miércoles, 17 de marzo de 2010

Patients with Pandemic (H1N1) 2009 in Intensive Care Units, Israel



DOI: 10.3201/eid1604.091696
Suggested citation for this article: Kopel E, Amitai Z, Grotto I, Kaliner E, Volovik I. Patients with pandemic (H1N1) 2009 in intensive care units, Israel [letter]. Emerg Infect Dis. 2010 Apr; [Epub ahead of print]


Patients with Pandemic (H1N1) 2009 in Intensive Care Units, Israel

To the Editor: We report results of an active surveillance system established by the Tel Aviv District Health Office in Israel. This surveillance system monitors the daily status of patients with laboratory-confirmed pandemic (H1N1) 2009 virus infection in each of the district’s intensive care units (ICUs), including pediatric ICUs.

Follow-up is maintained by daily phone conversations with medical staff until disease outcome is concluded by discharge, transfer to a long-term rehabilitation facility, or death. Medical records, as well as daily laboratory reports, are collected to confirm or to rule out pandemic (H1N1) 2009 infection.

During July 10–October 10, 2009, our prospective cohort included 17 patients with pandemic (H1N1) 2009 laboratory-confirmed infection who were residents of the district; 12 (70.6%) were male patients. The median age was 44 years (interquartile range 13–72 years). By October 10, 2009, six patients had been discharged, 7 had died, 2 had been transferred to long-term rehabilitation facilities, and 2 remained hospitalized.

Twelve (70.6%) patients had an underlying medical condition, mainly chronic lung disease (6 patients) or chronic cardiovascular disease (5 patients). Two patients were morbidly obese (body mass index >35), and 1 patient was pregnant. Additionally, 3 patients (17.6%) were infected while hospitalized.

Thirteen patients (76.5%) had acute respiratory distress syndrome caused by diffuse viral pneumonitis. Other notable manifestations were acute renal failure (6 patients), sepsis/septic shock (5 patients), and neurologic complications such as Guillain-Barré syndrome, encephalitis, and seizures (3 patients).

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http://www.cdc.gov/eid/content/16/4/pdfs/09-1696.pdf

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