Genome Wide Association Studies in Cardiac Electro... [Heart Rhythm. 2010] - PubMed result

Heart Rhythm. 2010 Apr 24. [Epub ahead of print]

Genome Wide Association Studies in Cardiac Electrophysiology: Recent Discoveries and Implications for Clinical Practice.
Milan DJ, Lubitz SA, Kääb S, Ellinor PT.

Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA; Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA.

Abstract
Genome wide association studies have been increasingly used to study the genetics of complex human diseases. Within the field of cardiac electrophysiology, this technique has been applied to traits such as AF, the QT interval, and several electrocardiographic parameters. While these studies have identified multiple genomic regions associated with each trait, questions remain including the best way to explore the pathophysiology of each association and the potential for clinical utility. This review will summarize recent genome wide association study results within cardiac electrophysiology, and discuss their broader implications in basic science and clinical medicine. Copyright © 2010. Published by Elsevier Inc.

PMID: 20423731 [PubMed - as supplied by publisher]

Genome Wide Association Studies in Cardiac Electro... [Heart Rhythm. 2010] - PubMed result