CIENCIASMEDICASNEWS: diciembre 2021

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SMA Screen at birth Save Lives

Repurposing of authorised medicines: pilot to support not-for-profit organisations and academia | European Medicines Agency

Attending the #EURORDISBlackPearlAwards on Rare Disease

Fee-waivers - ECRD2022 - EUROPEAN CONFERENCE ON RARE DISEASES & ORPHAN PRODUCTS

Fee-waivers - ECRD2022

Rare Disease Day 2022 – Raising awareness for patients, families and carers around the world that are affected by rare diseases.

Rare Adult Cancers Included in the Final Report of the European Parliament’s Special Committee on Beating Cancer - EURORDIS - The Voice of Rare Disease Patients in Europe

EURORDIS - The Voice of Rare Disease Patients in Europe

UN Resolution on Persons Living with a Rare Disease - Rare Diseases International

EURORDIS - The Voice of Rare Disease Patients in Europe: UN Resolution is adopted: what does it mean for Europe?

EURORDIS - The Voice of Rare Disease Patients in Europe

jueves, 16 de diciembre de 2021

Symptoms after a third mRNA vaccine among patients with inflammatory bowel disease

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

Study suggests convalescent plasma appears safe but does not prevent SARS-CoV-2 infection

Using fungal vaccine to train stem cells and enhance immune response to infections

Which population does extreme heat affect the most?

Epilepsy Patients Much More Likely to Die of COVID

COVID Vax Leads Rheumatology Patients to Modify Drug Regimens

A Pandemic Silver Lining? Dramatic Drop in Teen Drug Use

Newer Migraine Meds 'Here to Stay,' but Are They More Effective?

Fauci: Boosters Work Against Omicron

Microbiome to blame for weight gain after you quit smoking - ISRAEL21c

How Israelis help the world fight mosquito-borne diseases - ISRAEL21c

Pfizer booster cuts Covid deaths 90% in people over 50 - ISRAEL21c

What we know about Omicron and how to avoid getting it - ISRAEL21c

2 Pfizer doses can’t fight Omicron, but booster helps - ISRAEL21c

Experimental mRNA HIV Vaccine Safe, Shows Promise in Animals | HIV.gov

Determining the Minimally Effective Dose of a Clinical Candidate Adeno-Associated Virus Vector in a Mouse Model of Hemophilia A | Human Gene Therapy

Coronavirus (COVID-19) Update: FDA Authorizes New Long-Acting Monoclonal Antibodies for Pre-exposure Prevention of COVID-19 in Certain Individuals | FDA

NIH study suggests women with disabilities have higher risk of birth complications and death | National Institutes of Health (NIH)

New Links on MedlinePlus

FDA Approves First Drug to Prevent Graft Versus Host Disease | FDA

Low-Back Pain and Complementary Health Approaches

FDA approves first drug to decrease urine protein in IgA nephropathy, a rare kidney disease | FDA

Omicron infects 70 times faster but may cause less severe disease: Study | World News,The Indian Express

miércoles, 15 de diciembre de 2021

Orphanet Journal of Rare Diseases | Home page

Fixing the US Maternal Health Problem: Signs of Hope?

Unrestricted Prescribing of Mifepristone Is Safe, Study Shows

Children and COVID: Weekly Cases Resume Their Climb

COVID-19 Asymptomatic Infection Rate Remains High

Advancing blood research to help patients recover from COVID-19 | NHLBI, NIH

Unraveling the Mysteries of COVID-19 | NHLBI, NIH

National Institutes of Health Sleep Research Plan | NHLBI, NIH

2021 Year in Review | NIDDK

Percentage of adolescents reporting drug use decreased significantly in 2021 as the COVID-19 pandemic endured | National Institutes of Health (NIH)

NIH researchers identify potential AMD drugs with stem-cell based research tool | National Institutes of Health (NIH)

School-Based Suicide Prevention Registration, Fri, Jan 14, 2022 at 2:00 PM | Eventbrite

Understanding novel cancer therapies that help improve survival rates

T-cell therapy with nivolumab safe for Hodgkin's lymphoma - Children's National

Study with largest cohort in the Western world sheds light on Epstein-Barr virus - Children's National

Personalized T cell immunotherapy for brain tumors closer to becoming reality - Children's National

New Links on MedlinePlus

Antiviral drug shows promise against COVID-19 and RSV | National Institutes of Health (NIH)

Viagra associated with reduced risk of Alzheimer’s disease | National Institutes of Health (NIH)

Daytime meals may reduce health risks of night shift work | National Institutes of Health (NIH)

Suicidal tendencies linked to specific genes, correlated with other psychiatric risk factors such as smoking and sleep disturbances - Genetic Literacy Project

martes, 14 de diciembre de 2021

BMC Cancer | Home page

Biology of Sex Differences | Home page

Acta Neuropathologica Communications | Home page

NIH-funded study could help improve deep brain stimulation therapy for OCD | National Institutes of Health (NIH)

SARS-CoV-2 patients exhibit high specialized pro-resolving molecule serum levels

New guidelines for heart-healthy eating

What Are the Different Types of Dementia? | National Institute on Aging

Latest on Omicron Variant and COVID-19 Vaccine Protection – NIH Director's Blog

Planning the Transition to End-of-Life Care in Advanced Cancer (PDQ®)–Health Professional Version - National Cancer Institute

Essiac/Flor Essence (PDQ®)–Health Professional Version - National Cancer Institute

Beyond Omicron: what’s next for COVID’s viral evolution

COVID-19 Update: Omicron Variant

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19: A Randomized Clinical Trial | Critical Care Medicine | JAMA | JAMA Network

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19: A Randomized Clinical Trial | Critical Care Medicine | JAMA | JAMA Network

Comirnaty COVID-19 vaccine: EMA recommends approval for children aged 5 to 11 | European Medicines Agency

First, small study suggests Omicron is a larger threat to Covid-19 immunity

Prevention and management of thrombosis in hospitalised patients with COVID-19 pneumonia - The Lancet Respiratory Medicine

Clinically Suspected Myocarditis Temporally Related to COVID-19 Vaccination in Adolescents and Young Adults | Circulation

BNT162b2 Vaccine Booster and Mortality Due to Covid-19 | NEJM

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19: A Randomized Clinical Trial | Critical Care Medicine | JAMA | JAMA Network

Pfizer confirms Covid-19 pill’s results, potency versus omicron | World News,The Indian Express

lunes, 13 de diciembre de 2021

Theta Burst Brain Stimulation To Improve Memory in Older Adults With Mild Cognitive Impairment

New Links on MedlinePlus

The race to make vaccines for a dangerous respiratory virus

Merck’s COVID pill loses its lustre: what that means for the pandemic

The Human Proteoform Project: Defining the human proteome

'Remarkable' Results With CAR T Cells Could Make Chemo Obsolete

Major COVID-19 Case Growth Expected in Coming Weeks

How Does Atopic Dermatitis Present in Skin of Color?

CDC: Boosters Key in Protecting Against Omicron

Stem Cell Transplant to Generate Testosterone for Hypogonadism?

Nothing Will Stop Us

New Links on MedlinePlus

Children's National to study long-term effects of COVID- Children's National

An assessment of orthopedic surgery residency program websites - Children's National

Increasing the patient’s voice in osteogenesis imperfecta research and care - Children's National

COVID-19 Single-Dose Nasal Vaccine Designed for Infants, Children | NIH: National Institute of Allergy and Infectious Diseases

NIH-funded study could help improve deep brain stimulation therapy for OCD | National Institutes of Health (NIH)

The Lancet Child & Adolescent Health

Pembrolizumab to Prevent Early-Stage Melanoma Recurrence - National Cancer Institute

Tumors Shed Protein to Create Barriers Blocking Immune Cells - National Cancer Institute

Researchers develop a universal SARS-CoV-2 neutralizing antibody

COVID-19 in association with pre-existing mental and physical health issues

New research identifies the cause of Alzheimer’s progression

Seasonal coronaviruses may help estimate SARS-CoV-2 reinfection risk

Sarcopenia and COVID-19

Study suggests pre-existing human common cold coronavirus antibodies hinder SARS-CoV-2 immunity

Workshop on Psychedelics as Therapeutics: Gaps, Challenges & Opportunities Tickets, Wed, Jan 12, 2022 at 9:00 AM | Eventbrite

Omicron variant leads to generally mild symptoms in 40+ known US cases - Genetic Literacy Project

If given, Covid-19 booster must be different vaccine: view in top expert body

domingo, 12 de diciembre de 2021

Main|Amyotrophic lateral sclerosis|PHGKB

Main|Search|PHGKB

mRNA vaccines offer hope for HIV L Morris, Nature Medicine, December 9, 2021

Main|Search|PHGKB

A Phenome Wide Association Study of Severe COVID-19 Genetic Risk Variants JA Regan et al, MEDRXIV, December 11, 2021

Main|Search|PHGKB

The power of genetic diversity in genome-wide association studies of lipids SE Graham et al, Nature, December 9, 2021

Main|Search|PHGKB

Main|Liquid biopsy|PHGKB

Main|Search|PHGKB

Main|Alzheimer's disease|PHGKB

Main|Search|PHGKB

CDC-Authored Publications Update|PHGKB

Precision Health Database| Non-Genomics Precision Health Weekly Scan|PHGKB

Advanced Molecular Detection Clips Database|AMD Clips|PHGKB

Precision Health Database| Genomics Precision Health Weekly Scan|PHGKB

CDC-Authored Genomics and Precision Health Publications Database|Home|PHGKB

Main|Cascade screening or cascade testing|PHGKB

Main|Search|PHGKB

The Use of Machine Learning in Health Care: No Shortcuts on the Long Road to Evidence-based Precision Health | Blogs | CDC

COVID-19 GPH|Home|PHGKB

Omicron Variant: What You Need to Know | CDC

sábado, 11 de diciembre de 2021

What is the immunological response to BNT162b2 mRNA vaccine in immunocompromised patients? - EBioMedicine

Narrating the natural history of live infection by SARS CoV-2 VOC in animal models - EBioMedicine

A point-of-care lateral flow assay for neutralising antibodies against SARS-CoV-2 - EBioMedicine

Safety and efficacy of the mRNA BNT162b2 vaccine against SARS-CoV-2 in five groups of immunocompromised patients and healthy controls in a prospective open-label clinical trial - EBioMedicine

Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2 - EBioMedicine

Immunomodulatory and immunosuppressive medication modification among patients with rheumatic diseases at the time of COVID-19 vaccination - The Lancet Rheumatology

Mental health before and during the pandemic in people with systemic sclerosis - The Lancet Rheumatology

Distinct immune response to CoronaVac in SARS-CoV-2 seropositive and seronegative patients with autoimmune rheumatic disease - The Lancet Rheumatology

Immunogenicity and safety of two doses of the CoronaVac SARS-CoV-2 vaccine in SARS-CoV-2 seropositive and seronegative patients with autoimmune rheumatic diseases in Brazil: a subgroup analysis of a phase 4 prospective study - The Lancet Rheumatology

Immunogenicity and safety of two doses of the CoronaVac SARS-CoV-2 vaccine in SARS-CoV-2 seropositive and seronegative patients with autoimmune rheumatic diseases in Brazil: a subgroup analysis of a phase 4 prospective study - The Lancet Rheumatology

Post-mortem lung tissue: the fossil record of the pathophysiology and immunopathology of severe COVID-19 - The Lancet Respiratory Medicine

Combining active ingredients to treat depression in the wake of COVID-19 - The Lancet Psychiatry

Severe breakthrough COVID-19 cases in the SARS-CoV-2 delta (B.1.617.2) variant era - The Lancet Microbe

WHO international standard for SARS-CoV-2 antibodies to determine markers of protection - The Lancet Microbe

Serial antigen rapid testing in staff of a large acute hospital - The Lancet Infectious Diseases

Booster doses for inactivated COVID-19 vaccines: if, when, and for whom - The Lancet Infectious Diseases

Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials - The Lancet Infectious Diseases

Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials - The Lancet Infectious Diseases

COVID-19 antivirals must not affect HIV drug supply - The Lancet HIV

Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial - The Lancet

Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial - The Lancet

Mixing mRNA, adenoviral, and spike-adjuvant vaccines for protection against COVID-19 - The Lancet

Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK (Com-COV2): a single-blind, randomised, phase 2, non-inferiority trial - The Lancet

Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK (Com-COV2): a single-blind, randomised, phase 2, non-inferiority trial - The Lancet

viernes, 10 de diciembre de 2021

CDC, FDA Sign Off on Pfizer Boosters for 16- and 17-Year-Olds

ECDC warns COVID-19 restrictions must be urgently applied

Neurological sequelae after COVID-19 and COVID-19 vaccines

COVID-19 vaccine and autoimmune disease flare

COVID-19 Around the world weekly highlights: Omicron variant, new lockdown, and flight restrictions…

COVID-19: IDSA rapid guidelines highlight "appropriate" PPE for health care personnel

Experimental mRNA HIV vaccine safe, shows promise in animals | National Institutes of Health (NIH)

New Links on MedlinePlus

Drug allergies: MedlinePlus Medical Encyclopedia

Biotin: MedlinePlus Supplements

Headache | MedlinePlus

Things To Know About Dietary Supplements for Children

No animals harmed in new chip drug tests that are faster and cheaper - ISRAEL21c

A smart polymer that would heal wounds without sutures - ISRAEL21c

What we know about Omicron and how to avoid getting it - ISRAEL21c

Coronavirus (COVID-19) Update: FDA Expands Eligibility for Pfizer-BioNTech COVID-19 Booster Dose to 16- and 17-Year-Olds | FDA

NIH MedlinePlus Magazine

Experimental mRNA HIV Vaccine Safe, Shows Promise in Animals | NIH: National Institute of Allergy and Infectious Diseases

Dermal Filler Do's and Don'ts for Wrinkles, Lips and More | FDA

Dietary Supplements | HIV/AIDS Research | COVID-19 Booster | Mental Health Conversations | Healthy Weight

How Consumers Can Report an Adverse Event or Serious Problem to FDA | FDA

Pregnant? Breastfeeding? FDA Aims to Improve Drug Information | FDA

FDA Proposes Changes to Food Safety Modernization Act Rule to Enhance Safety of Agricultural Water Used on Produce | FDA

FDA Pharmacists Help You Use Medicines Safely | FDA

FDA Expands Authorization of Two Monoclonal Antibodies for Treatment and Post-Exposure Prevention of COVID-19 to Younger Pediatric Patients, Including Newborns | FDA

Coronavirus (COVID-19) Update: FDA Authorizes New Long-Acting Monoclonal Antibodies for Pre-exposure Prevention of COVID-19 in Certain Individuals | FDA

jueves, 9 de diciembre de 2021

US Vaccine Numbers May Be Overestimated, New Study Shows

Vaccine Protection Drops Against Omicron, Making Boosters Crucial

NIH announces winners of data challenge to identify risk factors for first-time pregnancies | National Institutes of Health (NIH)