sábado, 30 de noviembre de 2024

WEIGHT LOSS AND WELLNESS TRENDS: HYPE OR DOPE?

Weight Loss and Wellness Trends: Hype or Dope? By Ivanhoe Broadcast News on December 8, 2024 https://www.ivanhoe.com/?p=34652&preview=1&_ppp=d5fbeadb5f

SALVAGE HIFU: SAVING THE PROSTATE AFTER RECURRENCE

Salvage HIFU: Saving the Prostate After Recurrence By Ivanhoe Broadcast News on December 7, 2024 https://www.ivanhoe.com/?p=34646&preview=1&_ppp=faaaf042bd

VISION ISSUES AND DEMENTIA: A STRONG CONNECTION

Vision Issues and Dementia: A Strong Connection By Ivanhoe Broadcast News on December 3, 2024 https://www.ivanhoe.com/?p=34633&preview=1&_ppp=2962a368dc

DANGEROUS FOOD ALLERGY REACTIONS: A DRUG-FREE LIFE?

Dangerous Food Allergy Reactions: A Drug-Free Life? By Ivanhoe Broadcast News on December 2, 2024 https://www.ivanhoe.com/?p=34629&preview=1&_ppp=34ffcdcc2f

Modeling Health and Economic Outcomes of Eliminating Sex Disparities in Youth Physical Activity

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2827024?resultClick=3&utm_campaign=hdpulse&utm_medium=email&utm_source=govdelivery An NIMHD-led study published in JAMA Network Open examined the effects of sex disparities in physical activity and sports participation among U.S. youth. The study found that reducing these disparities could prevent 30,000 cases of obesity and other health conditions, saving up to $780 million in lifetime health care costs. This research highlights actionable strategies to support equity in physical activity, such as: Hiring more female coaches. Showcasing women athletes as role models. Implementing mentoring programs. Investing in under-resourced schools and communities to create safe and supportive environments for girls to stay active. The study was led by Dr. Kosuke Tamura, NIH’s Stadtman Investigator and NIH Distinguished Scholar, who directs the Socio-Spatial Determinants of Health Laboratory in NIMHD’s Division of Intramural Research.

Sleep regularity and major adverse cardiovascular events: a device-based prospective study in 72 269 UK adults

https://jech.bmj.com/content/early/2024/10/30/jech-2024-222795?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8p7ASuvTO2uIksORF5DzMiJctKO_Ol8tFHYmWde2YymUrhdkcCkO_411oyEzavw6NBWega57fd5pryR8mEjZVfUk_woA&_hsmi=335871632&utm_content=335871632&utm_source=hs_email Study says: Irregular sleep linked to risk of heart failure, stroke Irregular sleep patterns are linked with a significantly higher risk of major cardiovascular health events like heart failure, stroke, and myocardial infarction, according to a study published yesterday in the Journal of Epidemiology and Community Health. People with moderately irregular sleep schedules can see their risk offset if they still meet the recommended number of hours for sleep for their age group, the study found. But that wasn’t true for the most irregular sleepers. Researchers analyzed eight years of data from more than 72,000 people ages 40 to 79 who, as part of the UK Biobank project, wore tracking devices on their wrist for one week. None of the participants had a history of severe heart problems. Regular vs. irregular patterns were assessed using something called the Sleep Regularity Index — a calculation of the probability that someone is awake or asleep at any two times 24 hours apart. Another study from January also found that sleep regularity was a stronger prediction of mortality risk than sleep duration. Authors of both studies argue that sleep regularity might be even more important to one’s health than sleep duration. Validation of the Sleep Regularity Index in Older Adults and Associations with Cardiometabolic Risk https://www.nature.com/articles/s41598-018-32402-5?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--Qb-FzbrHEkD7UHTwNXcsfGyILTV-XQ9U3fpH-F3Jc0xXQ-ZtTClbpKGR6SrcDHnrCxzjhVPQ4CwJiXh82MAe-wvu1_w&_hsmi=335871632&utm_content=335871632&utm_source=hs_email Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study https://academic.oup.com/sleep/article/47/1/zsad253/7280269?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-99X2KkyM9iPyGu7LcSOVA3LAt6rfc5StWU7uYPOtp3-Ef9iOBSVQdqoa4-tQLeLzZTZ4J3kOJyz2JD3bC8thKVMe4r0A&_hsmi=335871632&utm_content=335871632&utm_source=hs_email

Navigating Diagnosis and Treatment for Primary Biliary Cholangitis: The Integral Role of the Patient Voice // Thyroid Eye Disease: Overview, Diagnosis, and Current and Emerging Treatment Options

Navigating Diagnosis and Treatment for Primary Biliary Cholangitis: The Integral Role of the Patient Voice https://checkrare.com/navigating-diagnosis-and-treatment-for-primary-biliary-cholangitis/ Navigating Diagnosis and Treatment for Primary Biliary Cholangitis: The Integral Role of the Patient Voice Dr. Sonal Kumar, an Assistant Professor of Medicine, and Director of Clinical Hepatology at Weill Cornell Medical College in New York, NY discusses the integral role of the patient voice in navigating treatment decisions and determining an individualized care plan for people living with primary biliary cholangitis (PBC) that reflects their needs and goals. Thyroid Eye Disease: Overview, Diagnosis, and Current and Emerging Treatment Options Thyroid Eye Disease: Overview, Diagnosis, and Current and Emerging Treatment Options Raymond Douglas, MD, PhD, a world-leading clinician and thought leader in thyroid eye disease (TED) who has been integral to developing therapeutics for the disease, provides an overview of TED, including diagnosis challenges and current and emerging treatments for this rare disease. https://checkrare.com/thyroid-eye-disease-overview-and-diagnosis/

Oral Drug Effective for Rare WHIM Syndrome, Approved by FDA

https://ashpublications.org/ashclinicalnews/news/7930/oral-drug-effective-for-rare-whim-syndrome Oral Drug Effective for Rare WHIM Syndrome, Approved by FDA Treatment with mavorixafor reduced infection frequency, severity and duration of infections, and antibiotic use among individuals with warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome in a phase III ­placebo-controlled clinical trial.

Primary Care Providers Can Prescribe with Confidence (Videos)

https://www.fda.gov/drugs/prescribe-confidence/primary-care-providers-can-prescribe-confidence?utm_medium=email&utm_source=govdelivery#words In their own words: Internal medicine doctor Mina Tanaka, M.D. Dr. Tanaka says that many people believe prescribing medications for OUD require more know-how than other medications, but she hasn’t found that to be true. As a physician at Northern Navajo Medical Center in Shiprock, New Mexico, she has found that being a part of someone’s journey to stability is one of the most rewarding things she’s done as a physician. Hear more of her real-life experience prescribing medications for OUD (MOUD) in primary care and learn more about people whose lives have been changed through access to these medications. Watch Dr. Tanaka’s videos, see our previous testimonial videos, and share them with others on social media!

'I'm a pharmacist, and I wouldn't take these 3 vitamin supplements' Some supplements are 'over-consumed' and 'don't have enough nutrients,' expert warns Angelica Stabile By Angelica Stabile Fox News Published November 21, 2024 10:00am EST

'I'm a pharmacist, and I wouldn't take these 3 vitamin supplements' Some supplements are 'over-consumed' and 'don't have enough nutrients,' expert warns Angelica Stabile By Angelica Stabile Fox News Published November 21, 2024 10:00am EST https://www.foxnews.com/health/pharmacist-wouldnt-take-vitamin-supplements

Martha Stewart, 83, stays fit and flexible with this routine Celebrity trainer suggests exercises for older adults to stay 'strong and stable' Angelica Stabile By Angelica Stabile Fox News Published November 25, 2024 2:14pm EST

Martha Stewart, 83, stays fit and flexible with this routine Celebrity trainer suggests exercises for older adults to stay 'strong and stable' Angelica Stabile By Angelica Stabile Fox News Published November 25, 2024 2:14pm EST https://www.foxnews.com/health/martha-stewart-83-stays-fit-flexible-routine

Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition

https://www.nature.com/articles/s42255-024-01166-w New insight into how cancer can beat chemo It’s known that chemotherapy doesn’t always work long-term for cancer patients, as tumor cells can expertly adapt to drugs. But less is known about how that happens. To find out, researchers scanned 3,000 cancer gene cells that are known to be involved with cell metabolism. They were particularly interested in how the level of nutrients in tumors can limit the effect of treatment. The study, published this morning in Nature, sheds light on how cells in glucose-limited tumors are already resistant to some drugs that aim to disrupt cancer metabolism. Some drugs work by preventing cancer cells from making molecules that are an essential part of RNA and DNA. Those molecules (called pyrimidines) are needed to make more food for the cell and to reproduce. Without them, cancer cells can quickly starve and die. But it turns out that in a low-glucose environment, a cancer cell will stretch out its food supplies, consuming what it already has on hand at a slower rate, leading to a slower death. In other experiments, researchers observed two proteins (BAX and BAK) that sit on the surface of the cancer cell mitochondria. When activated, those proteins disintegrate the powerhouse of the cell, leading to cell death. But low-glucose tumor microenvironments weren’t able to activate the proteins. It’s common for solid tumors to have limited glucose because the cells are eating it faster than they can import it, as STAT’s Angus Chen explained to me. The researchers hope the results could be used to develop more effective treatments in the future.

KIDS AND CANNABIS: A DEADLY COMBINATION

Kids and Cannabis: A Dangerous Combination By Ivanhoe Broadcast News on November 30, 2024 https://www.ivanhoe.com/?p=34575&preview=1&_ppp=437291b97b

FROM STROKE TO STRENGTH: BUILDING MENTAL RESILIENCE

From Stroke to Strength: Building Mental Resilience By Ivanhoe Broadcast News on November 28, 2024 https://www.ivanhoe.com/?p=34597&preview=1&_ppp=a70475c3de

A GUT FEELING: MICROBIOME IMPACT ON MIND AND BODY

A Gut Feeling: Microbiome Impact on Mind and Body By Ivanhoe Broadcast News on November 27, 2024 https://www.ivanhoe.com/?p=34594&preview=1&_ppp=aa15222edf

RECOVER FROM HIP SURGERY SIX DAYS SOONER

Recover From Hip Replacement Six Days Sooner By Ivanhoe Broadcast News on November 25, 2024 https://www.ivanhoe.com/?p=34587&preview=1&_ppp=0042c35cb3

jueves, 21 de noviembre de 2024

Switching off drug-resistant cancer

Switching off drug-resistant cancer: With their eclectic mix of mutations, tumors often survive drug treatment. In a new study, researchers found a way to use cancer’s evolutionary potential against it, destroying drug-resistant tumors in animals.

Endometriosis and uterine fibroids and risk of premature mortality: prospective cohort study

https://www.bmj.com/content/387/bmj-2023-078797?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-9WYMoedVXvORQTbtJVm8YA31oln_agZxAchhhZErEnwR8klZmysBjFSLmOGjLhCYN7jWQRXjDyn7W-t55Q5uyOh14i7g&_hsmi=334976770&utm_content=334976770&utm_source=hs_email Study shows: Endometriosis tied to earlier deaths A growing body of evidence has shown that endometriosis (where tissue like that from the inside of the uterus grows on its outside) and uterine fibroids are linked to an increased risk of long-term chronic disease. A study published yesterday in The BMJ provides evidence for a more extreme potential link: Among more than 110,000 cisgender women, endometriosis was associated with a 31% higher risk of death before age 70, primarily driven by gynecological cancers. Uterine fibroids were also associated with higher risk of death specifically from gynecological cancers. Researchers analyzed data from nurses who participated in a survey study that ran from 1989- 2019. Participants were between the ages of 25 and 42 at the beginning of the study, and every couple years reported diagnoses of endometriosis or uterine fibroids. The authors noted that most participants were white, but believed that the large population and long-term results were still useful. https://www.statnews.com/2021/07/08/uterine-fibroids-overlooked-far-too-long/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8ribLrPQQFsHe6ayHdGfWto9cRpg7dUk2BQUKh8wVPZH03642l6BbKKR56DUbx6jJ26IyuQIBYWaDWvZEpPatIEZDDMw&_hsmi=334976770&utm_content=334976770&utm_source=hs_email

Webinar: Person-Centered Care Planning for People With Multiple Chronic Conditions

Webinar: Person-Centered Care Planning for People With Multiple Chronic Conditions: WhenDecember 3, 2024 at 1:00 p.m. ET Register for Dec. 3 Webinar on Care Planning for People with Multiple Chronic Conditions A webinar on Dec. 3 from 1 to 2 p.m. ET will feature preliminary findings from an AHRQ-funded project on approaches to providing person-centered care for people with multiple chronic conditions. Presenters from Oregon Health & Science University will identify persistent barriers and promising strategies for high quality care planning. The project was funded by the Patient-Centered Outcomes Research Trust Fund.

National Center on Substance Abuse and Child Welfare (NCSACW): Family Treatment Courts: An Evidence-Based Approach to Family-Centered Care — Webinar Tuesday, December 17, 1–3 p.m. ET

https://cffutures.zoom.us/webinar/register/WN_UZCgHK3pQUeUucdy1Incqw?utm_source=SAMHSA&utm_campaign=b806c9bc4b-EMAIL_CAMPAIGN_2024_11_14_02_47_COPY_01&utm_medium=email&utm_term=0_-b3ac68c241-167840245#/registration Are you curious about how family treatment courts (FTCs) improve outcomes for families involved with child welfare and affected by substance use disorders (SUDs)? Learn more about FTCs and discover how a family-centered approach helps achieve better outcomes. Presenters and panelists explore how FTCs implement a collaborative approach to resolve barriers in service access and engagement. Join this free event to discover the benefits of a family-centered approach and learn how to help families get the services they need. FTCs have compelling outcomes across various domains: Parents start SUD treatment earlier, stay longer, and experience better outcomes, including successful program completion and decreased substance use. Children placed in out-of-home care (OOHC) experience fewer days in care and increased reunification rates. Families gain increased access to comprehensive services and are less likely to experience recurrence of child maltreatment or OOHC reentry. Attendees will gain a greater understanding of: Foundational elements that make FTCs effective and help parents, children, and other family members obtain equal access to services. FTCs as an evidence-based approach to improve outcomes for families. The importance of a collaborative family-centered approach to FTCs’ success. Resources to implement an FTC.

Interim Guidance for Employers to Reduce Exposure to Novel Influenza A (Such as H5N1 Bird Flu) for People Working with or Exposed to Animals

https://www.cdc.gov/bird-flu/prevention/worker-protection-ppe.html?utm_medium=email&utm_source=govdelivery CDC Interim Guidance for Employers to Reduce Exposure to Novel Influenza A (Such as H5N1 Bird Flu) for People Working with or Exposed to Animals November 12, 2024 This updated interim guidance identifies work tasks that may pose an increased risk of worker exposure to novel influenza A viruses associated with disease in humans and provides recommended controls for each level. Specific recommendations for these work tasks may be updated as CDC learns more during this evolving situation. CDC Expands Guidance to Better Protect Farm Workers and Livestock Owners to Lower the Risk of Becoming infected with Bird Flu https://www.cdc.gov/bird-flu/spotlights/protect-farm-workers-bird-flu-11082024.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fbird-flu%2Fspotlights%2Fprotect-farm-workers-bird-flu.html CDC Expands Guidance to Better Protect Farm Workers and Livestock Owners to Lower the Risk of Becoming Infected with Bird Flu November 8, 2024 This report highlights the need to offer testing and treatment to workers with exposure to sick animals, describes the need to improve and clarify guidance to farm workers and their employers about what personal protective equipment (PPE) to use, and how best to use it to protect themselves and prevent the spread of the virus. Investigation of Avian Influenza A (H5N1) Virus in Dairy Cattle https://www.fda.gov/food/alerts-advisories-safety-information/investigation-avian-influenza-h5n1-virus-dairy-cattle?utm_medium=email&utm_source=govdelivery#Status Status of the Milk Supply Last updated November 8, 2024 The process of pasteurization has helped ensure the health of the American public for more than 100 years. Pasteurization kills harmful bacteria and viruses by heating milk to a specific temperature over time. Even if HPAI virus is detected in raw milk, the current pasteurization process (HTST – High temperature, short time) will inactivate HPAI virus.

Bird flu leaves teen in critical condition after country's first reported case The teen had 'no underlying conditions' and deteriorated quickly, according to BC authorities Angelica Stabile By Angelica Stabile , Melissa Rudy Fox News Published November 13, 2024 12:03pm EST

Bird flu leaves teen in critical condition after country's first reported case The teen had 'no underlying conditions' and deteriorated quickly, according to BC authorities Angelica Stabile By Angelica Stabile , Melissa Rudy Fox News Published November 13, 2024 12:03pm EST https://www.foxnews.com/health/bird-flu-leaves-teen-critical-condition-country-first-reported-case

Breast cancer vaccine update from Cleveland Clinic: ‘A new era’ Experimental vaccine was shown to be ‘well-tolerated’ and produced an ‘immune response,’ researchers say Melissa Rudy By Melissa Rudy Fox News Published November 14, 2024 5:14pm EST

Breast cancer vaccine update from Cleveland Clinic: ‘A new era’ Experimental vaccine was shown to be ‘well-tolerated’ and produced an ‘immune response,’ researchers say Melissa Rudy By Melissa Rudy Fox News Published November 14, 2024 5:14pm EST https://www.foxnews.com/health/breast-cancer-vaccine-update-cleveland-clinic-new-era

5 of the top sources of foodborne illness and how to prevent it One in six people experience food poisoning annually in the US, the CDC says Melissa Rudy By Melissa Rudy Fox News Published November 16, 2024 4:30am EST

5 of the top sources of foodborne illness and how to prevent it One in six people experience food poisoning annually in the US, the CDC says Melissa Rudy By Melissa Rudy Fox News Published November 16, 2024 4:30am EST https://www.foxnews.com/health/top-sources-foodborne-illness-how-prevent