Aporte a la rutina de la trinchera asistencial donde los conocimientos se funden con las demandas de los pacientes, sus necesidades y las esperanzas de permanecer en la gracia de la SALUD.
domingo, 5 de enero de 2025
sábado, 4 de enero de 2025
Tumor-intrinsic kinome landscape of pancreatic cancer reveals new therapeutic approaches. +++++++++
https://read.qxmd.com/read/39632628/tumor-intrinsic-kinome-landscape-of-pancreatic-cancer-reveals-new-therapeutic-approaches?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Tumor-intrinsic kinome landscape of pancreatic cancer reveals new therapeutic approaches.
Effective therapies for pancreatic ductal adenocarcinoma (PDAC) have been largely elusive. Here, we perform Multiplexed kinase Inhibitor Bead Mass Spectrometry ..
Dec 5, 2024: Cancer Discovery
Head-to-head comparison of palbociclib and ribociclib in first-line treatment of HR-positive/HER2-negative metastatic breast cancer with real-world data from the OPAL registry.
Marc Thill, Mark-Oliver Zahn, Anja Welt, Arnd Nusch, Matthias Zaiss, Kathrin Engelken, Gabriele Kaltenecker, Kai Ringwald, Katja Gratzke, Stephanie Dille, Lisa Kruggel, Martina Jänicke, Holger Schulz, Volker Hagen, Roland Fricker, Elmar Stickeler, Nadia Harbeck, Achim Wöckel, Thomas Decker
International Journal of Cancer. Journal International du Cancer 2024 December 20
https://read.qxmd.com/read/39707595/head-to-head-comparison-of-palbociclib-and-ribociclib-in-first-line-treatment-of-hr-positive-her2-negative-metastatic-breast-cancer-with-real-world-data-from-the-opal-registry?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Breaking the mold: Unconventional T cells in cancer therapy.
Yan-Ruide Li, Kuangyi Zhou, Yichen Zhu, Tyler Halladay, Lili Yang
Cancer Cell 2024 December 6
https://read.qxmd.com/read/39672171/breaking-the-mold-unconventional-t-cells-in-cancer-therapy?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Angioedema.
Gina Lacuesta, Stephen D Betschel, Ellie Tsai, Harold Kim
Allergy, Asthma, and Clinical Immunology 2024 December 9
https://read.qxmd.com/read/39654054/angioedema?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
The effects of low-dose morphine on sleep and breathlessness in COPD: A randomized trial.
Thomas James Altree, Alison Pinczel, Barbara Toson, Kelly Loffler, Anna Hudson, Jim Zeng, Simon Proctor, Ganesh Naik, Sutapa Mukherjee, Peter Catcheside, Andrew Somogyi, David Currow, Danny Eckert
Chest 2024 December 13
https://read.qxmd.com/read/39675518/the-effects-of-low-dose-morphine-on-sleep-and-breathlessness-in-copd-a-randomized-trial?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Potential of Sodium-Glucose Cotransporter-2 Inhibitors in the Management of Heart Failure With Preserved Ejection Fraction: A Narrative Review.
Abdulaziz F Alsuwayh, Mohammed Altawili, Marwan Fahad Alhazmi, Dhuha Faisal M Alotaibi, Alghamdi Omar Rashed, Alharbi Hussam Obaid Abdullah, Ahad Ahmad N Alkenani, Rudayna Adel S Almohammdi, Hamad Fahad M Alotaibi, Fatima Essamaldin Altahir Mohamed Alsharif
Curēus 2024 November
https://read.qxmd.com/read/39697908/potential-of-sodium-glucose-cotransporter-2-inhibitors-in-the-management-of-heart-failure-with-preserved-ejection-fraction-a-narrative-review?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
CAR T-cells in autoimmunity: game changer or stepping stone?
Dimitrios Mougiakakos, Everett Meyer, Georg Schett
Blood 2024 December 19
https://read.qxmd.com/read/39700499/car-t-cells-in-autoimmunity-game-changer-or-stepping-stone?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Antibiotic Treatment of Infections Caused by AmpC-Producing Enterobacterales.
Gianpiero Tebano, Irene Zaghi, Monica Cricca, Francesco Cristini
Pharmacy (Basel, Switzerland) 2024 September 21
https://read.qxmd.com/read/39311133/antibiotic-treatment-of-infections-caused-by-ampc-producing-enterobacterales?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Exploiting bacteria for cancer immunotherapy.
Seong-Young Kwon, Hien Thi-Thu Ngo, Jinbae Son, Yeongjin Hong, Jung-Joon Min
Nature Reviews. Clinical Oncology 2024 August
https://read.qxmd.com/read/38840029/exploiting-bacteria-for-cancer-immunotherapy?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Acute myeloid leukemia management and research in 2025. Hagop M Kantarjian, Courtney D DiNardo, Tapan M Kadia, Naval G Daver, Jessica K Altman, Eytan M Stein, Elias Jabbour, Charles A Schiffer, Amy Lang, Farhad Ravandi CA: a Cancer Journal for Clinicians 2024
Acute myeloid leukemia management and research in 2025.
Hagop M Kantarjian, Courtney D DiNardo, Tapan M Kadia, Naval G Daver, Jessica K Altman, Eytan M Stein, Elias Jabbour, Charles A Schiffer, Amy Lang, Farhad Ravandi
CA: a Cancer Journal for Clinicians 2024
https://read.qxmd.com/read/39656142/acute-myeloid-leukemia-management-and-research-in-2025?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
No, Diet and Exercise Are Not Better Than Drugs for Obesity Yoni Freedhoff, MD ++++++
No, Diet & Exercise Are Not Better Than Obesity Drugs
No, Diet and Exercise Are Not Better Than Drugs for Obesity
Yoni Freedhoff, MD
https://www.medscape.com/viewarticle/no-diet-and-exercise-are-not-better-than-drugs-obesity-2024a1000mgl?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
Injectable Weight Loss Drugs & Environmental Issues
Injectable Weight Loss Drugs: Lifestyle Change for the Environment?
Arthur L. Caplan, PhD
https://www.medscape.com/viewarticle/injectable-weight-loss-drugs-lifestyle-change-environment-2024a1000msg?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
The Easiest Diet Ever
The Easiest Diet Ever
Tamaan K. Osbourne-Roberts, MD, MBA
https://www.medscape.com/viewarticle/easiest-diet-ever-2024a1000lau?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
Focus on Nutrient Density, Not Limiting Foods
Focus on Nutrient Density Instead of Limiting Certain Foods
Brandy Winfree Root, RDN
https://www.medscape.com/viewarticle/focus-nutrient-density-instead-limiting-certain-foods-2024a1000lob?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
Secret to Maintaining Weight Loss With GLP-1s
Maintaining Weight Loss With GLP-1s Needs Lifestyle Changes
Anne L. Peters, MD
https://www.medscape.com/viewarticle/maintaining-weight-loss-glp-1s-needs-lifestyle-changes-2024a1000ld0?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
Time-Restricted Eating May Improve Metabolic Syndrome
Time-Restricted Eating May Help Adults With Metabolic Syndrome Improve Several Health Markers
Lisa M. Basile
https://www.medscape.com/viewarticle/time-restricted-eating-may-help-adults-metabolic-syndrome-2024a1000hy7?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
viernes, 3 de enero de 2025
flok, pioneering patient-led research for inherited metabolic disorders (IMD)
https://rarerevolutionmagazine.com/flok-pioneering-patient-led-research-for-inherited-metabolic-disorders-imd/
To bring about a dramatic and wide reaching change in conditions and attitudes for the rare disease community.
https://rarerevolutionmagazine.com/
RARE REV-inar episode 015: Complexities of genetic diagnosis of mitochondrial diseases 16 ene 2025 12:00 p. m.
https://us02web.zoom.us/webinar/register/WN_X5Dwp1NYR6idBch3K5yLtw#/registration
What role have international organizations played in advancing mitochondrial disease advocacy? How has the collaboration between patient advocacy groups and researchers impacted the field? Join our next RARE Rev-inar on January 26th 2025
Six suicide prevention resources all Veterans need to know Programs and initiatives for all Veterans, no matter when or how you served
Six suicide prevention resources all Veterans need to know
Programs and initiatives for all Veterans, no matter when or how you served
https://news.va.gov/137046/six-suicide-prevention-resources-veterans-know/
Tale of Two Tongues: Oral HPV Soars in Young Adults Liz Scherer +++
Tale of Two Tongues: Oral HPV Soars in Young Adults
Liz Scherer
https://www.medscape.com/s/viewarticle/tale-two-tongues-oral-hpv-soars-young-adults-2024a1000ax7?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
Many Young Adults Who Vaped As Teens Can't Shake the Habit
John Daley
https://www.medscape.com/s/viewarticle/many-young-adults-who-vaped-teens-cant-shake-habit-2024a1000b1l?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
Does Marijuana Harm Your Lungs? The Unclear Truth
Aaron B. Holley, MD
https://www.medscape.com/viewarticle/does-marijuana-harm-your-lungs-unclear-truth-2024a1000mou?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
How Many Young Breast Cancer Survivors Struggle Financially? Edited by Gargi Mukherjee ++++
PATIENT OUTCOMES
Preventive Surgeries Help Young BRCA Patients: New Data
Do Risk-Reducing Surgeries Benefit BRCA Carriers With Early-Onset Breast Cancer History?
Megan Brooks
https://www.medscape.com/viewarticle/do-risk-reducing-surgeries-benefit-brca-carriers-early-onset-2024a1000myt?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
Unique Challenges, Top Concerns of Young Patients With CRC Identified
What Matters Most for Young Patients With CRC: Survey Highlights Top Concerns
Megan Brooks
https://www.medscape.com/viewarticle/what-matters-most-young-patients-crc-survey-highlights-top-2024a1000ki2?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
CAR T for B-ALL: Game Changer for Young Patients?
CAR T for B-ALL: Game Changer for Young Patients?
Randy Dotinga
https://www.medscape.com/s/viewarticle/car-t-b-all-game-changer-young-patients-2024a1000aq2?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
Financial Struggles of Young Breast Cancer Survivors
How Many Young Breast Cancer Survivors Struggle Financially?
Edited by Gargi Mukherjee
https://www.medscape.com/viewarticle/how-many-young-breast-cancer-survivors-struggle-financially-2024a1000mg4?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
jueves, 2 de enero de 2025
Bird flu uptick in US has CDC on alert for pandemic 'red flags': report CDC tracking bird flu cases closely, watching for signs of a pandemic Pilar Arias By Pilar Arias Fox News Published December 31, 2024 8:24am EST
Bird flu uptick in US has CDC on alert for pandemic 'red flags': report
CDC tracking bird flu cases closely, watching for signs of a pandemic
Pilar Arias By Pilar Arias Fox News
Published December 31, 2024 8:24am EST
https://www.foxnews.com/health/bird-flu-uptick-us-has-cdc-alert-pandemic-red-flags-report
Babies born in 2025 will begin Gen Beta, a brand-new generation Gen Beta, born between 2025 and 2039, will be 'shaped by an entirely different world,' experts predict Angelica Stabile By Angelica Stabile Fox News Published January 1, 2025 10:00am EST
Babies born in 2025 will begin Gen Beta, a brand-new generation
Gen Beta, born between 2025 and 2039, will be 'shaped by an entirely different world,' experts predict
Angelica Stabile By Angelica Stabile Fox News
Published January 1, 2025 10:00am EST
https://www.foxnews.com/health/babies-born-2025-begin-gen-beta-brand-new-generation
Warding off dementia means more reading, praying and listening to music: study Downtime decisions may have profound health impacts, say researchers By Maureen Mackey Fox News Published January 1, 2025 2:22pm EST
Warding off dementia means more reading, praying and listening to music: study
Downtime decisions may have profound health impacts, say researchers
By Maureen Mackey Fox News
Published January 1, 2025 2:22pm EST
https://www.foxnews.com/health/warding-off-dementia-reading-praying-listening-music-study
19 drug approvals in 2024 that had 'big clinical impact,' according to GoodRx The FDA approved these 'influential' medications and vaccines this year Angelica Stabile By Angelica Stabile Fox News Published January 1, 2025 4:30am EST
19 drug approvals in 2024 that had 'big clinical impact,' according to GoodRx
The FDA approved these 'influential' medications and vaccines this year
Angelica Stabile By Angelica Stabile Fox News
Published January 1, 2025 4:30am EST
https://www.foxnews.com/health/drug-approvals-2024-big-clinical-impact-according-goodrx
22 health care predictions for 2025 from medical researchers Expectations for cancer, neurology, cardiology, more from experts at Mass General Brigham Melissa Rudy By Melissa Rudy Fox News Published December 31, 2024 4:30am EST
22 health care predictions for 2025 from medical researchers
Expectations for cancer, neurology, cardiology, more from experts at Mass General Brigham
Melissa Rudy By Melissa Rudy Fox News
Published December 31, 2024 4:30am EST
https://www.foxnews.com/health/22-health-care-predictions-2025-medical-researchers
'I'm a psychologist — here's how to finally break your bad habits’ Simply deciding to stop a behavior isn’t enough, the expert says Melissa Rudy By Melissa Rudy Fox News Published January 2, 2025 4:30am EST
'I'm a psychologist — here's how to finally break your bad habits’
Simply deciding to stop a behavior isn’t enough, the expert says
Melissa Rudy By Melissa Rudy Fox News
Published January 2, 2025 4:30am EST
https://www.foxnews.com/health/psychologist-heres-how-finally-break-bad-habits
miércoles, 1 de enero de 2025
Psychosocial Support for Patients With Lipodystrophy By: Madaline Spencer| ++
Psychosocial Support for Patients With Lipodystrophy
By: Madaline Spencer|
https://checkrare.com/psychosocial-support-for-patients-with-lipodystrophy/
Patient Perspective: Challenges of Lipodystrophy
By: Madaline Spencer|
https://checkrare.com/patient-perspective-challenges-of-lipodystrophy/
Stress
https://www.nccih.nih.gov/health/stress?nav=govd
Stress is a physical and emotional reaction that people experience as they encounter challenges in life. When you’re under stress, your body reacts by releasing hormones that produce the “fight-or-flight” response. Your heart rate, breathing rate, and blood pressure go up, your muscles tense, and you sweat more. Occasional stress is a normal coping mechanism. However, long-term stress (also called chronic stress) may contribute to or worsen a range of health problems including digestive disorders, headaches, sleep disorders, and other symptoms. Stress may worsen asthma and has been linked to depression, anxiety, and other mental illnesses.
https://files.nccih.nih.gov/press-reset-on-stress-flyer.pdf
NIH officials assess threat of H5N1 Balancing enhanced vigilance and “business as usual.”
NIH officials assess threat of H5N1
Balancing enhanced vigilance and “business as usual.”
https://www.nih.gov/news-events/news-releases/nih-officials-assess-threat-h5n1
Too Much Coffee Linked to Accelerated Cognitive Decline Pauline Anderson
Too Much Coffee Linked to Accelerated Cognitive Decline
Pauline Anderson
https://www.medscape.com/viewarticle/too-much-coffee-linked-accelerated-cognitive-decline-2024a1000e6q?ecd=mkm_ret_250101_mscpmrk-OUS_BO_etid7103153&uac=148436CN&impID=7103153