Can a Pen Catch Parkinson’s Before You Do? +++++++ +++

LATEST ON PARKINSON’S Can a Pen Catch Parkinson’s Before You Do? https://www.medscape.com/viewarticle/ai-pen-accurately-diagnoses-early-parkinsons-handwriting-2025a1000eyw?ecd=mkm_ret_250630_mscpmrk_neuro_Parkinsons_etid7533612&uac=148436CN&impID=7533612 Early Parkinson’s: New Drug Shows Promise https://www.medscape.com/viewarticle/novel-agent-shows-promise-early-parkinsons-disease-2025a10008yx?ecd=mkm_ret_250630_mscpmrk_neuro_Parkinsons_etid7533612&uac=148436CN&impID=7533612 Forget the Tremor: Parkinson’s First Signs https://www.medscape.com/viewarticle/forget-tremor-these-symptoms-come-first-parkinsons-2025a1000fj1?ecd=mkm_ret_250630_mscpmrk_neuro_Parkinsons_etid7533612&uac=148436CN&impID=7533612 Stem Cell Therapy for PD: ‘Significant First Step’ https://www.medscape.com/viewarticle/promising-new-data-stem-cell-therapy-parkinsons-2025a100094y?ecd=mkm_ret_250630_mscpmrk_neuro_Parkinsons_etid7533612&uac=148436CN&impID=7533612 Parkinson’s Risk Starts on Your Plate? https://www.medscape.com/viewarticle/ultraprocessed-foods-tied-early-signs-parkinsons-2025a1000b5p?ecd=mkm_ret_250630_mscpmrk_neuro_Parkinsons_etid7533612&uac=148436CN&impID=7533612 Golf Courses Linked to Higher PD Risk https://www.medscape.com/viewarticle/residential-proximity-golf-courses-linked-parkinsons-disease-2025a1000bau?ecd=mkm_ret_250630_mscpmrk_neuro_Parkinsons_etid7533612&uac=148436CN&impID=7533612 Want to Fight Parkinson’s? Grab a Leash https://www.medscape.com/viewarticle/simple-dog-walks-can-improve-life-patients-parkinsons-2025a10009qm?ecd=mkm_ret_250630_mscpmrk_neuro_Parkinsons_etid7533612&uac=148436CN&impID=7533612 MORE ON BRAIN HEALTH Do You Know Your Brain Care Score? https://www.medscape.com/viewarticle/do-you-know-your-brain-care-score-2025a1000fle?ecd=mkm_ret_250630_mscpmrk_neuro_Parkinsons_etid7533612&uac=148436CN&impID=7533612 Music Strikes a Chord for Brain Health https://www.medscape.com/viewarticle/music-strikes-chord-brain-health-2025a1000faa?ecd=mkm_ret_250630_mscpmrk_neuro_Parkinsons_etid7533612&uac=148436CN&impID=7533612 Thinking Cap to Measure Cognitive Load? https://www.medscape.com/viewarticle/scientists-invent-literal-thinking-cap-2025a1000dou?ecd=mkm_ret_250630_mscpmrk_neuro_Parkinsons_etid7533612&uac=148436CN&impID=7533612

FDA Drops REMS Programs for Some CAR-Ts M. Alexander Otto, PA, MMSc

https://www.medscape.com/viewarticle/fda-drops-rems-programs-some-car-ts-2025a1000hfn

ESMO Gynecological (ESMO Gyn) Cancers Congress 2025 + ++++++ +++

https://www.medscape.com/viewcollection/37812 Best of Oncology for 2025 So Far Most Popular News • Can This Diet Cut The Risk of Obesity-Related Cancers? https://www.medscape.com/viewarticle/mediterranean-diet-may-cut-risk-obesity-related-cancers-2025a10004vu?ecd=wnl_bestof_onc_250630_MSCPEDIT_etid7533016&uac=148436CN&impID=7533016 • The Cancer Risk Hiding in Your Patient’s Glass https://www.medscape.com/viewarticle/cancer-risk-hiding-your-patients-glass-rethinking-alcohol-2025a1000c9d?ecd=wnl_bestof_onc_250630_MSCPEDIT_etid7533016&uac=148436CN&impID=7533016 • Can a Breath Test Ferret Out Lung Cancer? https://www.medscape.com/viewarticle/can-breath-test-ferret-out-lung-cancer-2025a10008oz?ecd=wnl_bestof_onc_250630_MSCPEDIT_etid7533016&uac=148436CN&impID=7533016 • As CT Use Rises, So Does Projected Risk for Future Cancers https://www.medscape.com/viewarticle/ct-use-rises-so-does-projected-risk-future-cancers-2025a10008ub?ecd=wnl_bestof_onc_250630_MSCPEDIT_etid7533016&uac=148436CN&impID=7533016 • How Stress Shapes Cancer’s Course https://www.medscape.com/s/viewarticle/how-stress-shapes-cancers-course-2025a10008zq?ecd=wnl_bestof_onc_250630_MSCPEDIT_etid7533016&uac=148436CN&impID=7533016 • Olive Oil May Cut the Risk for Specific Breast Cancer Types https://www.medscape.com/viewarticle/olive-oil-may-cut-risk-specific-breast-cancer-types-2025a1000e33?ecd=wnl_bestof_onc_250630_MSCPEDIT_etid7533016&uac=148436CN&impID=7533016 Top Clinical Guidelines • Top Tips: Metastatic Breast Cancer https://www.medscape.co.uk/viewarticle/top-tips-metastatic-breast-cancer-2025a1000dc0?ecd=wnl_bestof_onc_250630_MSCPEDIT_etid7533016&uac=148436CN&impID=7533016&sso=true • ESMO Recommendations on Bladder Cancer https://www.medscape.co.uk/viewarticle/guideline-essentials-2021-esmo-recommendations-bladder-2024a10003qf?ecd=wnl_bestof_onc_250630_MSCPEDIT_etid7533016&uac=148436CN&impID=7533016&sso=true • Pancreatic Cancer: Clinical Trials Drive Therapy Towards Precision Medicine https://www.medscape.co.uk/viewarticle/pancreatic-cancer-clinical-trials-drive-therapy-towards-2025a10000zk?ecd=wnl_bestof_onc_250630_MSCPEDIT_etid7533016&uac=148436CN&impID=7533016&sso=true

The Journal of Headache and Pain

https://thejournalofheadacheandpain.biomedcentral.com/

BMC Sports Science, Medicine and Rehabilitation

https://bmcsportsscimedrehabil.biomedcentral.com/

Mobile Health (mHealth) Technology for Eating-Related Behaviour and Health Problems Related to Obesity in Japan: a Systematic Review

https://bpsmedicine.biomedcentral.com/

Addiction Science & Clinical Practice

https://ascpjournal.biomedcentral.com/

BMC Artificial Intelligence

https://bmcartificialintel.biomedcentral.com/

Journal of Neuroinflammation

https://jneuroinflammation.biomedcentral.com/

Perivascular interactions and tissue properties modulate directional glymphatic transport in the brain

https://fluidsbarrierscns.biomedcentral.com/

BMC Neuroscience

https://bmcneurosci.biomedcentral.com/

The economic burden of subjective cognitive decline, mild cognitive impairment and Alzheimer's dementia: excess costs and associated clinical and risk factors

https://alzres.biomedcentral.com/

FTO (fat-mass and obesity-associated protein) deficiency aggravates age-dependent depression-like behaviors and cognitive impairment

https://behavioralandbrainfunctions.biomedcentral.com/

Acta Neuropathologica Communications

https://actaneurocomms.biomedcentral.com/

Nearly 9 million asthma exacerbations among adults each year in the U.S., it’s time to change to an anti-inflammatory rescue approach

https://www.statnews.com/sponsor/2025/06/16/nearly-9-million-asthma-exacerbations-among-adults-each-year-in-the-us-its-time-to-change-to-an-anti-inflammatory-rescue-approach/

Understanding the interconnected roles of microbial, metabolic, and immune biomarkers in IBD

https://www.news-medical.net/news/20250619/Understanding-the-interconnected-roles-of-microbial-metabolic-and-immune-biomarkers-in-IBD.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=metabolomics_newsletter_26_june_2025

Ultra-processed foods increase risk of anxiety and depression, study shows

https://www.news-medical.net/news/20250505/Ultra-processed-foods-increase-risk-of-anxiety-and-depression-study-shows.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=metabolomics_newsletter_26_june_2025

Jun 27, 2025 This Week in Cardiology Podcast John M. Mandrola, MD June 27, 2025

https://www.medscape.com/viewarticle/1002667?ecd=wnl_edit_tpal_etid7530898&uac=148436CN&impID=7530898

Antiretroviral therapy and obesity risk: a weighty question Jennifer Manne-Goehler,Nomathemba Chandiwana

https://www.thelancet.com/issue/S2352-3018(25)X0007-2

Honouring the amyotrophic lateral sclerosis research pledge The Lancet Neurology

https://www.thelancet.com/issue/S1474-4422(25)X0007-7

Alcohol and health: time for Europe to sober up The Lancet Gastroenterology & Hepatology

https://www.thelancet.com/issue/S2468-1253(25)X0006-6

Advances and challenges in childhood pneumonia The Lancet Child & Adolescent Health

https://www.thelancet.com/journals/lanchi/issue/vol9no7/PIIS2352-4642(25)X0007-9

Psychiatry: Incidence, co-occurring psychiatric conditions, and sex differences in young people without intellectual impairment who are autistic, ADHD, or autistic–ADHD: a population-based cross-sectional study in Iceland

https://www.thelancet.com/collections/psychiatry?dgcid=hubspot_email_infocusalerts-psychiatry_feature&parent=001633&startPage=&ContentItemType=fla&utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz-_tR1ZRZwyNzHq8dg-NSZtwEQGdz7Y81g2ttPybpNNd4AcyI78Tr1YrwmnOVSNlynHHSEbc0caVH4H91nGXCDu832LLvg&_hsmi=368979093&utm_content=367566809&utm_source=hs_email

European Alliance of Associations for Rheumatology 2025 Annual Meeting June 11 - 14, 2025 | Barcelona, Spain +...

https://www.medscape.com/viewcollection/37791?ecd=WNL_conf_rheum_EULAR-SPON_250628_MSCPEDIT_etid7529158&uac=148436CN&impID=7529158

Benign Prostatic Hyperplasia: Evaluation and Treatment Josh Palka, DO |

https://reference.medscape.com/slideshow/prostatic-hyperplasia-6013093

Burning Up? A Guide To Recognizing And Managing Heat Illness Zina Semenovskaya, MD, FAWM; Sage Wiener, MD | June 20, 2025 |

https://reference.medscape.com/slideshow/heat-illness-6004448

Understanding Growth Disorders: 7 Cases Qurrat-ul-Ann Saqib, MBBS, FCPS Pediatrics; Sumaira Nabi, MBBS, FCPS Neurology

https://reference.medscape.com/slideshow/growth-disorders-6009618

Metastatic Breast Cancer: Current and Emerging Treatments Shimoli Barot, MD | June 20, 2025 |

https://reference.medscape.com/slideshow/mbc-6018138?ecd=wnl_critimg_250627_mscpref_etid7519620

New MASLD Guidelines | ‘Silent Killer’ Can Be Cured ++++++ +++ ++++

MASLD & MASH NEWS New MASLD Guidelines Issued https://www.medscape.com/viewarticle/ada-issues-new-masld-guidelines-2025a1000esb?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 How GLP-1s May Reverse MASH https://www.medscape.com/viewarticle/glp-1s-treat-and-even-reverse-some-forms-liver-disease-2025a1000e51?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 Promising Diet Option in MASLD https://www.medscape.com/viewarticle/time-restricted-mediterranean-diet-shows-promise-masld-2025a1000686?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 SGLT2i Helps Treat Progressive Liver Disease https://www.medscape.com/viewarticle/popular-diabetes-drug-helps-treat-progressive-liver-disease-2025a1000fqr?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 Predict MASLD 16 Years in Advance https://www.medscape.com/viewarticle/key-blood-proteins-predict-masld-16-years-advance-2025a1000a1a?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 Novel Genetic Variant May Drive MASLD https://www.medscape.com/viewarticle/novel-genetic-variant-may-drive-masld-2025a1000cin?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 HEPATITIS UPDATES The ‘Silent Killer’ That Can Be Cured https://www.medscape.com/viewarticle/clinicians-can-prescribe-cure-hepatitis-c-most-kids-never-2025a1000a42?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 Universal Screening for Hep B https://www.medscape.com/viewarticle/dont-forget-these-infectious-risk-based-disease-screenings-2025a1000f2o?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 ‘Missed Opportunities’ in Liver Disease Diagnoses https://www.medscape.com/viewarticle/most-chronic-hepatitis-b-diagnoses-us-are-late-2025a1000fv9?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 ALSO OF INTEREST Metabolic Alcoholic Liver Disease: 5 Things to Know https://www.medscape.com/viewarticle/metabolic-alcoholic-liver-disease-5-things-know-2025a1000a7e?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 AHA Backtracks on Alcohol’s Heart Benefits https://www.medscape.com/viewarticle/new-aha-scientific-statement-reconsiders-moderate-alcohol-2025a1000g00?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 Sobering Figures: Alcohol’s Link to GI Cancer https://www.medscape.com/viewarticle/sobering-figures-alcohols-link-gi-cancer-2025a1000f0r?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194 Alcoholic Hepatitis With AKI: Does Pentoxifylline Work? https://www.medscape.com/viewarticle/pentoxifylline-ineffective-alcoholic-hepatitis-aki-2025a1000csj?ecd=mkm_ret_250628_mscpmrk_gastro_liver-diseases_etid7529194&uac=148436CN&impID=7529194

Neurology: Diagnostic and prognostic value of α-synuclein seed amplification assay kinetic measures in Parkinson's disease: a longitudinal cohort study +...

https://www.thelancet.com/collections/neurology?dgcid=hubspot_email_infocusalerts-neurology_feature&parent=001585&startPage=&ContentItemType=fla&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-_9w9yZ69o1GnrhAhtr7kiW5wUjV6pK7FfmBj0oJ3V_w2hX4t3qTjjVYwuwdtDbCj2KsHIwHaPfdSK543IPntguxhCyIw&_hsmi=368876190&utm_content=367567103&utm_source=hs_email

Clinical Trials in CLL and MCL: Expert In-Depth Analysis Authors: Chan Cheah, MBBS, DMSc; Nirav N. Shah, MD; Jennifer A. Woyach, MD

https://www.medscape.org/viewarticle/1002400?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250627-OUS-HONC-1002400-cta

Patient-Centered Paroxysmal Nocturnal Hemoglobinuria Treatment and the Role of Terminal Complement Inhibitors Authors: Regis Peffault de Latour, MD, PhD; Talha Munir, MBChB, PhD; Rachel Paine; Richard Kelly, MBChB, PhD; Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath

https://www.medscape.org/viewarticle/1002332?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250627-OUS-HONC-1002332-cta

18th International Conference on Malignant Lymphoma (ICML) 2025

https://www.medscape.com/viewcollection/37821

IMPACT CLL & MCL: IMPlementing Advances in Cancer Treatment for Chronic Lymphocytic Leukemia and Mantle Cell Lymphoma

https://www.medscape.org/advances/impact-cll-mcl-2025a1000ar6

Immunotherapy - A Revolutionary Approach for Difficult-to-Treat Cancers: Comprehensive Learning Center

https://www.medscape.org/sites/advances/cancer-immunotherapy

Oncology: Focus on the Changing Therapeutic Landscape

https://www.medscape.org/sites/advances/novel-treatments-oncology

Navigating PD-L1 Testing and Patient-Centered Treatment of Gastroesophageal Cancer: A Guide for All Oncology Settings Authors: Elizabeth Smyth, MD; David Chuter; Manish Shah, MD, FASCO

https://www.medscape.org/viewarticle/1002597

Advancing Patient-Centered Care in mCRPC: Exploring PARP Inhibitor Combinations Authors: Neeraj Agarwal, MD, FASCO; Karim Fizazi, MD, PhD

https://www.medscape.org/viewarticle/1002353?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250628-OUS-HONC-1002353-cta

Most Read Papers - Cancer Science & Oncogenesis

https://read.qxmd.com/collection/1133?ecd=wnl_readmost_250627

ASK TO ADVANCE: TOUGH QUESTIONS TO ASK YOUR BOSS

Ask To Advance: Tough Questions to Ask Your Boss By Ivanhoe Broadcast News on July 4, 2025 https://www.ivanhoe.com/?p=35666&preview=1&_ppp=bc6486188d

SKILLS THAT PAY: WHAT HIRING MANAGERS ARE LOOKING FOR

Skills That Pay: What Hiring Managers Are Looking For By Ivanhoe Broadcast News on July 3, 2025 https://www.ivanhoe.com/?p=35663&preview=1&_ppp=ed8bcd888f

POWER INTERVIEWING: STRATEGIES FOR NEURODIVERGENT JOB SUCCESS

Power Interviewing: Strategies For Neurodivergent Job Success By Ivanhoe Broadcast News on July 2, 2025 https://www.ivanhoe.com/?p=35660&preview=1&_ppp=8639138942

CELEBRATING THE 4TH: REDEFINING PATRIOTISM

Celebrating The 4th: Redefining Patriotism By Ivanhoe Broadcast News on July 1, 2025 https://www.ivanhoe.com/?p=35657&preview=1&_ppp=d79be567e8

MAKING MONEY BUT STILL STRESSED: ARE YOU A HENRY?

Making Money But Still Stressed: Are You A HENRY? By Ivanhoe Broadcast News on June 30, 2025 https://www.ivanhoe.com/?p=35647&preview=1&_ppp=09c0c32f0f

Elaborate Skin Care Routines Can Cause Teens More Harm Than Good Kaitlin Sullivan June 27, 2025

https://www.medscape.com/viewarticle/elaborate-skin-care-routines-can-cause-teens-more-harm-than-2025a1000ha5

Fast Five Quiz: Sexual Interest Disorders Stephen Soreff, MD | June 25, 2025

https://reference.medscape.com/viewarticle/fast-five-quiz-sexual-interest-disorders-2025a1000ebw?_gl=1*t4v7fi*_gcl_au*MTczMzE3MjAxOS4xNzQ2NzI0NDU0

Without Measles Herd Immunity, Vulnerable Kids Are at Risk Paul A. Offit, MD; Margot L. Savoy, MD; Robert M. Jacobson, MD Medscape | June 27, 2025

https://www.medscape.com/viewarticle/without-measles-herd-immunity-vulnerable-kids-are-risk-2025a1000fpi

Transabdominal Ultrasound May Help Monitor Cystic Pancreatic Lesions Edited by Mandeep Singh Rawat Medscape UK June 27, 2025

https://www.medscape.com/viewarticle/transabdominal-ultrasound-may-help-monitor-cystic-pancreatic-2025a1000h1z

MRI Reveals Joint Damage After Cancer Treatment Edited by Anushree Chaphalkar Medscape UK June 27, 2025

https://www.medscape.com/viewarticle/mri-reveals-joint-damage-after-cancer-treatment-2025a1000h12

Pollution and Extreme Weather Tied to Higher Atopic Dermatitis Burden in Adults Edited by Deepa Varma June 27, 2025

https://www.medscape.com/viewarticle/pollution-and-extreme-weather-tied-higher-atopic-dermatitis-2025a1000hak

A Simple Way to Close Racial Gaps in Cancer Trial Enrollment Edited by Gargi Mukherjee June 27, 2025

https://www.medscape.com/viewarticle/simple-way-close-racial-gaps-cancer-trial-enrollment-2025a1000han

Unexplained Death? New French Guidelines Say Investigate Interviewer: Christophe Gattuso; Interviewee: Emmanuel Margueritte, MD | June 27, 2025

https://www.medscape.com/viewarticle/sudden-death-new-french-guidelines-say-investigate-2025a1000ha8

Body Fat Beats BMI in Predicting Death Lisa M. Basile June 26, 2025

https://www.medscape.com/viewarticle/body-fat-beats-bmi-predicting-death-2025a1000h4h

Biomaterials for better diabetes cell therapy Aiming to restore insulin function in type 1 diabetes, Lonnie Shea develops scaffolds that support the growth and transplantation of pancreatic islet structures.

https://www.drugdiscoverynews.com/biomaterials-for-better-diabetes-cell-therapy-15745?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-9JgnAVBqakHaNaOa1uL65iBW4xXP_i9UV1XOLgvW9h6u-IBUI1d4yK0KZZmx6TE5eAE1YOWfHwe5UqnK9Q2F6YKaHYGw&_hsmi=368832341&utm_content=368832341&utm_source=hs_email

Can a probiotic prevent type 1 diabetes in children? An upcoming clinical study will test whether a B. infantis probiotic can prevent the development of type 1 diabetes in predisposed infants.

https://www.drugdiscoverynews.com/can-a-probiotic-prevent-type-1-diabetes-in-children-15191?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-8HacAagb4Ryj_4lwRJXgIng6Md7GS3JA0Qt4Ek-S-JDXsXNBTJhWN39i6PJrzWsC_VaxFXcqNWzbVJY0DA1g4U3YsETQ&_hsmi=368832341&utm_content=368832341&utm_source=hs_email

Weekly Rundown: New therapy offers hope for type 1 diabetes Two new FDA approvals and promising clinical trial results for drugs to treat diabetes and lung cancer, and more led the news this week.

https://www.drugdiscoverynews.com/weekly-rundown-new-therapy-offers-hope-for-type-1-diabetes-16476?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-9qYEZib0dHfv80CjtfcJwjiQMLftOjvPvAOyEMNlfL36nnIWfVkdcVym9yIUaPy20t8IIJ_gW0iEDsr5IJG5SJrvg1AA&_hsmi=368832341&utm_content=368832341&utm_source=hs_email

GLP-1 and amylin receptor multiagonism with amycretin for obesity management

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01250-4/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_ada25&_hsenc=p2ANqtz--ZeolYJodGI-40dBYkcXnozq17VZBFMcL7wnZDRs9m999tIRh3kjZt5MZFBcPqwgTKUz6Gz8qY0-xrjqBh2AmQF87xHA&_hsmi=368028124&utm_content=368028124&utm_source=hs_email

Future of once-weekly insulins in type 2 diabetes: efficacy and safety

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01098-0/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_ada25&_hsenc=p2ANqtz-_lF5Hr9DZu4coH0meF8o4zkexOuh3tQAYTWEfzSm5k81Pnjsd93taASva9GUhiX4WbpCffKjfDYjkIiHXnZUNFPfyosQ&_hsmi=368028124&utm_content=368028124&utm_source=hs_email

Amycretin, a novel, unimolecular GLP-1 and amylin receptor agonist administered subcutaneously: results from a phase 1b/2a randomised controlled study

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01185-7/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_ada25&_hsenc=p2ANqtz--DkNXxTxDigBu9BBuc3-HC9wDwD8GkNRoKsP41PBLAoTkbLF8xbT6v1pBdHxz5WW6S4-6NKGdRQReuZ5zkog0_MTJKMA&_hsmi=368028124&utm_content=368028124&utm_source=hs_email

Safety, tolerability, pharmacokinetics, and pharmacodynamics of the first-in-class GLP-1 and amylin receptor agonist, amycretin: a first-in-human, phase 1, double-blind, randomised, placebo-controlled trial

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01176-6/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_ada25&_hsenc=p2ANqtz-8P427_35XSbnPnRxF0JXjd0X26q3W_QG9BAqpM_XUPQUp7yvJxD0NLkkFFdnkgBmqg2CFxJfRy8UsVJP9cZ_XgMZFaVQ&_hsmi=368028124&utm_content=368028124&utm_source=hs_email

Once-weekly insulin efsitora alfa versus once-daily insulin glargine U100 in adults with type 2 diabetes treated with basal and prandial insulin (QWINT-4): a phase 3, randomised, non-inferiority trial

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01069-4/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_ada25&_hsenc=p2ANqtz-_EG_gJBH57SdJpUcmJTyGAMIIR0DJxJlDSdRNtjMo5ON1Dm4l7xRtUUQq8ywVJfRNRfgW8U4SiR1YyU3gL8KWtAhXxEw&_hsmi=368028124&utm_content=368028124&utm_source=hs_email

Once-weekly insulin efsitora alfa versus once-daily insulin degludec in adults with type 2 diabetes currently treated with basal insulin (QWINT-3): a phase 3, randomised, non-inferiority trial

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01044-X/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_ada25&_hsenc=p2ANqtz-_LDS3egIvt3Yu3NsezjKslWC2IJqxY0iBFCTWlLHhYpeaiRNW2xVSs_-nzWabULh77g2HnVRfcofllJRZxlvjtOpsBkA&_hsmi=368028124&utm_content=368028124&utm_source=hs_email

AMD | Ticks | Parents’ Substance Abuse | Headaches | Heat & Alcohol

https://content.govdelivery.com/accounts/USNIH/bulletins/3e55f2e?reqfrom=share

Early-onset type 2 diabetes: no time for defeatism

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01295-4/fulltext?dgcid=raven_jbs_etoc_email Future of once-weekly insulins in type 2 diabetes: efficacy and safety https://www.thelancet.com/journals/lancet/issue/vol405no10497/PIIS0140-6736(25)X0026-X

It’s Complicated: Navigating Neoadjuvant Therapy for Lung Cancer Surgical Candidates Mark G. Kris, MD | June 26, 2025

https://www.medscape.com/viewarticle/its-complicated-navigating-neoadjuvant-therapy-lung-cancer-2025a1000fu6

Q&A: Familial and Genetic Risk in Ovarian Cancer Maurie Markman, MD | June 26, 2025

https://www.medscape.com/viewarticle/q-familial-and-genetic-risk-ovarian-cancer-2025a1000gko

AI-Derived Risk Score May Improve Risk Stratification of Squamous Cell Carcinomas John Jesitus June 26, 2025

https://www.medscape.com/viewarticle/ai-derived-risk-score-may-improve-risk-stratification-2025a1000h5z

Routine Checks for Cancer Metastases: A Help or Harm? Megan Brooks

https://www.medscape.com/viewarticle/routine-checks-cancer-metastases-help-or-harm-2025a1000h03

The Rise of Protein Degraders for Hematologic Malignancies: Exploring the Latest Data From ASH 2024 Authors: Sagar Lonial, MD, FACP; Constatine Tam, MBBS, MD, FRACP, FRCPath; Julio Chavez, MD, MS

https://www.medscape.org/viewarticle/1002295?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250626-OUS-HONC-1002295-cta

Nanny state hypocrisy: When Michelle Obama advocated improving American’s diet, she was mocked. Now it’s mainstream MAHA Marcia Brown | Politico | June 26, 2025

https://geneticliteracyproject.org/2025/06/26/nanny-state-hypocrisy-when-michelle-obama-advocated-improving-americans-diet-she-was-mocked-now-its-mainstream-maha/?mc_cid=d5b0b997dd&mc_eid=b73600b7ac

Food and farming industry pushes back against RFK, Jr.’s MAHA-targeting of agricultural chemicals Annie Gasparro, Jacob Bunge | Wall Street Journal | June 26, 2025

https://geneticliteracyproject.org/2025/06/26/food-and-farming-industry-pushes-back-against-rfk-jr-s-maha-targeting-of-agricultural-chemicals/?mc_cid=d5b0b997dd&mc_eid=b73600b7ac

Who’s my daddy? Offspring of two male mice father a child Jonathan Chadwick | Daily Mail (UK) | June 26, 2025

https://geneticliteracyproject.org/2025/06/26/whos-my-daddy-offspring-of-two-male-mice-father-a-child/?mc_cid=d5b0b997dd&mc_eid=b73600b7ac

How testosterone and estrogen have driven human evolution Eric Ralls | Earth.com | June 26, 2025

https://geneticliteracyproject.org/2025/06/26/how-testosterone-and-estrogen-have-driven-human-evolution/?mc_cid=d5b0b997dd&mc_eid=b73600b7ac

Synthetic, genetically engineered, and ‘Made in China’: Busting supplement industry myths about the natural wonders of Vitamin C Josh Bloom | June 26, 2025

https://geneticliteracyproject.org/2025/06/26/synthetic-genetically-engineered-and-made-in-china-busting-supplement-industry-myths-about-the-natural-wonders-of-vitamin-a/?mc_cid=d5b0b997dd&mc_eid=b73600b7ac

Loneliness Not Tied to Mortality in Older Adult Home Care Fran Lowry June 26, 2025

https://www.medscape.com/viewarticle/loneliness-not-tied-mortality-older-adult-home-care-2025a1000h4k?ecd=wnl_edit_tpal_etid7526564&uac=148436CN&impID=7526564

Inflammatory cells may persist despite biologic therapy in severe asthma

https://www.news-medical.net/news/20250626/Inflammatory-cells-may-persist-despite-biologic-therapy-in-severe-asthma.aspx

Sleep patterns change with geography, seasons, and daily schedules ++

https://www.news-medical.net/news/20250626/Sleep-patterns-change-with-geography-seasons-and-daily-schedules.aspx Sleep deficiency worsens pain mechanisms in migraine sufferers https://www.news-medical.net/news/20250626/Sleep-deficiency-worsens-pain-mechanisms-in-migraine-sufferers.aspx

Meningiomas more common in older women than previously known

https://www.news-medical.net/news/20250626/Meningiomas-more-common-in-older-women-than-previously-known.aspx

Living with Friedreich’s Ataxia: My experience with mobility and communication barriers June 2025

https://www.eurordis.org/living-with-friedreichs-ataxia/

Housing is Health Care The Lancet Respiratory Medicine

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00207-3/fulltext?dgcid=raven_jbs_etoc_email Preoxygenation for tracheal intubation in adults who are critically ill: time to abandon the facemask? https://www.thelancet.com/journals/lanres/issue/vol13no7/PIIS2213-2600(25)X0007-2

COVID-19 Antivirals: Real-World Evidence Review Authors: Robert L. Gottlieb, MD, PhD, FACC, FAST, FIDSA; Luke S.P. Moore, FRCPath, FRCP, PhD, MPH, MSc, DTM&H, DipULT, FHEA, MBChB

https://www.medscape.org/viewarticle/1002326?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250625-OUS-HONC-1002326-cta

Semaglutide for clozapine-treated patients with schizophrenia Sri Mahavir Agarwal,Margaret Hahn

Semaglutide for clozapine-treated patients with schizophrenia Sri Mahavir Agarwal,Margaret Hahn https://www.thelancet.com/journals/lanpsy/issue/vol12no7/PIIS2215-0366(25)X0007-9

Progress in elimination of vertical HIV transmission

https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00167-5/fulltext?dgcid=raven_jbs_etoc_email Antiretroviral therapy and obesity risk: a weighty question https://www.thelancet.com/journals/lanhiv/issue/vol12no7/PIIS2352-3018(25)X0007-2

Protecting transgender and gender-diverse health

https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(25)00233-5/fulltext?dgcid=raven_jbs_etoc_email Killed whole-cell cholera vaccines: is the evidence sufficient for their widespread use? https://www.thelancet.com/journals/langlo/issue/vol13no7/PIIS2214-109X(25)X0007-3

New insights into the role of diet and microbiome in gastric cancer

https://www.news-medical.net/news/20250625/New-insights-into-the-role-of-diet-and-microbiome-in-gastric-cancer.aspx

New guidance helps GPs manage patients using weight loss drugs

https://www.news-medical.net/news/20250625/New-guidance-helps-GPs-manage-patients-using-weight-loss-drugs.aspx

New study reveals health risks from metals in popular disposable e-cigarettes

https://www.news-medical.net/news/20250625/New-study-reveals-health-risks-from-metals-in-popular-disposable-e-cigarettes.aspx

Under the Skin: Revolutionizing Immunotherapy Delivery in Lung Cancer Authors: Sanjay Popat, PhD, FRCP; Alba Silverio Pons, RN; Alba Manzaneque, BCOP; Debra Montague

https://www.medscape.org/viewarticle/1002630

Triple-Negative Breast Lesions Turn Out to Be Myeloma Wolfgang Paik Medscape UK June 25, 2025

https://www.medscape.com/viewarticle/triple-negative-breast-lesions-turn-out-be-myeloma-2025a1000h02

Analyzing the Sacred Moments That Heal the Healers Mia Sims June 25, 2025

https://www.medscape.com/viewarticle/analyzing-sacred-moments-heal-healers-2025a1000h11

US Stillbirth: A Preventable Tragedy That Demands Clinical Leadership Samantha Durante Banerjee, BS-Economics, BAS | June 25, 2025

https://www.medscape.com/viewarticle/us-stillbirth-preventable-tragedy-demands-clinical-2025a1000g3u

Two 'Spectacular' Studies and Other Movement Disorder Updates Hans Christoph Diener, MD, PhD | June 25, 2025

https://www.medscape.com/viewarticle/two-spectacular-studies-and-other-movement-disorder-updates-2025a1000gjy

A Lesson in Humility: Reviewing Medical 'Truths' Neil Skolnik, MD | June 25, 2025

https://www.medscape.com/viewarticle/lesson-humility-reviewing-medical-truths-2025a1000gp8

Many Paths, One Purpose: Cancer Survivorship Across Cultures Medscape TV Program

https://www.medscape.com/mtv/cancer-survivorship-s03/e01

Mindfulness and Tai Chi Improve Mood in Cancer Survivors Edited by Gargi Mukherjee June 25, 2025

https://www.medscape.com/viewarticle/mindfulness-and-tai-chi-improve-mood-cancer-survivors-2025a1000h1s

Stewardship Cuts IV Treatment for Paediatric Bone Infections Edited by Satish Kumar M Medscape UK June 25, 2025

https://www.medscape.com/viewarticle/stewardship-cuts-iv-treatment-paediatric-bone-infections-2025a1000gnh

Epilepsy Medications Drive Adverse Pregnancy Outcomes Edited by Satish Kumar M Medscape UK June 25, 2025

https://www.medscape.com/viewarticle/epilepsy-medications-drive-adverse-pregnancy-outcomes-2025a1000gn9

Shifting the Narrative in Women’s Health Manuela Callari June 25, 2025

https://www.medscape.com/viewarticle/shifting-narrative-womens-health-2025a1000h1g

Guselkumab Benefits Patients With Skin of Color, Psoriasis Edited by Deepa Varma June 25, 2025

https://www.medscape.com/viewarticle/guselkumab-benefits-patients-skin-color-psoriasis-2025a1000h1r

Could Traveling by Bicycle Protect Against Dementia? Edited by Sneha Gupta June 24, 2025

https://www.medscape.com/viewarticle/could-traveling-bicycle-protect-against-dementia-2025a1000gzr

Viewpoint: RFK, Jr. wrongly demonizes the safe and effective HPV vaccine Gardasil Chuck Dinerstein | June 25, 2025

https://geneticliteracyproject.org/2025/06/25/viewpoint-rfk-jr-wrongly-demonizes-the-safe-and-effective-hpv-vaccine-gardasil/?mc_cid=1d9e8b93a7&mc_eid=b73600b7ac

Precise Measurements Can Help Cancer Patients Live Longer, Healthier Lives June 25, 2025 By: Stephen Russek

https://www.nist.gov/blogs/taking-measure/precise-measurements-can-help-cancer-patients-live-longer-healthier-lives

Clinic 1: Exploring CSF Biomarker Testing in AD: Use, Interpretation, and Patient-Related Communication Authors: Michael H. Rosenbloom, MD, FAAN

https://www.medscape.org/viewarticle/1002542_sidebar9?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_250625-1002542-en-lang-neur

Novel combination therapy targets m6A pathway to combat joint erosion in rheumatoid arthritis

https://www.news-medical.net/news/20250624/Novel-combination-therapy-targets-m6A-pathway-to-combat-joint-erosion-in-rheumatoid-arthritis.aspx

How Millennials and Gen Z Are Driving Evidence-Based Wellness Trends +++

https://www.news-medical.net/health/How-Millennials-and-Gen-Z-Are-Driving-Evidence-Based-Wellness-Trends.aspx How Do I Know if Social Media Is Affecting My Mental Health? https://www.news-medical.net/health/How-Do-I-Know-if-Social-Media-Is-Affecting-My-Mental-Health.aspx Tackling the Dual Epidemics of HIV and Addiction https://www.news-medical.net/health/Tackling-the-Dual-Epidemics-of-HIV-and-Addiction.aspx

Scientists warn of rising threat as poultry disease shows signs of jumping to humans

https://www.news-medical.net/news/20250623/Scientists-warn-of-rising-threat-as-poultry-disease-shows-signs-of-jumping-to-humans.aspx

Uncovering the Impact of Hepatitis B on HIV Treatment Authors: Chloe Orkin, MD

https://www.medscape.org/viewarticle/1002548_sidebar9

Collaborative Management of EGFR-Mutated Advanced NSCLC: A Patient–Care Team Journey Authors: Raffaele Califano, MD; Emma Halkyard, RN; Gini Harrison, PhD

https://www.medscape.org/viewarticle/1002547_sidebar7

Conditioning Regimens for HSCT in AML/MDS: Balancing Strategies for Improved Outcomes Authors: Mohamad Mohty, MD, PhD; Raynier Devillier, MD, PhD; Filippo Milano, MD, PhD; Friedrich Stölzel, MD

https://www.medscape.org/viewarticle/1002561_sidebar4

ASCO 2025: How Emerging Therapies Are Reshaping the Treatment Landscape in Endometrial Cancer Ursula A. Matulonis, MD | June 24, 2025

https://www.medscape.com/viewarticle/mdangle-asco-2025-endometrial-cancer-clinical-impact-2025a100010l

Prostate Cancer Highlights From ASCO 2025 Oliver Sartor, MD | June 24, 2025

https://www.medscape.com/viewarticle/prostate-cancer-updates-treatment-asco-2025-2025a100010w

18th International Conference on Malignant Lymphoma (ICML) 2025

https://www.medscape.com/viewcollection/37821

Liver Transplantation May Reduce Colorectal Neoplasia Risk in PSC-IBD Edited by Manasi Talwadekar June 24, 2025

https://www.medscape.com/viewarticle/liver-transplantation-may-reduce-colorectal-neoplasia-risk-2025a1000gr0

Strength Training Can Improve Lymphedema in Breast Cancer Edited by Gargi Mukherjee June 24, 2025

https://www.medscape.com/viewarticle/strength-training-can-improve-lymphedema-breast-cancer-2025a1000gsh

PD-L1 Did Not Predict Immunotherapy Benefit in Cervical Cancer Christos Evangelou, MSc, PhD June 24, 2025

https://www.medscape.com/viewarticle/pd-l1-did-not-predict-immunotherapy-benefit-cervical-cancer-2025a1000guz ESMO Gynecological (ESMO Gyn) Cancers Congress 2025 https://www.medscape.com/viewcollection/37812

Blood-Based KRAS Testing Fails in Low-Grade Ovarian Cancer Christos Evangelou, MSc, PhD June 24, 2025

https://www.medscape.com/viewarticle/blood-based-kras-testing-fails-low-grade-ovarian-cancer-2025a1000gyi ESMO Gynecological (ESMO Gyn) Cancers Congress 2025 https://www.medscape.com/viewcollection/37812

American Diabetes Association (ADA) 85th Scientific Sessions June 20 - 23, 2025 | Chicago, Illinois +...

https://www.medscape.com/viewcollection/37830?ecd=WNL_conf_endo_ADA-SPON_250623_MSCPEDIT_etid7517819&uac=148436CN&impID=7517819

Educating, Empowering, and Engaging: A Focus on HER2-Activating Mutations in NSCLC Authors: Eric K. Singhi, MD; Thomas Newsom-Davis, FRCP, PhD; Soo-Ryum (Stewart) Yang, MD

https://www.medscape.org/viewarticle/1002375?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250624-OUS-HONC-1002375-cta

Flood Preparedness and Coping ++++

https://www.ready.gov/floods?utm_source=SAMHSA&utm_campaign=cf3a708103-EMAIL_CAMPAIGN_2025_05_20_04_11_COPY_02&utm_medium=email&utm_term=0_-845dbb9bcb-167840245 Flood Preparedness and Coping Whether from heavy rain, snowmelt, or hurricanes, floods are the most common disaster in the United States. The National Weather Service has noted that floods cause more damage per year than any other type of weather-related disaster (with a cost of about $8 billion), and the National Oceanic and Atmospheric Administration reports that flooding is second only to heat in the number of deaths it causes each year. https://www.weather.gov/afc/FloodSafety?utm_source=SAMHSA&utm_campaign=cf3a708103-EMAIL_CAMPAIGN_2025_05_20_04_11_COPY_02&utm_medium=email&utm_term=0_-845dbb9bcb-167840245 This month, as we enter summer storm season, the SAMHSA Disaster Technical Assistance Center (DTAC) is sharing information on how to prepare for and cope with floods. The resources below contain information on how to prepare before floods occur, what to do during an evacuation, and how to support behavioral health and well-being, including children’s well-being, following floods. We also share tools for families to help support resilience and recovery after floods. https://www.noaa.gov/jetstream/thunderstorms/flood?utm_source=SAMHSA&utm_campaign=cf3a708103-EMAIL_CAMPAIGN_2025_05_20_04_11_COPY_02&utm_medium=email&utm_term=0_-845dbb9bcb-167840245 Flood Safety This American Red Cross web page covers floods, including links to active financial assistance programs for recent flooding events. It also provides flood preparedness videos in English, Spanish, and American Sign Language; a flood safety checklist in a variety of languages; and preparation tips for the whole family, including family members with disabilities and pets. Finally, it includes tips on how you can prevent injuries and protect your health after a flood. https://www.redcross.org/get-help/how-to-prepare-for-emergencies/types-of-emergencies/flood.html?utm_source=SAMHSA&utm_campaign=cf3a708103-EMAIL_CAMPAIGN_2025_05_20_04_11_COPY_02&utm_medium=email&utm_term=0_-845dbb9bcb-167840245

Tips for People With Dementia

https://www.alzheimers.gov/life-with-dementia/tips-dementia?&utm_source=nia-eblast&utm_medium=email&utm_campaign=general-20250624#safety-tips-for-people-living-with-dementia

Annihilating PFAS with an AI-designed enzyme Using artificial intelligence and machine learning, a team of researchers engineered an enzyme to degrade toxic PFAS molecules — and they’re only in high school.

https://www.drugdiscoverynews.com/annihilating-pfas-with-an-ai-designed-enzyme-16465?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_TbTk8a85tXjX1KhJkl7Z2Hy9VvbtBi2ReK8GNGgaWLvuj0XEnQF4rLbyI4ugT9B1C_X7bdc4YLlsXODbqu7Xd-AJszA&_hsmi=368156014&utm_content=368156014&utm_source=hs_email

Collaborative Care: Navigating Multidisciplinary Management of CLL and MCL for Optimal Patient Outcomes Authors: Jennifer A. Woyach, MD; Peter Dreger, MD; Sanam Loghavi, MD; Josie Montegaard, MSN, AGNP-BC

https://www.medscape.org/viewarticle/1002602?sso=true&impID=7520945&uac=148436CN&src=wnl_tpal_250624_mscpedu

Understanding the Evolving Landscape of Care in mCRPC: A Journal Club Session Authors: Bertrand Tombal, MD, PhD; Pedro C. Barata, MD, MSc, FACP

https://www.medscape.org/viewarticle/1002348?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250624-OUS-HONC-1002348-cta

15 Fingernail and Toenail Abnormalities: Indicators of Patient Health

https://reference.medscape.com/slideshow/fingernail-abnormalities-6002456?ecd=wnl_tp10_daily_250621_MSCPEDIT_etid7511440&uac=148436CN&impID=7511440

Staying Ahead: Essential Updates on Congenital Syphilis for Clinical Practice Authors: Ryan Rochat, MD, PhD, MS

https://www.medscape.org/viewarticle/1002381?ecd=suppd_owh_distr_mscpedu&utm_medium=email&utm_source=govdelivery Health care providers, are you aware of the latest strategies for managing congenital syphilis? The U.S. Department of Health and Human Services, Office on Women’s Health is announcing a new continuing medical education/continuing education (CME/CE) activity: “Staying Ahead: Essential Updates on Congenital Syphilis for Clinical Practice.” This new accredited course offers the latest evidence-based guidance for health care providers on identifying and managing congenital syphilis in infants. You’ll learn how to: Optimize the transition from neonatal and postnatal to pediatric care Support infants and their families navigating congenital syphilis Assess your learning needs regarding evidence-based management of congenital syphilis If you’re a health care provider committed to advancing women’s and infant health, this is an opportunity to expand your knowledge and improve patient care. Earn continuing education credit while making a real impact.

RARE Revolution RARE Bite

https://editions.rarerevolutionmagazine.com/html5/reader/production/default.aspx?pubname=&edid=7dff7463-ab1c-41ec-978b-d13d7299390a

A movement born from silence: The global mission to treat CTNNB1 syndrome

https://rarerevolutionmagazine.com/a-movement-born-from-silence-the-global-mission-to-treat-ctnnb1-syndrome/

Three ways AI is changing paediatric genomic medicine

https://rarerevolutionmagazine.com/three-ways-ai-is-changing-paediatric-genomic-medicine/

Teen screen time linked to poor sleep and brain changes

https://www.news-medical.net/news/20250623/Teen-screen-time-linked-to-poor-sleep-and-brain-changes.aspx

Cannabidiol may help reduce problematic behaviors in autistic boys

https://www.news-medical.net/news/20250623/Cannabidiol-may-help-reduce-problematic-behaviors-in-autistic-boys.aspx

New oral drug shows promise for type 2 diabetes and obesity without side effects

https://www.news-medical.net/news/20250623/New-oral-drug-shows-promise-for-type-2-diabetes-and-obesity-without-side-effects.aspx

Stem Cell-Derived Islets Still Producing Insulin at 1 Year Miriam E. Tucker | June 21, 2025

https://www.medscape.com/viewarticle/stem-cell-derived-islets-still-producing-insulin-1-year-2025a1000glb?ecd=wnl_edit_tpal_etid7516580&uac=148436CN&impID=7516580

Population-Level Weight Loss Seen With Primary Care Protocol Alicia Ault June 21, 2025

https://www.medscape.com/viewarticle/population-level-weight-loss-seen-primary-care-protocol-2025a1000gli?ecd=wnl_edit_tpal_etid7516580&uac=148436CN&impID=7516580

Novel GLP-1 Agonist Promotes Safe and Effective Weight Loss Heidi Splete | June 21, 2025

https://www.medscape.com/viewarticle/novel-glp-1-agonist-promotes-safe-and-effective-weight-loss-2025a1000gll?ecd=wnl_edit_tpal_etid7516580&uac=148436CN&impID=7516580

ASCO 2025: The Impact of Advances in Trials, Biomarkers, and Therapies in Prostate Cancer Petros Grivas, MD, PhD | June 23, 2025

https://www.medscape.com/viewarticle/mdangle-asco-2025-prostate-cancer-clinical-impact-2025a10000ip

Multitasking ctDNA Helps Guide Lymphoma Treatment Nancy A. Melville | June 23, 2025

https://www.medscape.com/viewarticle/multitasking-ctdna-helps-guide-lymphoma-treatment-2025a1000gm4

NHL: 2nd Generation CAR T Shows Benefit Nancy A. Melville | June 23, 2025

https://www.medscape.com/viewarticle/nhl-2nd-generation-car-t-shows-benefit-2025a1000gn0

Which Second-Line Therapy Is Better for Right-Sided Metastatic CRC? Edited by Gargi Mukherjee June 23, 2025

https://www.medscape.com/viewarticle/which-second-line-therapy-better-right-sided-metastatic-crc-2025a1000gns

Personalized Care Is Pivotal: Navigating the Evolving Landscape for Advanced Urothelial Carcinoma Authors: Alison J. Birtle, MD, FRCP, FRCR, DipLCM; Philippe Barthélémy, MD, PhD; Enrique Grande, MD, PhD; Syed A. Hussain, MBBS, MSc, MD

https://www.medscape.org/viewarticle/1002453?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250622-OUS-HONC-1002453-cta

The bloom and the breathless: the rising burden of pollen allergy

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00259-7/fulltext?dgcid=raven_jbs_etoc_email https://www.thelancet.com/journals/eclinm/issue/vol84nonull/PIIS2589-5370(25)X0005-5

Advancing Cancer Care and Research Together

Enhancing the response to avian influenza in the US and globally

https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(25)00110-3/fulltext?dgcid=hubspot_update_feature_updatealerts_lanam&utm_campaign=update-lanam&utm_medium=email&_hsenc=p2ANqtz--zc0JgAV1ifF76-99oRfd-Pi849en5NtEcKl7P9jKd4AlSNtG4-8I8nvG9lBxET2JHPDznFAn8vBoQG7gNeblqBsT_tA&_hsmi=367964817&utm_content=367727188&utm_source=hs_email

Cyberbullying, mental health, and substance use experimentation among early adolescents: a prospective cohort study

https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(25)00012-2/fulltext?dgcid=hubspot_update_feature_updatealerts_lanam&utm_campaign=update-lanam&utm_medium=email&_hsenc=p2ANqtz-9BcLHgnrGHk7-gw2AnIJNm7ZwTVSbef-DtThEMXuupdS_36u6OEz4egHOawNQZSz5QXNLoDXgDV_G1BsuMu5Wttd85YA&_hsmi=367964817&utm_content=367727188&utm_source=hs_email

FDA grants accelerated approval to datopotamab deruxtecan-dlnk for EGFR-mutated non-small cell lung cancer

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-accelerated-approval-datopotamab-deruxtecan-dlnk-egfr-mutated-non-small-cell-lung-cancer?utm_medium=email&utm_source=govdelivery

Study links sleep heart rate variability to stroke and depression risk

https://www.news-medical.net/news/20250620/Study-links-sleep-heart-rate-variability-to-stroke-and-depression-risk.aspx

Diabetes medication shows promise in cutting migraine days by more than half

https://www.news-medical.net/news/20250620/Diabetes-medication-shows-promise-in-cutting-migraine-days-by-more-than-half.aspx

Healthy gut microbiome before chemo could help protect breast cancer patients against cardiotoxicity

https://www.news-medical.net/news/20250621/Healthy-gut-microbiome-before-chemo-could-help-protect-breast-cancer-patients-against-cardiotoxicity.aspx

Hydration tips for active lifestyles in warmer weather

https://www.news-medical.net/news/20250621/Hydration-tips-for-active-lifestyles-in-warmer-weather.aspx

UK heatwave expected to cause 570 deaths by end of weekend

https://www.news-medical.net/news/20250621/UK-heatwave-expected-to-cause-570-deaths-by-end-of-weekend.aspx

How Doctors Use Travel to Heal Themselves Dina Cheney ++++

https://www.medscape.com/viewarticle/how-doctors-use-travel-heal-themselves-2025a1000896?ecd=mkm_ret_250621_mscp_newf_perspectives-mentalhealth_etid7510633&uac=148436CN&impID=7510633 How a Mindset Shift Can Transform the Way You Practice Molly MacGilbert https://www.medscape.com/viewarticle/how-mindset-shift-can-transform-way-you-practice-2024a1000az0?ecd=mkm_ret_250621_mscp_newf_perspectives-mentalhealth_etid7510633&uac=148436CN&impID=7510633 June 12, 2024 Why These Doctors Trade Prestige for Happiness Amanda Loudin https://www.medscape.com/viewarticle/990900?ecd=mkm_ret_250621_mscp_newf_perspectives-mentalhealth_etid7510633&uac=148436CN&impID=7510633 April 18, 2023 Always On Call: Why You Can’t Unplug and How You Finally Can Dina Cheney https://www.medscape.com/viewarticle/always-call-why-you-cant-unplug-and-how-you-finally-can-2025a1000553?ecd=mkm_ret_250621_mscp_newf_perspectives-mentalhealth_etid7510633&uac=148436CN&impID=7510633

Knee OA Pain? Yoga, Strengthening Exercises May Help Equally Edited by Manasi Talwadekar ++++

https://www.medscape.com/viewarticle/knee-oa-pain-yoga-strengthening-exercises-may-help-equally-2025a10008kb?ecd=mkm_ret_250621_mscpmrk-OUS_ExcNews_etid7510218&uac=148436CN&impID=7510218 Early Care Matters in the Stress-Chronic Pain Connection Manuela Callari https://www.medscape.com/viewarticle/early-care-matters-stress-chronic-pain-connection-2025a1000b27?ecd=mkm_ret_250621_mscpmrk-OUS_ExcNews_etid7510218&uac=148436CN&impID=7510218 Nonsurgical Interventions Show Modest Long-Term Benefits for Chronic Low Back Pain Edited by Manasi Talwadekar https://www.medscape.com/viewarticle/nonsurgical-interventions-show-modest-long-term-benefits-2025a1000fme?ecd=mkm_ret_250621_mscpmrk-OUS_ExcNews_etid7510218&uac=148436CN&impID=7510218 June 11, 2025 How to Mentally Reset After a Tough Shift Nayiri Guedikian, MD, MPH https://www.medscape.com/viewarticle/how-mentally-reset-after-tough-shift-2025a1000fgl?ecd=mkm_ret_250621_mscpmrk-OUS_ExcNews_etid7510218&uac=148436CN&impID=7510218 | June 11, 2025

Clinical Case Scenarios in HR-Positive, HER2-Negative Early Breast Cancer: Assess the Risk of Recurrence and Eligibility for Adjuvant Therapy Authors: Seth Wander, MD, PhD; Manali Bhave, MD

https://www.medscape.org/viewarticle/1002194_sidebar8?sso=true&uac=148436CN&ecd=mkm_ret_250621_mscpmrk-ES_CME_etid7505456&impID=7505456

The Patient With HR+/HER2- Early Breast Cancer: The Importance of Communication at All Stages of Management Authors: Shaheenah Dawood, MBBCh, MPH, FACP

https://www.medscape.org/viewarticle/1002462_sidebar11?sso=true&uac=148436CN&ecd=mkm_ret_250621_mscpmrk-ES_CME_etid7505456&impID=7505456

Shaping the Future of Muscle-Invasive Bladder Cancer Care: Immunotherapy in Focus Authors: Andrea Necchi, MD; James W. F. Catto, MB, ChB, PhD, FRCS; Enrique Grande, MD, PhD

https://www.medscape.org/viewarticle/1002445_sidebar10?sso=true&uac=148436CN&ecd=mkm_ret_250621_mscpmrk-ES_CME_etid7505456&impID=7505456

Personalized Care Is Pivotal: Navigating the Evolving Landscape for Advanced Urothelial Carcinoma Authors: Alison J. Birtle, MD, FRCP, FRCR, DipLCM; Philippe Barthélémy, MD, PhD; Enrique Grande, MD, PhD; Syed A. Hussain, MBBS, MSc, MD

https://www.medscape.org/viewarticle/1002453_sidebar9?sso=true&uac=148436CN&ecd=mkm_ret_250621_mscpmrk-ES_CME_etid7505456&impID=7505456

Comprehensive and Personalized Approach to Managing mHSPC: Fitting the Right Pieces for Each Patient Authors: Fred Saad, MD, FRCS; Elena Castro, MD, PhD

https://www.medscape.org/viewarticle/1002043_sidebar7?sso=true&uac=148436CN&ecd=mkm_ret_250621_mscpmrk-ES_CME_etid7505456&impID=7505456

Evolving Treatment Landscape for mHSPC: Latest Clinical Data and Implications for Practice Authors: Fred Saad, MD, FRCS; Neal Shore, MD, FACS

https://www.medscape.org/viewarticle/1001957_sidebar7?sso=true&uac=148436CN&ecd=mkm_ret_250621_mscpmrk-ES_CME_etid7505456&impID=7505456

Exploring Novel Combinations in mCRPC Care: Radioligands and Beyond Authors: Alison Birtle, MD, MBBS, FRCR, FRCP; Tony Collier, BEM; Ray McDermott, MD, PhD; Kambiz Rahbar, MD

https://www.medscape.org/viewarticle/1001854_sidebar10?sso=true&uac=148436CN&ecd=mkm_ret_250621_mscpmrk-ES_CME_etid7505456&impID=7505456

Decoding PD-L1 Scoring: Guiding Immunotherapy for Gastroesophageal Cancers Authors: Samuel J. Klempner, MD, FASCO; Matteo Fassan, MD, PhD; Mar Iglesias, MD

https://www.medscape.org/viewarticle/1002476_sidebar10?sso=true&uac=148436CN&ecd=mkm_ret_250621_mscpmrk-ES_CME_etid7505456&impID=7505456

‘A Lot More Still Needs to Be Done’: Medscape Oncologists and Suicide Report 2025

https://www.medscape.com//slideshow/2025-oncology-suicide-report-6018124?ecd=WNL_physrep_250621_MSCPEDIT_suicide-t1_etid7511594&uac=148436CN&impID=7511594

Weekly Rundown: New FDA voucher program to speed up drug review A blood test for organ rejection, another death related to gene therapy for Duchenne muscular dystrophy, a setback for AbbVie, and more led the news this week.

https://www.drugdiscoverynews.com/weekly-rundown-new-fda-voucher-program-to-speed-drug-review-16461?utm_campaign=DDN_Newsletter_Science%20Spotlight&utm_medium=email&_hsenc=p2ANqtz-8UUT8KutkPx_Qu7qKga2hsKPm29InoVrA_isVtZfwuTL_lCDDbEnM8SNwf_KgL9_8waAGIL19VW2GCjmAD9bR6CSYJZQ&_hsmi=367735560&utm_content=367735560&utm_source=hs_email

Advancing Patient-Centered Care in mCRPC: Exploring PARP Inhibitor Combinations Authors: Neeraj Agarwal, MD, FASCO; Karim Fizazi, MD, PhD

https://www.medscape.org/viewarticle/1002353?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250621-OUS-HONC-1002353-cta

Shaping the Future of Muscle-Invasive Bladder Cancer Care: Immunotherapy in Focus Authors: Andrea Necchi, MD; James W. F. Catto, MB, ChB, PhD, FRCS; Enrique Grande, MD, PhD

https://www.medscape.org/viewarticle/1002445?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250622-OUS-HONC-1002445-cta

Collaborative Management of EGFR-Mutated Advanced NSCLC: A Patient–Care Team Journey Authors: Raffaele Califano, MD; Emma Halkyard, RN; Gini Harrison, PhD

https://www.medscape.org/viewarticle/1002547_sidebar5?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_250622-1002547_es-lang_honc

Honouring the amyotrophic lateral sclerosis research pledge

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00166-8/fulltext?dgcid=raven_jbs_etoc_email https://www.thelancet.com/journals/laneur/issue/vol24no7/PIIS1474-4422(25)X0007-7

Copenhagen Declaration: a transformative vision for global diabetes

https://www.thelancet.com/journals/landia/issue/vol13no7/PIIS2213-8587(25)X0007-3

Childhood obesity: prioritising a healthy start

https://www.thelancet.com/journals/landia/article/PIIS2213-8587(25)00169-X/fulltext?dgcid=raven_jbs_etoc_email

Translating AI innovation into clinical practice The Lancet Rheumatology

https://www.thelancet.com/journals/lanrhe/issue/vol7no7/PIIS2665-9913(25)X0007-2

Predicting the risk of subsequent progression in patients with systemic sclerosis-associated interstitial lung disease with progression: a multicentre observational cohort study

https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(25)00026-8/abstract?dgcid=raven_jbs_etoc_feature_lanrhe

The mpox response: African leadership, global responsibility

https://www.thelancet.com/journals/lancet/issue/vol405no10496/PIIS0140-6736(25)X0025-8

Stop Gaslighting, Start Greenlighting By Ivanhoe Broadcast News on June 27, 2025

https://www.ivanhoe.com/?p=35627&preview=1&_ppp=e0b79563ee

Dementia Defense: 4 Surprising Ways To Prevent Alzheimer’s By Ivanhoe Broadcast News on June 26, 2025

https://www.ivanhoe.com/?p=35624&preview=1&_ppp=4fa278c1bb

Turning A Promotion Loss Into A Career Win! By Ivanhoe Broadcast News on June 25, 2025

https://www.ivanhoe.com/?p=35621&preview=1&_ppp=386a191fe5

Cost Of Care: Financial Support For Family Caregivers By Ivanhoe Broadcast News on June 24, 2025

https://www.ivanhoe.com/?p=35618&preview=1&_ppp=db9d1ffb80

Eat With Caution: Cancer-Causing Chemicals In Your Food By Ivanhoe Broadcast News on June 23, 2025

https://www.ivanhoe.com/?p=35614&preview=1&_ppp=591d53a1e5

Myelofibrosis-Associated Anemia: Burden, Management, and Future Directions Authors: Francesca Palandri, MD; Jean-Jacques Kiladjian, MD, PhD; Jon Mathias

https://www.medscape.org/viewarticle/1002370?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250621-OUS-HONC-1002370-cta

What Your Breathing Says About Your Mental Health F. Perry Wilson, MD, MSCE | June 12, 2025

https://www.medscape.com/viewarticle/what-your-breathing-says-about-your-mental-health-2025a1000flb?ecd=mkm_ret_250621_mscpmrk_psych_top-content_etid7506298&uac=148436CN&impID=7506298

Frequent Nightmares Linked to Faster Aging, Premature Death Deborah Brauser April 08, 2025

https://www.medscape.com/viewarticle/frequent-nightmares-linked-faster-aging-premature-death-2025a10008ea?ecd=WNL_conf_neuro_Sleep-SPON_250621_MSCPEDIT_etid7513551&uac=&impID=7513551

Narcolepsy Clinical Presentation

https://emedicine.medscape.com/article/1188433-clinical?ecd=WNL_conf_neuro_Sleep-SPON_250621_MSCPEDIT_etid7513551&uac=&impID=7513551

Insomnia Workup

https://emedicine.medscape.com/article/1187829-workup?ecd=WNL_conf_neuro_Sleep-SPON_250621_MSCPEDIT_etid7513551&uac=&impID=7513551

Sleep Terrors

https://emedicine.medscape.com/article/914360-overview?ecd=WNL_conf_neuro_Sleep-SPON_250621_MSCPEDIT_etid7513551&uac=&impID=7513551

SLEEP 2025 June 8-11, 2025 | Seattle, Washington

https://www.medscape.com/viewcollection/37809?ecd=WNL_conf_neuro_Sleep-SPON_250621_MSCPEDIT_etid7513551&uac=&impID=7513551

Obstetrics, Gynaecology, & Women’s Health

https://www.thelancet.com/collections/obstetrics-gynaecology-womens-health?dgcid=hubspot_email_infocusalerts-obgyn_feature&parent=001603&startPage=&ContentItemType=fla&utm_campaign=infocusalerts-obgyn&utm_medium=email&_hsenc=p2ANqtz-91qlq4UaTpgyjViNcOjaX1_W9I5C2c391W2HZj7H2W9KxX-STC7A7H8NLx77mqXQO0GcvwPLxQuAR7Xq5vGPM5jlYoIw&_hsmi=367774517&utm_content=367087652&utm_source=hs_email

U.S. Selected Practice Recommendations for Contraceptive Use, 2024 Authors: Kathryn M. Curtis, PhD; Antoinette T. Nguyen, MD; Naomi K. Tepper, MD; Lauren B. Zapata, PhD; Emily M. Snyder, MPH; Kendra Hatfield-Timajchy, PhD; Katherine Kortsmit, PhD; Megan A. Cohen, MD; Maura K. Whiteman, PhD

https://www.medscape.org/viewarticle/1002478?sso=true&impID=7514187&uac=148436CN&src=wnl_tpal_250621_mscpedu

Targeting ST6Gal-I shows promise in reducing Alzheimer’s disease pathology

https://www.news-medical.net/news/20250620/Targeting-ST6Gal-I-shows-promise-in-reducing-Alzheimere28099s-disease-pathology.aspx

Immune changes predict heart risks in cancer patients on checkpoint inhibitors

https://www.news-medical.net/news/20250620/Immune-changes-predict-heart-risks-in-cancer-patients-on-checkpoint-inhibitors.aspx

Cord blood proteins help detect early sepsis in preterm infants

https://www.news-medical.net/news/20250620/Cord-blood-proteins-help-detect-early-sepsis-in-preterm-infants.aspx

Bedtime screen habits linked to poor sleep in tweens

https://www.news-medical.net/news/20250620/Bedtime-screen-habits-linked-to-poor-sleep-in-tweens.aspx

New study reveals how bedding insulation impacts sleep quality

https://www.news-medical.net/news/20250620/New-study-reveals-how-bedding-insulation-impacts-sleep-quality.aspx

Tdap Vaccine: What It Is and What It Protects Against

As vaccine-preventable diseases re-emerge, the Tdap vaccine remains a cornerstone of maternal and public health, protecting both newborns and communities through timely immunization and booster strategies. https://www.news-medical.net/health/Tdap-Vaccine-What-It-Is-and-What-It-Protects-Against.aspx

Higher ocean microplastics linked to more diabetes, stroke, and heart disease

https://www.news-medical.net/news/20250619/Higher-ocean-microplastics-linked-to-more-diabetes-stroke-and-heart-disease.aspx

Journal Club: Latest Advances in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Authors: Claudia Sommer, MD; Jeffrey Allen, MD; Anna Kostera-Pruszczyk, MD, PhD

https://www.medscape.org/viewarticle/1002373_sidebar6?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_250619-ES_LANG-NEUR-1002373-cta

Exploring Novel Combinations in mCRPC Care: Radioligands and Beyond Authors: Alison Birtle, MD, MBBS, FRCR, FRCP; Tony Collier, BEM; Ray McDermott, MD, PhD; Kambiz Rahbar, MD

https://www.medscape.org/viewarticle/1001854_sidebar10?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_250619-ES_LANG-HONC-1001854-cta

The Rise of Protein Degraders for Hematologic Malignancies: Exploring the Latest Data From ASH 2024 Authors: Sagar Lonial, MD, FACP; Constatine Tam, MBBS, MD, FRACP, FRCPath; Julio Chavez, MD, MS

https://www.medscape.org/viewarticle/1002295?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250619-OUS-HONC-1002295-cta

Hypoparathyroidism By: Madaline Spencer| Published on: Jan 12, 2025

https://checkrare.com/hypoparathyroidism/

Rare Disease Recognition and Awareness Days By: Jake Ciszewski| Updated on: Jun 6, 2025 +++ +++ +++ +

https://checkrare.com/rare-disease-awareness-days-and-recognition-page/ CLINICAL PERSPECTIVES Digital Voice Analysis as a Biomarker of Acromegaly https://checkrare.com/digital-voice-analysis-as-a-biomarker-of-acromegaly/ A recent study published in The Journal of Clinical Endocrinology & Metabolism analyzed the use of digital voice analysis as a biomarker of acromegaly. Long-term Efficacy of TransCon PTH to Treat Hypoparathyroidism https://checkrare.com/long-term-efficacy-of-transcon-pth-to-treat-hypoparathyroidism/ A new study by Clarke and colleagues published in the Journal of Clinical Endocrinology & Metabolism highlights the safety and efficacy of TransCOn PTH (palopegteriparatide) to treat adults with hypoparathyroidism. Prader-Willi Syndrome: A Caregiver’s Perspective https://checkrare.com/prader-willi-syndrome-a-caregivers-perspective/ Kelly Guillo, Board Member of the Prader-Willi Syndrome Association in Georgia, discusses Prader-Willi syndrome (PWS) from the perspective of a caregiver. The Undiagnosed Disease Network https://checkrare.com/the-undiagnosed-disease-network/ Kimberly LeBlanc, Genetic Counselor, Director of the Undiagnosed Diseases Network (UDN) Coordinating Center at Harvard Medical School, discusses approaching variants of uncertain significance in rare diseases. Ethical Concerns in Rare Diseases and Expanded Access Programs https://checkrare.com/ethical-concerns-in-rare-diseases-and-expanded-access-programs/ Alison Bateman-House, PhD, Assistant Professor Division of Medical Ethics at NYU Grossman School of Medicine, discusses ethical concerns in rare diseases and expanded access programs. The Diversity of Patient Advocacy Group Initiatives https://checkrare.com/the-diversity-of-patient-advocacy-group-initiatives/ Connie Lee, PsyD, Chief Executive Officer of Alliance to Cure Cavernous Malformations, discusses cerebral cavernous malformation (CMM) and the diversity of patient advocacy group initiatives. Mental Health and the Rare Disease Community https://checkrare.com/mental-health-and-the-rare-disease-community/ Al Freedman, PhD, Rare Disease Psychologist and Rare Dad, discusses how industry partners can support the mental health of rare disease communities.  Challenges Faced by Rare Disease Patients in India https://checkrare.com/challenges-faced-by-rare-disease-patients-in-india/ Ramaiah Muthyala, PhD, Research Associate Professor at University of Minnesota and President and CEO of Indian Organization for Rare Diseases (IORD), discusses the challenges faced by rare disease patients in India. Global Genes’ Patient and Advocate Initiatives https://checkrare.com/global-genes-patient-and-advocate-initiatives/ Daniel DeFabio, Director of Community Engagement and Education at Global Genes, Co-Founder of Disorder: The Rare Disease Film Festival, and rare disease father, discusses Global Genes’ patient and advocate initiatives. Newborn Screening Update Following RFK’s Removal of Advisory Committee https://checkrare.com/newborn-screening-update-following-rfks-removal-of-advisory-committee/ Dean Suhr, President and co-founder of the MLD Foundation, discusses newborn screening updates and plans for gaining recommended uniform screening panel (RUSP) approval.

Patient-Centered Paroxysmal Nocturnal Hemoglobinuria Treatment and the Role of Terminal Complement Inhibitors Authors: Regis Peffault de Latour, MD, PhD; Talha Munir, MBChB, PhD; Rachel Paine; Richard Kelly, MBChB, PhD; Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath

https://www.medscape.org/viewarticle/1002332?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250620-OUS-HONC-1002332-cta

American Society of Clinical Oncology (ASCO) 2025 May 30 - June 03, 2025 | Chicago, Illinois and Virtual +++++

American Society of Clinical Oncology (ASCO) 2025 May 30 - June 03, 2025 | Chicago, Illinois and Virtual https://www.medscape.com/viewcollection/37796?ecd=WNL_onc_ASCO-SPON_250620_MSCPEDIT_etid7510524&uac=148436CN&impID=7510524 Hematologic Cancers OS Data From CARTITUDE-1: A Cure for Myeloma? https://www.medscape.com/viewarticle/q-does-long-term-os-data-cartitude-1-portend-cure-myeloma-2025a1000foh?ecd=WNL_onc_ASCO-SPON_250620_MSCPEDIT_etid7510524&uac=148436CN&impID=7510524 Q&A: New Myeloma Bispecific Rivals CAR T in Early Data https://www.medscape.com/viewarticle/q-new-myeloma-bispecific-rivals-car-t-early-data-2025a1000g9r?ecd=WNL_onc_ASCO-SPON_250620_MSCPEDIT_etid7510524&uac=148436CN&impID=7510524 Can New Combo Fill ‘Unmet Need’ in R/R Hodgkin Lymphoma? https://www.medscape.com/viewarticle/can-new-combo-fill-unmet-need-r-r-hodgkin-lymphoma-2025a1000fjc?ecd=WNL_onc_ASCO-SPON_250620_MSCPEDIT_etid7510524&uac=148436CN&impID=7510524 PVEK: A Game Changer in Rare, Deadly Blood Cancer? https://www.medscape.com/viewarticle/q-pvek-new-standard-care-rare-deadly-blood-cancer-2025a1000fog?ecd=WNL_onc_ASCO-SPON_250620_MSCPEDIT_etid7510524&uac=148436CN&impID=7510524

Sexual Effects Persist After Cervical Cancer Treatment Sharon Worcester +++++++

Artificial Intelligence Enhances Prostate Cancer Detection in MRI Study Edited by Gargi Mukherjee https://www.medscape.com/viewarticle/artificial-intelligence-enhances-prostate-cancer-detection-2025a1000g8i Medscape UK June 20, 2025 Darzalex Monotherapy OK'd for Smoldering Multiple Myeloma Dr Rob Hicks MBBS DRCOG MRCGP https://www.medscape.com/viewarticle/darzalex-monotherapy-okd-smoldering-multiple-myeloma-2025a1000gjo | June 20, 2025 Exceptional Use Recommendation for Nuclear Emergency Drug Sheena Meredith, MBBS, MPhil https://www.medscape.com/viewarticle/exceptional-use-recommendation-nuclear-emergency-drug-2025a1000gip June 20, 2025 DLBCL: Tumor Cell Signatures Predict CAR-T Success Randy Dotinga https://www.medscape.com/viewarticle/dlbcl-tumor-cell-signatures-predict-car-t-success-2025a1000gi4 | June 20, 2025 Sexual Effects Persist After Cervical Cancer Treatment Sharon Worcester https://www.medscape.com/viewarticle/sexual-effects-persist-after-cervical-cancer-treatment-2025a1000gh7 Do Tattoos Pose a Cancer Risk? Stephen A. Hoption Cann, PhD https://www.medscape.com/viewarticle/do-tattoos-pose-cancer-risk-2025a1000fkh | June 20, 2025 Watch for These Lung Cancer Signs in Nonsmokers Neena Chandrasekaran, MD https://www.medscape.com/viewarticle/watch-these-lung-cancer-signs-nonsmokers-2025a1000g3t | June 20, 2025 | June 20, 2025

Europe Recommends Stem Cell Therapy for Blood Cancers Dr Rob Hicks MBBS DRCOG MRCGP | June 20, 2025

https://www.medscape.com/viewarticle/europe-recommends-stem-cell-therapy-blood-cancers-2025a1000gja

Cancer Concerns Spark Caution Over Weight-Loss Injections Dr Sheena Meredith Medscape UK June 20, 2025

https://www.medscape.com/viewarticle/cancer-concerns-spark-caution-over-weight-loss-injections-2025a1000gju

Clinical Trials in CLL and MCL: Expert In-Depth Analysis Authors: Chan Cheah, MBBS, DMSc; Nirav N. Shah, MD; Jennifer A. Woyach, MD

https://www.medscape.org/viewarticle/1002400?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250620-OUS-HONC-1002400-cta

Congenital Anomalies of the Genitourinary System

https://reference.medscape.com/slideshow/congenital-anomalies-gs-6009085?ecd=wnl_critimg_250620_mscpref_etid7508689&uac=148436CN&impID=7508689

Most Read Papers - Cancer Science & Oncogenesis

Mycosis Fungoides, Sézary Syndrome, and Cutaneous B-Cell Lymphomas: 2025 Update on Diagnosis, Risk-Stratification, and Management. Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for cla.. Jun 10, 2025: American Journal of Hematology https://read.qxmd.com/collection/1133?ecd=wnl_readmost_250620

ASCO 2025: Clinical Impact of Practice-Changing Updates in Advanced NSCLC Isabel Preeshagul, DO, MBS | June 18, 2025

https://www.medscape.com/viewarticle/mdangle-asco-2025-advanced-nsclc-clinical-impact-2025a10000et

Is It Worth Adding Chemo to ICI for NSCLC in Older Adults? M. Alexander Otto, PA, MMSc | June 19, 2025

https://www.medscape.com/viewarticle/it-worth-adding-chemo-ici-nsclc-older-adults-2025a1000geb

Empagliflozin Not Linked to Urinary Tract Cancer in T2D Edited by Devyani Gholap Medscape UK June 19, 2025

https://www.medscape.com/viewarticle/empagliflozin-not-linked-urinary-tract-cancer-t2d-2025a1000g4b

Can Modulation of the Microbiome Improve Cancer Immunotherapy Tolerance and Efficacy? Christine Kilgore June 19, 2025

https://www.medscape.com/viewarticle/can-modulation-microbiome-improve-cancer-immunotherapy-2025a1000gev

Genetics or Microenvironment: What Drives CLL Progression? Cristina Ferrario June 19, 2025

https://www.medscape.com/viewarticle/genetics-or-microenvironment-what-drives-cll-progression-2025a1000gf8

Migraine relief before a headache starts The drug, ubrogepant, mitigated many of the symptoms that precede the worst of a migraine and hinted at the condition’s origin.

https://www.drugdiscoverynews.com/migraine-relief-before-a-headache-starts-16453

A new type of injection could improve eye disease treatment To get drugs to reach the choroid and retina, ophthalmologists have relied on imperfect methods with drawbacks. Suprachoroidal delivery could be the fix

https://www.drugdiscoverynews.com/a-new-type-of-injection-could-improve-eye-disease-treatment-16458?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_PX74nU1K0Hy8RsuED8lQHYd-6w1MJ_l_b8xtJO6rw-pC6ZxxtxU2k8BsHnk74rULw4X9s2R-ATkd41nt_qkYvW5pJ1w&_hsmi=367579052&utm_content=367579052&utm_source=hs_email

Is a Hypocaloric Diet Safe and Effective for Long-Term Health? +++

Is a Hypocaloric Diet Safe and Effective for Long-Term Health? https://www.news-medical.net/health/Is-a-Hypocaloric-Diet-Safe-and-Effective-for-Long-Term-Health.aspx Salmonella Outbreak Linked to Shell Eggs: Scientific Perspective on the 2025 Outbreak https://www.news-medical.net/health/Salmonella-Outbreak-Linked-to-Shell-Eggs-Scientific-Perspective-on-the-2025-Outbreak.aspx The MIND Diet Explained: Foods That Fight Cognitive Decline https://www.news-medical.net/health/The-MIND-Diet-Explained-Foods-That-Fight-Cognitive-Decline.aspx

What matters more for diabetes risk: lifestyle or body weight?

https://www.news-medical.net/news/20250618/What-matters-more-for-diabetes-risk-lifestyle-or-body-weight.aspx

Editorial p701 Time to prioritise invasive fungal diseases The Lancet Infectious Diseases

https://www.thelancet.com/journals/laninf/issue/vol25no7/PIIS1473-3099(25)X0007-4

A promising annual shot might provide long term protection against HIV Jessica Hamzelou | MIT Technology Review | June 18, 2025

https://geneticliteracyproject.org/2025/06/18/a-promising-annual-shot-might-provide-long-term-protection-against-hiv/

What is ‘therapy speak’ and why is its proliferation so dangerous? Victor G. Petreca | Boston Globe | June 18, 2025

https://geneticliteracyproject.org/2025/06/18/what-is-therapy-speak-and-why-is-its-proliferation-so-dangerous/

Swallowing risk: The hidden dangers 7 of America’s most popular supplements Caroline Kee | Today | June 19, 2025

https://geneticliteracyproject.org/2025/06/19/swallowing-risk-the-hidden-dangers-7-of-americas-most-popular-supplements/

Appreciating music: What are the evolutionary links between humans and other animals Elizabeth Hlavinka | Salon | June 19, 2025

https://geneticliteracyproject.org/2025/06/19/appreciating-music-what-are-the-evolutionary-links-between-humans-and-other-animals/

Near-death experiences: Conversations with the Creator? Christian Jarrett | Science Focus | June 19, 2025

https://geneticliteracyproject.org/2025/06/19/near-death-experiences-conversations-with-the-creator/

Slowing malaria by treating mosquitoes

https://www.nih.gov/news-events/nih-research-matters/slowing-malaria-treating-mosquitoes

Cysteine restriction plays key role in weight loss

https://www.nih.gov/news-events/nih-research-matters/cysteine-restriction-plays-key-role-weight-loss

Y chromosome loss plays complex role in cancers

https://www.nih.gov/news-events/nih-research-matters/y-chromosome-loss-plays-complex-role-cancers

FDA halts new clinical trials that export Americans’ cells to foreign labs in hostile countries for genetic engineering Trials failed to inform participants about the international transfer.

https://www.nih.gov/news-events/news-releases/fda-halts-new-clinical-trials-export-americans-cells-foreign-labs-hostile-countries-genetic-engineering

Nordic Rare Disease Summit 2025 Act 2030: Pushing Boundaries for Rare September 16 & 17, 2025 Copenhagen, Denmark

https://nordicrarediseasesummit.org/ CORRECTION: Nordic Rare Disease Summit 2025, 16-17 September 2025 Dear Reader, Please find below a corrected version of the EURORDIS Monthly News that was circulated yesterday, Wednesday 18 June. The Nordic Rare Disease Summit 2025 will in fact take place on 16–17 September (not 16–17 July, as was incorrectly stated). We apologise for the error and thank you for your understanding.

A Year in Review of Antibody-Drug Conjugates for Breast Cancer: Trends, Practice, and Outlook Authors: Peter Schmid, MD, PhD, FRCP; Shanu Modi, MD; Erika P. Hamilton, MD; Nicola Fusco, MD

https://www.medscape.org/viewarticle/1002233?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250618-OUS-HONC-1002233-cta

Guiding Our Patient's Path: Managing First Relapse in Diffuse Large B-Cell Lymphoma Outside of CAR Ts Authors: Wendy Osborne, MBBS (Hons), MRCP, FRCPath; Natacha Bolaños; Gareth Gregory, MBBS, PhD; Gilles Salles, MD, PhD

https://www.medscape.org/viewarticle/1002120?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250617-OUS-HONC-1002120-cta

COVID-19 and Oral Antivirals: How to Define an Eligible Patient Authors: Marta Boffito, MD, PhD, FRSP, MBA; Jörg Schelling, MD, FESPCH

https://www.medscape.org/viewarticle/1002037?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250618-OUS-HONC-1002037-cta

Alcohol and health: time for Europe to sober up The Lancet Gastroenterology & Hepatology

https://www.thelancet.com/journals/langas/issue/vol10no7/PIIS2468-1253(25)X0006-6

Jun 2025 Volume 6Number 6: Effect of the vaginal live biotherapeutic LACTIN-V (Lactobacillus crispatus CTV-05) on vaginal microbiota and genital tract inflammation among women at high risk of HIV acquisition in South Africa: a phase 2, randomised, placebo-controlled trial

https://www.thelancet.com/journals/lanmic/issue/vol6no6/PIIS2666-5247(25)X0006-9 Effect of the vaginal live biotherapeutic LACTIN-V (Lactobacillus crispatus CTV-05) on vaginal microbiota and genital tract inflammation among women at high risk of HIV acquisition in South Africa: a phase 2, randomised, placebo-controlled trial https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(24)00305-7/fulltext?dgcid=hubspot_update_feature_updatealerts_lanmic&utm_campaign=update-lanmic&utm_medium=email&_hsenc=p2ANqtz--yYlfoMRp1L-syNGH4NK5XRPACjobgovDpHtvdziXnwi0gJj66NSNCREMLP9W_eQJbbY32yp_Ts9_hkIFLcl3e3PiYsw&_hsmi=367196265&utm_content=366877333&utm_source=hs_email

A mother’s journey to change the medical landscape for son’s rare disease

https://rarerevolutionmagazine.com/a-mothers-journey-to-change-the-medical-landscape-for-sons-rare-disease/ 7q11.23: The deletion that changed the lives of a family and ignited a journey for change. How a Brooklyn, NY family—shattered by their son’s diagnosis—uses their pain for good to change the future for Williams syndrome. The mystery that is Williams syndrome It was a chilly night in October 2011 when the Filippazzo family excitedly rushed to the hospital to welcome their new addition. What was supposed to be one of the happiest moments of their lives went dramatically awry. Within minutes of their son Anthony’s birth, a team of doctors were bedside identifying various medical abnormalities but not knowing their etiology. Hypoglycemia, jaundice, need for a blood diffusion and bilateral hearing impairment, to name a few. By eight weeks old Anthony had pneumonia and respiratory synthetic virus. He had severe colic, had extreme difficulty eating and sleeping and exhibited signs of failure to thrive. By 12 weeks old they discovered abnormalities in his heart and deficits in his gross motor skills. By one, he was entirely non-verbal and not meeting milestones. Despite presenting with a myriad of health and developmental problems, it was two years before his parents discovered a geneticist who suspected the cause of his medical problems. With confirmation from microarray genetic testing, the Filippazzo family learned the news. Their son has Williams syndrome.

We empower, partner, and advocate for people living with a rare disease in Europe

https://www.eurordis.org/

L’innovation génomique au service du dépistage néonatal des maladies rares en France

https://www.chu-dijon.fr/le-projet-perigenomed-0 Shaping the Future of Genomic Newborn Screening PERIGENOMED, coordinated by CHU Dijon, is leading a series of research projects on the use of new genomic technologies in newborn screening. As part of this work, they are inviting patient and civil society representatives to share their perspectives. Following a successful in-person event in June 2024, a second edition will take place online on Tuesday 24 June 2025, from 9:15 to 12:30, with interactive breakout sessions from 13:30 to 15:00. This is a unique opportunity to help shape the future of preventive medicine in rare diseases. Register now and make your voice count! https://framaforms.org/inscription-2eme-journee-collaborative-autour-de-lextension-du-depistage-neonatal-mardi-24-juin-2025 Inscription 2ème journée collaborative autour de l'extension du dépistage néonatal - Mardi 24 juin 2025, en ligne https://www.chu-dijon.fr/

Research notebooks Genetic diagnostic techniques

https://www.enfermedades-raras.org/sites/default/files/documentos/21.04.25_gene-diag-tech_uv.pdf FEDER's English Research Notebook FEDER and its Foundation are expanding access to their “CuadERnos de Investigación” (Research Notebooks) with a new international initiative. These themed publications simplify key bioclinical and scientific concepts for the rare disease community. The first English edition focused on “Diagnostic Genetic Techniques” is now available! With 80% of rare diseases having a genetic origin, understanding these techniques is essential for improving diagnosis. Each notebook is created in collaboration with expert contributors to ensure accuracy and relevance. Explore the series and help us expand access to knowledge across borders! https://www.enfermedades-raras.org/que-hacemos/por-la-investigacion/fundacion-feder/conoce-mas-sobre-fundacion-feder/cuadernos-investigacion https://www.enfermedades-raras.org/

Project improves access to medicines for children

https://www.healthawareness.co.uk/childrens-health/project-improves-access-to-medicines-for-children/ In Health Awareness, Maria Cavaller, our Patient Engagement and Therapeutic Development Director, highlights how the Conect4children (c4c) project has been transforming paediatric research in Europe. By embedding young patients and families in trial design and building lasting research infrastructure, c4c lays the groundwork for faster, fairer access to medicines for children with rare diseases. https://conect4children.org/