PLoS Curr. 2011 Jan 11;3:RRN1208.
Genetic risk profiling for prediction of type 2 diabetes.
Mihaescu R, Meigs J, Sijbrands E, Janssens C.
Erasmus University Medical Center Rotterdam; Massachusetts General Hospital and Dept. of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
Abstract
Type 2 diabetes (T2D) is a common disease caused by a complex interplay between many genetic and environmental factors. Candidate gene studies and recent collaborative genome-wide association efforts revealed at least 38 common single nucleotide polymorphisms (SNPs) associated with increased risk of T2D. Genetic testing of multiple SNPs is considered a potentially useful tool for early detection of individuals at high diabetes risk leading to improved targeting of preventive interventions.
PMID: 21278902 [PubMed - in process]PMCID: PMC3024707
Genetic risk profiling for prediction of type 2 di... [PLoS Curr. 2011] - PubMed result
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