Fuchs endothelial dystrophy - Genetics Home Reference

Fuchs endothelial dystrophy - Genetics Home Reference: "Fuchs endothelial dystrophy

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* Description
* Genetic changes
* Inheritance
* Treatment
* Additional information
* Other names
* Glossary definitions

Reviewed June 2011


What is Fuchs endothelial dystrophy?

Fuchs endothelial dystrophy is a condition that causes vision problems. The first symptom of this condition is typically blurred vision in the morning that usually clears during the day. Over time, affected individuals lose the ability to see details (visual acuity). People with Fuchs endothelial dystrophy also become sensitive to bright lights.

Fuchs endothelial dystrophy specifically affects the front surface of the eye called the cornea. Deposits called guttae, which are detectable during an eye exam, form in the middle of the cornea and eventually spread. These guttae contribute to the loss of cells in the cornea, leading to vision problems. Tiny blisters may develop on the cornea, which can burst and cause eye pain.

The signs and symptoms of Fuchs endothelial dystrophy usually begin in a person's forties or fifties. A very rare early-onset variant of this condition starts to affect vision in a person's twenties.

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