CIENCIASMEDICASNEWS: febrero 2026

RARE DISEASE LEARNING CENTERS https://checkrare.com/rare-diseases-clinical-research-network/ Tenosynovial Giant Cell Tumor (TGCT) https://checkrare.com/tenosynovial-giant-cell-tumor-tgct/ Tenosynovial giant cell tumor (TGCT) is a non-malignant tumor involving the joint synovium, bursae, and tendon sheath. These rare tumors are sometimes referred to as giant cell tumor of the tendon sheath (GCT-TS) and/or pigmented villonodular synovitis (PVNS). Rett Syndrome https://checkrare.com/rett-syndrome/ Rett syndrome is a multisystem disorder that primarily affects girls; multiple loss-of-function mutations to the MECP2 gene are the cause of this rare disease. CME PROGRAMS Skeletal Involvement in Lysosomal Disorders https://checkrare.com/learning/p-skeletal-involvement-in-lysosomal-disorders/ Ozlem Goker-Alpan, MD, Founder and President, Lysosomal & Rare Disorders Research & Treatment Center (LDRTC) and Ravi Kamath, MD, PhD, of Fairfax Radiological Consultants & Inova Health System and University of Virginia School of Medicine Fairfax, Virginia, USA discuss best practices to identify and treat bone problems associated with lysosomal disorders. CREDITS: 1.0 CME | DURATION: 1.0 hours EXPIRES: 6/30/2026 | FEE: $0 Myasthenia Gravis Clinical Research Highlights: AAN 2025 https://checkrare.com/learning/p-myasthenia-gravis-clinical-research-highlights-aan-2025/ Dr. James Howard Jr, provides a summary of clinically relevant data presented at AAN 2025 that can enhance the care of patients with myasthenia gravis. CREDITS: 0.75 CME | DURATION: 45 minutes EXPIRES: 8/31/2026 | FEE: $0 Case Studies in Diagnosing and Managing FOP https://checkrare.com/learning/p-case-studies-in-diagnosing-and-managing-fop/ Christiaan Scott, MD, Professor of Pediatric Rheumatology at the University of Ottawa and Raphaella Stander, MBCHB, Pediatrician at Atlantic Children’s Practice, focused on three case studies to provide physicians with education on best practices to: 1) suspect and diagnose FOP, 2) monitor and manage younger children with FOP, and 3) monitor and manage older children and adults with FOP.

CLINICAL PERSPECTIVES Kygevvi for Patients With Thymidine Kinase 2 Deficiency https://checkrare.com/kygevvi-for-patients-with-thymidine-kinase-2-deficiency/ Kim Moran, Head of U.S. Rare Diseases at UCB, discusses the approval of Kygevvi (doxecitine and doxribtimine) for patients with thymidine kinase 2 deficiency (TK2d). The Use of Nipocalimab in Adolescent Patients With Generalized Myasthenia Gravis https://checkrare.com/the-use-of-nipocalimab-in-adolescent-patients-with-generalized-myasthenia-gravis/ Jonathan Strober, MD, pediatric neurologist and neuromuscular specialist at the University of California at San Francisco, discusses the use of nipocalimab in adolescent patients with generalized myasthenia gravis (gMG). EPIC Clinical Trial Design: Evaluating Nipocalimab Versus Efgartigimod in Patients With Myasthenia Gravis https://checkrare.com/epic-clinical-trial-design-evaluating-nipocalimab-versus-efgartigimod-in-patients-with-myasthenia-gravis/ Nolan Campbell, PhD, U.S. Medical Director at Johnson & Johnson, discusses the EPIC clinical trial design that will evaluate the efficacy of nipocalimab versus efgartigimod in patients with... Efficacy of Nipocalimab in Generalized and Ocular gMG: Long-Term Outcomes and Phase 3 VIVACITY-MG3 Findings https://checkrare.com/efficacy-of-nipocalimab-in-generalized-and-ocular-gmg-long-term-outcomes-and-phase-3-vivacity-mg3-findings/ Sindhu Ramchandren, MD, Executive Medical Director of Neuroscience at Johnson & Johnson, discusses long-term efficacy of nipocalimab in patients with generalized myasthenia gravis (gMG). ... The Shift to Precision Medicine in Myasthenia Gravis https://checkrare.com/the-shift-to-precision-medicine-in-myasthenia-gravis/ Alexandra C. Bayer Wildberger, PhD, Post-Doctoral Associate at Yale School of Medicine, discusses the shift to precision medicine in myasthenia gravis (MG).

CIENCIASMEDICASNEWS

domingo, 1 de febrero de 2026

The food nationalism of the new dietary guidelines The new food pyramid’s limited view of the ‘American’ diet dismisses the meals I grew up with

STAT readers on shared decision-making, prostate cancer screening, and more Keep those letters coming! By Torie BoschJan. 31, 2026 Editor, First Opinion

How Opvee, Indivior’s powerful overdose antidote, went bust Flop is unusual victory for harm reduction advocates, who cited expense and risk of withdrawal

RARE DISEASE LEARNING CENTERS +++++

Kygevvi for Patients With Thymidine Kinase 2 Deficiency by Madaline Spencer| +++++

RARE and undiagnosed

Pediatric Low-Grade Glioma With BRAF Alterations: Stories, Science, and Strategies Authors: Darren Hargrave, MBChB, MD; Cameron Miller; Enrico Opocher, MD; Sébastien Perreault, MD, FRCPC

Mastering Oral Therapies in CLL and MCL: Essential Strategies and Insights for Nurses Authors: Amy L. Goodrich, RN, MSN, CRNP-AC; Claudia Boglione, RN; Natacha Bolanos

Which metabolites most strongly predict type 2 diabetes risk beyond traditional factors (Medscape AI)

U.S. government has lost more than 10,000 STEM Ph.D.s since Trump took office A Science analysis reveals how many were fired, retired, or quit across 14 agencies

Viewpoint: Vaccine skeptics permeating the Trump administration are remaking U.S. health policy—for the worse Rachana Pradhan | January 28, 2026

Personalized health: When it comes to medicine, one size no longer fits all Richard Williams | January 29, 2026

Rejecting global science guidance, RFK, Jr.’s vaccine panel chair says polio shots should be optional Apoorva Mandavilli | New York Times | January 29, 2026

RFK, Jr.’s Children Health Defense files racketeering suit against American Academy of Pediatrics claiming it endorses vaccines because it’s on-the-take from drug makers Walker Bragman | Important Context | January 30, 2026

Optimizing Management of NF1-Associated Plexiform Neurofibromas: Expert Multidisciplinary Team Discussions Authors: Judith Eelloo, RGN, RSCN, MPhil; Darren Hargrave, MD; Zhichao Wang, MD, MPH; Kaleb Yohay, MD

Real-Time Insights Into the Diagnosis and Management of ATTR: From Genetic Insight to Therapeutic Innovation Authors: Kevin M. Alexander, MD; Marianna Fontana, MD, PhD; Ronald Witteles, MD

Addressing Challenges for Patients With HR+/HER2- EBC: Managing AEs and Optimizing Adherence Authors: Sarah Donahue, MPH, NP, AOCNP; Erika Hamilton, MD; Nadia Harbeck, MD, PhD

Patients Progressing on an AI ± CDK4/6 Inhibitors: From Biomarkers to Treatment Strategies Authors: Manali Bhave, MD; Nadia Harbeck, MD, PhD

Conference Insights: Breaking Developments in ALK-Positive NSCLC and ES-SCLC Authors: Solange Peters, MD, PhD; Shirish M. Gadgeel, MD; Rafal Dziadziuszko, MD, PhD

Which breast cancer subtype showed the best response to boost radiation in P-RAD (Medscape AI)