Can exploring 2 different key pathways boost understanding of gastroesophageal adenocarcinoma?

Can exploring 2 different key pathways boost understanding of gastroesophageal adenocarcinoma? Preclinical data suggest a combined effect on the TIGIT and PD-1 pathways may improve T cell proliferation and enhance T cell activity, which could be beneficial in advancing the scientific understanding of gastroesophageal adenocarcinoma. https://www.medscape.com/infosites/437526.3/isarticle-2?src=0_nl_sm_0&uac=148436CN