application due date: February 14, 2014 Expires: February 15, 2014 PAR-13-375 Nutrigenetics and Nutrigenomics Approaches for Nutrition Research (R01) Application due dates: March 20, 2014; March 19, 2015; March 22, 2016 Expires: March 23, 2016 PA-13-377 PA-13-378 Research on Malignancies in the Context of HIV/AIDS (R01, R21) Application due dates: Standard AIDS dates apply Expires: September 8, 2016  Grants Policy Announcements PAR-14-007 NCI Small Grants Program for Cancer Research (NCI Omnibus R03) was released November 21, 2013, Principal Investigators should note changes to application receipt dates. NOT-OD-14-028 Change in the NIH Continuous Submission Policy Job Opportunities Program Director, Clinical and Translational Epidemiology Branch, EGRP  Program Director, Host Susceptibility Factors Branch, EGRP Cancer Research Training Award Fellow, Associate Coordinator for Cancer Epidemiology Cohorts and Consortia, EGRP Chief, Laboratory of Translational Genomics, DCEG Upcoming Seminars & Workshops NCI-NIBIB Point of Care Technologies for Cancer Conference January 8-10, 2014 in Bethesda, MD 7th Biennial Cancer Survivorship Research Conference: Advancing Survivorship through Multilevel Collaborations Abstract Submission Deadline: January 22, 2014, 11:59 p.m. Evaluating Genomic Evidence for Medical Decision-Making: A Workshop February 3, 2014 in Washington, DC Complex Systems, Health Disparities & Population Health: Building Bridges February 24-25, 2014 in Bethesda, MD HIV Drug Resistance Program Conference: Host Factors and Cofactors in HIV Infection February 25, 2014 (rescheduled from October 16, 2013 due to government shutdown) in Frederick, MD Blog Post   The Continued Importance of Research in Gene-Environment Interactions in 21st Century Epidemiology About EGRP The Epidemiology and Genomics Research Program (EGRP), in theDivision of Cancer Control and Population Sciences (DCCPS)funds research in human populations to understand the causes of cancer and related outcomes. The Program fosters interdisciplinary collaborations, as well as the development and use of resources and technologies to advance cancer research and translation of this research, which serve as the basis for clinical and public health interventions.  Send Us Your Ideas EGRP encourages readers tosubmit items of interest to Cancer Epidemiology Matters E-News. EGRP reserves the right to decide whether or not materials are appropriate for inclusion.  Contact Us Epidemiology and Genomics Research Program Division of Cancer Control and Population Sciences National Cancer Institute 9609 Medical Center Drive 4 East, MSC 9763 Bethesda, MD  20892 (240) 276-6730 e-mail: nciepimatters@mail.nih.gov website: epi.grants.cancer.gov blog: blog-epi.grants.cancer.gov Twitter: twitter.com/NCIEpi For UPS, FedEx, and courier services, please use: Rockville, MD  20850